Patents by Inventor Kelli J. Trei

Kelli J. Trei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polynucleotide constructs for increased lysine production
    Patent number: 8685719
    Abstract: The invention relates to production of lysine, and provides several isolated polynucleotide molecules useful for the production of L-lysine. One such polynucleotide encodes an aspartate kinase (ask), an aspartate-semialdehyde dehydrogenase (asd) and a dihydrodipicolinate reductase (dapB). Other polypeptides encode ask, asd, dapB and a diaminopimelate dehydrogenase (ddh); ask, asd, dapB, ddh and an ORF2 poypeptide; and ask, asd dapB, ddh, ORF2 and a diaminopimelate decarboxylase (lysA). The invention further provides methods of making and using the polynucleotides, and methods to increase the production of L-lysine.
    Type: Grant
    Filed: August 25, 2006
    Date of Patent: April 1, 2014
    Assignee: Archer Daniels Midland Company
    Inventors: Lhing-Yew Li, Kelli J. Trei
  • Polynucleotide constructs encoding aspartate kinase, aspartate-semialdehyde dehydrogenase, and dihydrodipicolinate reductase and related constructs, products, and methods
    Patent number: 7368276
    Abstract: The invention relates to production of lysine, and provides several isolated polynucleotide molecules useful for the production of L-lysine. One such polynucleotide encodes an aspartate kinase (ask), an aspartate-semialdehyde dehydrogenase (asd) and a dihydrodipicolinate reductase. Other polypeptides encode ask, asd, dihydrodipicolinate reductase, and a diaminopimelate dehydrogenase (ddh); ask, asd, dihydrodipicolinate reductase, ddh, and an ORF2 polypeptide; and ask, asd, dihydrodipicolinate reductase, ddh, ORF2 and a diaminopimelate decarboxylase. The invention further provides methods of making and using the polynucleotides, and methods to increase the production of L-lysine. The invention further provides use of isolated polynucleotide molecules encoded by genes native to bacteria of the genus Corynebacterium. The invention further provides host cells bearing the isolated polynucleotide molecules of the invention.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: May 6, 2008
    Assignee: Archer-Daniels-Midland Company
    Inventors: Lhing-Yew Li, Kelli J. Trei
  • Polynucleotide constructs for increased lysine production
    Publication number: 20030055232
    Abstract: The invention relates to production of lysine, and provides several isolated polynucleotide molecules useful for the production of L-lysine. One such polynucleotide encodes an aspartate kinase (ask), an aspartate-semialdehyde dehydrogenase (asd) and a dihydrodipicolinate reductase (dapB). Other polypeptides encode ask, asd, dapB and a diaminopimelate dehydrogenase (ddh); ask, asd, dapB, ddh and an ORF2 poypeptide; and ask, asd dapB, ddh, ORF2 and a diaminopimelate decarboxylase (lysA). The invention further provides methods of making and using the polynucleotides, and methods to increase the production of L-lysine.
    Type: Application
    Filed: February 8, 2002
    Publication date: March 20, 2003
    Applicant: Archer-Daniels-Midland Company
    Inventors: Lhing-Yew Li, Kelli J. Trei