Patents by Inventor Kelly R. Stevens

Kelly R. Stevens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IN SITU EXPANSION OF ENGINEERED DEVICES FOR REGENERATION
    Publication number: 20220354994
    Abstract: Engineered human tissue seed constructs are provided that are suitable for implantation in subjects. Methods of making and using the engineered tissue seed constructs are provided.
    Type: Application
    Filed: April 22, 2022
    Publication date: November 10, 2022
    Inventors: Sangeeta N. Bhatia, Kelly R. Stevens, Christopher S. Chen
  • In situ expansion of engineered devices for regeneration
    Patent number: 11338065
    Abstract: Engineered human tissue seed constructs are provided that are suitable for implantation in subjects. Methods of making and using the engineered tissue seed constructs are provided.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: May 24, 2022
    Assignees: Massachusetts Institute of Technology, Trustees of Boston University
    Inventors: Sangeeta N. Bhatia, Kelly R. Stevens, Christopher S. Chen
  • Biomaterials for enhanced implant-host integration
    Patent number: 11324858
    Abstract: The present disclosure provides patterned biomaterials having organized cords and extracellular matrix embedded in a 3D scaffold. According, the present disclosure provides compositions and applications for patterned biomaterials. Pre-patterning of these biomaterials can lead to enhanced integration of these materials into host organisms, providing a strategy for enhancing the viability of engineered tissues by promoting vascularization.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: May 10, 2022
    Assignees: The Trustees of the University of Pennsylvania, Massachusetts Institute of Technology
    Inventors: Christopher S. Chen, Jan D. Baranski, Ritika Chaturvedi, Michael T. Yang, Kelly R. Stevens, Sangeeta N. Bhatia
  • Situ expansion of engineered devices for regeneration
    Patent number: 11266766
    Abstract: Engineered human tissue seed constructs are provided that are suitable for implantation in subjects. Methods of making and using the engineered tissue seed constructs are provided.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: March 8, 2022
    Assignees: Massachusetts Institute of Technology, Trustees of Boston University
    Inventors: Sangeeta N. Bhatia, Kelly R. Stevens, Christopher S. Chen
  • BIOMATERIALS FOR ENHANCED IMPLANT-HOST INTEGRATION
    Publication number: 20210213171
    Abstract: The present disclosure provides patterned biomaterials having organized cords and extracellular matrix embedded in a 3D scaffold. According, the present disclosure provides compositions and applications for patterned biomaterials. Pre-patterning of these biomaterials can lead to enhanced integration of these materials into host organisms, providing a strategy for enhancing the viability of engineered tissues by promoting vascularization.
    Type: Application
    Filed: March 26, 2021
    Publication date: July 15, 2021
    Inventors: Christopher S. CHEN, Jan D. BARANSKI, Ritika CHATURVEDI, Michael T. YANG, Kelly R. STEVENS, Sangeeta N. BHATIA
  • SITU EXPANSION OF ENGINEERED DEVICES FOR REGENERATION
    Publication number: 20210213173
    Abstract: Engineered human tissue seed constructs are provided that are suitable for implantation in subjects. Methods of making and using the engineered tissue seed constructs are provided.
    Type: Application
    Filed: March 26, 2021
    Publication date: July 15, 2021
    Inventors: Sangeeta N. BHATIA, Kelly R. STEVENS, Christopher S. CHEN
  • IN SITU EXPANSION OF ENGINEERED DEVICES FOR REGENERATION
    Publication number: 20190076578
    Abstract: Engineered human tissue seed constructs are provided that are suitable for implantation in subjects. Methods of making and using the engineered tissue seed constructs are provided.
    Type: Application
    Filed: October 7, 2016
    Publication date: March 14, 2019
    Inventors: Sangeeta N. BHATIA, Kelly R. STEVENS, Christopher S. CHEN
  • Inverse patterning process for three-dimensional multi-compartmental micro-organization of multiple cell types
    Patent number: 10072257
    Abstract: The invention features an “inverse patterning” or “Intaglio-Void/Embed-Relief Topographic (In VERT) molding” manufacturing process for generating high-resolution three-dimensional (3D) multi-cellular microstructures in distinct cellular compartments of a single hydrogel. The platform has general utility in the development of engineered tissues for human therapies, drug testing, and disease models. Additionally, the platform can serve as a model system for studying 3D cell-cell interactions in fields as diverse as stem cell biology to the development of cancer therapeutics.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: September 11, 2018
    Assignee: Massachusetts Institute of Technology
    Inventors: Sangeeta N. Bhatia, Kelly R. Stevens
  • INVERSE PATTERNING PROCESS FOR THREE-DIMENSIONAL MULTI-COMPARTMENTAL MICRO-ORGANIZATION OF MULTIPLE CELL TYPES
    Publication number: 20150082468
    Abstract: The invention features an “inverse patterning” or “Intaglio-Void/Embed-Relief Topographic (In VERT) molding” manufacturing process for generating high-resolution three-dimensional (3D) multi-cellular microstructures in distinct cellular compartments of a single hydrogel. The platform has general utility in the development of engineered tissues for human therapies, drug testing, and disease models. Additionally, the platform can serve as a model system for studying 3D cell-cell interactions in fields as diverse as stem cell biology to the development of cancer therapeutics.
    Type: Application
    Filed: February 28, 2013
    Publication date: March 19, 2015
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Sangeeta N. Bhatia, Kelly R. Stevens