Abstract: A syringe assembly may include a plunger having a stopper. A barrel may be configured to receive the plunger at an open first end. A tip cap may be removably attached to the second end and may form a chamber within the barrel between the plunger and tip cap. The chamber may be configured to contain a sterilization sensitive material. The barrel may be formed of a plastic material having a high barrier property configured to create a barrier between the sterilization sensitive material and gases produced for sterilization purposes such that the sterilization sensitive material remains unchanged during a sterilization procedure.

Abstract: A syringe assembly may include a plunger having a stopper. A barrel may be configured to receive the plunger at an open first end. A tip cap may be removably attached to the second end and may form a chamber within the barrel between the plunger and tip cap. The chamber may be configured to contain a sterilization sensitive material. The barrel may be formed of a plastic material having a high barrier property configured to create a barrier between the sterilization sensitive material and gases produced for sterilization purposes such that the sterilization sensitive material remains unchanged during a sterilization procedure.

Abstract: A syringe assembly may include a plunger having a stopper. A barrel may be configured to receive the plunger at an open first end. A tip cap may be removably attached to the second end and may form a chamber within the barrel between the plunger and tip cap. The chamber may be configured to contain a sterilization sensitive material. The barrel may be formed of a plastic material having a high barrier property configured to create a barrier between the sterilization sensitive material and gases produced for sterilization purposes such that the sterilization sensitive material remains unchanged during a sterilization procedure.

Abstract: A speculum includes an upper bill, a lower bill downwardly of the upper bill, a yoke moveably joining the upper bill to the lower bill, and a ratchet to hold the upper bill and lower bill at a position relative to each other, the ratchet including teeth facing upwardly to selectively hold the upper bill and lower bill. When the ratchet is moved downwardly, the upper bill may pivot freely on the yoke. When the ratchet is moved upwardly, the upper bill is fixed against pivoting. In an example, the yoke includes a pivot about which the upper bill pivots when the ratchet allows and holds the upper bill in position against pressure on the upper bill. A latch prevents the yoke from being removed from the lower bill. Guides allow the upper bill move vertically on the lower bill through the yoke.

Abstract: A speculum includes an upper bill, a lower bill downwardly of the upper bill, a yoke moveably joining the upper bill to the lower bill, and a ratchet to hold the upper bill and lower bill at a position relative to each other, the ratchet including teeth facing upwardly to selectively hold the upper bill and lower bill. When the ratchet is moved downwardly, the upper bill may pivot freely on the yoke. When the ratchet is moved upwardly, the upper bill is fixed against pivoting. In an example, the yoke includes a pivot about which the upper bill pivots when the ratchet allows and holds the upper bill in position against pressure on the upper bill. A latch prevents the yoke from being removed from the lower bill. Guides allow the upper bill move vertically on the lower bill through the yoke.

Abstract: A method of sterilizing a prefilled syringe comprises assembling a syringe assembly and performing at least one ethylene oxide (EtO) sterilization procedure cycle. The assembling step includes inserting a tip cap at a first end of a plunger, filling a non-glass barrel with sterilization sensitive material at a second end of the barrel, and inserting the plunger into the barrel at a second end to seal the sterilization sensitive material within the barrel. The EtO sterilization procedure cycle comprises undergoing a preprocessing stage, a wash and conditioning stage, an EtO sterilization stage and a wash and post exposure stage. Upon completing the EtO sterilization procedure cycle, a resultant pH of the sterilization-sensitive material does not exceed an acceptable pH range as defined by the United States Pharmacopeia. The disclosure also discusses inserting an assembled prefilled syringe into a procedure tray prior to performing the EtO sterilization procedure cycle.

Abstract: A syringe assembly may include a plunger having a stopper. A barrel may be configured to receive the plunger at an open first end. A tip cap may be removably attached to the second end and may form a chamber within the barrel between the plunger and tip cap. The chamber may be configured to contain a sterilization sensitive material. The barrel may be formed of a plastic material having a high barrier property configured to create a barrier between the sterilization sensitive material and gases produced for sterilization purposes such that the sterilization sensitive material remains unchanged during a sterilization procedure.