Abstract: Provided herein are IL-2 muteins, IL-2 mutein Fc-fusion molecules, anti-IL-2 antibodies, and complexes comprising an anti IL-2 antibody bound to an IL-2 cytokine that preferentially expand and activate T regulatory cells and are amenable to large scale production. Also provided herein are variant human IgG1 Fc molecules lacking or with highly reduced effector function and high stability despite lacking glycosylation at N297. Also provided herein are linker peptides that are glycosylated when expressed in mammalian cells. Also provided herein are methods of making and using the compositions of the present invention.

Abstract: A polymer compound containing groups having the chemical structure: where NH2 is a primary amine, and R is not hydrogen, and a polymer backbone wherein two of the R groups are part of the polymer backbone. A method of synthesizing a polymer includes polymerizing amine-convertible monomers to produce a polymer, causing a deprotection reaction with the polymer to form an isocyanate, decomposing the isocyanate to form a polymer containing primary amines. A method to separate CO2 from other gases comprising using a sorbent containing a polymer compound having the structure: where NH2 is a primary amine, and R is not hydrogen, and a polymer backbone wherein two of the R groups are part of the polymer backbone.

Abstract: A composition of matter has a molecularly imprinted polymer having templated pores, and a reactive material occupying a portion of each pore, the reactive material selected to react when an analyte material for which the cavities are templated enters the cavities. A method of synthesizing a molecularly imprinted polymer includes arranging monomers around a template molecule having a reactive component and an analyte component, polymerizing the monomers, removing the template molecule, and reintroducing the reactive component of the template molecule. A method of detecting an analyte includes exposing a molecularly imprinted polymer to a fluid, the polymer having templated pores containing a detector material that is reactive to an analyte.