Patents by Inventor Kelly Dare MOYNIHAN

Kelly Dare MOYNIHAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ALBUMIN BINDING PEPTIDE CONJUGATES AND METHODS THEREOF
    Publication number: 20230248840
    Abstract: The present invention provides a conjugate comprising an albumin binding peptide and a cargo, compositions for directing cargos to the lymphatic system, and vaccines. The methods of the invention can be used to increase an immune response, or to treat cancer or an infectious disease.
    Type: Application
    Filed: April 18, 2023
    Publication date: August 10, 2023
    Inventors: Kelly Dare Moynihan, Rebecca Lynn Holden, Darrell J. Irvine, Bradley Lether Pentelute
  • Albumin binding peptide conjugates and methods thereof
    Patent number: 11642416
    Abstract: The present invention provides a conjugate comprising an albumin binding peptide and a cargo, compositions for directing cargos to the lymphatic system, and vaccines. The methods of the invention can be used to increase an immune response, or to treat cancer or an infectious disease.
    Type: Grant
    Filed: July 9, 2021
    Date of Patent: May 9, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Kelly Dare Moynihan, Rebecca Lynn Holden, Darrell J. Irvine, Bradley Lether Pentelute
  • FUSIONS WITH CD8 ANTIGEN BINDING MOLECULES FOR MODULATING IMMUNE CELL FUNCTION
    Publication number: 20220162314
    Abstract: Provided herein are anti-CD8 antigen binding molecules and fusion polypeptides comprising the CD8 antigen binding molecules for selectively modulating the function of CD8+ T cells over other immune cells. In addition, the present disclosure also provides polynucleotides encoding the disclosed antigen binding molecules and fusion polypeptides, and vectors and host cells comprising such polynucleotides. The present disclosure further provides methods for producing the antigen binding molecules and fusion polypeptides, pharmaceutical compositions comprising the same, and uses thereof.
    Type: Application
    Filed: October 22, 2021
    Publication date: May 26, 2022
    Inventors: Yik Andy YEUNG, Ivana DJURETIC, Paul BESSETTE, Wei CHEN, Sherman Michael CHIN, Kelly Dare MOYNIHAN, Henry C. NGUYEN, Irene NI, Danielle C. PAPPAS, Terrence PARK
  • ALBUMIN BINDING PEPTIDE CONJUGATES AND METHODS THEREOF
    Publication number: 20210330800
    Abstract: The present invention provides a conjugate comprising an albumin binding peptide and a cargo, compositions for directing cargos to the lymphatic system, and vaccines. The methods of the invention can be used to increase an immune response, or to treat cancer or an infectious disease.
    Type: Application
    Filed: July 9, 2021
    Publication date: October 28, 2021
    Inventors: Kelly Dare MOYNIHAN, Rebecca Lynn HOLDEN, Darrell J. IRVINE, Bradley Lether PENTELUTE
  • Albumin binding peptide conjugates and methods thereof
    Patent number: 11077199
    Abstract: The present invention provides a conjugate comprising an albumin binding peptide and a cargo, compositions for directing cargos to the lymphatic system, and vaccines. The methods of the invention can be used to increase an immune response, or to treat cancer or an infectious disease.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: August 3, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Kelly Dare Moynihan, Rebecca Lynn Holden, Darrell J. Irvine, Bradley Lether Pentelute
  • Methods of treating cancer cells expressing tumor-associated integrins
    Patent number: 10888603
    Abstract: The present invention provides a method of treating cancer with a combination of IL-2 (e.g., extended-PK IL-2), an integrin-binding-Fc fusion protein, and a cancer vaccine. The methods of the invention can be used to treat a broad range of cancer types.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: January 12, 2021
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Massachusetts Institute of Technology
    Inventors: Karl Dane Wittrup, Darrell J. Irvine, Cary Francis Opel, Kelly Dare Moynihan, Jennifer R. Cochran, Byron Hua Kwan
  • SYNERGISTIC TUMOR TREATMENT WITH IL-2, AN INTEGRIN-BINDING-FC FUSION PROTEIN, AND A CANCER VACCINE
    Publication number: 20190054145
    Abstract: The present invention provides a method of treating cancer with a combination of IL-2 (e.g., extended-PK IL-2), an integrin-binding-Fc fusion protein, and a cancer vaccine. The methods of the invention can be used to treat a broad range of cancer types.
    Type: Application
    Filed: February 10, 2017
    Publication date: February 21, 2019
    Inventors: Karl Dane WITTRUP, Darrell J. IRVINE, Cary Francis OPEL, Kelly Dare MOYNIHAN, Jennifer R. COCHRAN, Byron Hua KWAN
  • ALBUMIN BINDING PEPTIDE CONJUGATES AND METHODS THEREOF
    Publication number: 20190046654
    Abstract: The present invention provides a conjugate comprising an albumin binding peptide and a cargo, compositions for directing cargos to the lymphatic system, and vaccines. The methods of the invention can be used to increase an immune response, or to treat cancer or an infectious disease.
    Type: Application
    Filed: August 9, 2018
    Publication date: February 14, 2019
    Inventors: Kelly Dare MOYNIHAN, Rebecca Lynn HOLDEN, Darrell J. IRVINE, Bradley Lether PENTELUTE
  • SYNERGISTIC TUMOR TREATMENT WITH IL-2, A THERAPEUTIC ANTIBODY, AND A CANCER VACCINE
    Publication number: 20170224777
    Abstract: The present invention provides a method of treating cancer with a combination of IL-2 (e.g., extended-PK IL-2), a therapeutic antibody or fragment thereof, and a cancer vaccine. The methods of the invention can be used to treat a broad range of cancer types.
    Type: Application
    Filed: August 12, 2015
    Publication date: August 10, 2017
    Inventors: Karl Dane WITTRUP, Darrell IRVINE, Cary Francis OPEL, Kelly Dare MOYNIHAN
  • SYNERGISTIC TUMOR TREATMENT WITH IL-2, A THERAPEUTIC ANTIBODY, AND AN IMMUNE CHECKPOINT BLOCKER
    Publication number: 20170216403
    Abstract: The present invention provides a method of treating cancer with a combination of IL-2 (e.g., extended-PK IL-2), a therapeutic antibody or fragment thereof, and an immune checkpoint blocker. The methods of the invention can be used to treat a broad range of cancer types.
    Type: Application
    Filed: August 12, 2015
    Publication date: August 3, 2017
    Inventors: Karl Dane WITTRUP, Darrell IRVINE, Cary Francis OPEL, Kelly Dare MOYNIHAN