Patents by Inventor Kellie Schaefer

Kellie Schaefer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR MEASURING AND INHIBITING CALPAIN-5 ACTIVITY
    Publication number: 20220364142
    Abstract: Compositions, methods, and kits are provided for assaying calpain-5 activity and inhibition. In particular, novel peptide substrates are provided for detecting calpain-5, measuring calpain-5 activity, and screening for inhibitors of calpain-5 to identify potential therapeutic agents for treating retinal diseases and other diseases associated with calpain-5 hyperactivity. Additionally, novel inhibitors of calpain-5 are also provided.
    Type: Application
    Filed: October 9, 2020
    Publication date: November 17, 2022
    Inventors: Vinit Mahajan, Gabriel Velez, Young Joo Sun, Kellie A Schaefer, Alexander G Bassuk
  • METHODS AND COMPOSITIONS FOR TREATING GENETIC EYE DISEASES
    Publication number: 20190284544
    Abstract: The present disclosure provides CAPN5 substrates and CAPN5 inhibitors, nucleic acids encoding CAPN5 substrates or CAPN5 inhibitors, methods to deliver CAPN5 substrate or CAPN5 inhibitor agents to the eye, and methods of identifying inhibitors of CAPN5.
    Type: Application
    Filed: October 2, 2017
    Publication date: September 19, 2019
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Vinit B. Mahajan, Alexander G. Bassuk, Diana F. Colgan, Gabriel Velez, Kellie Schaefer, Marcus Toral, Shu Wu, Lokesh Gakhar