Patents by Inventor Kelsey Nicole RETTING

Kelsey Nicole RETTING has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Engineered Three-Dimensional Skin Tissues, Arrays Thereof, and Methods of Making the Same
    Publication number: 20230201420
    Abstract: Disclosed are bioprinted, three-dimensional, biological skin tissues comprising: a dermal layer comprising dermal fibroblasts; and an epidermal layer comprising keratinocytes, the epidermal layer in contact with the dermal layer to form the three-dimensional, engineered, biological skin tissue. Also disclosed are arrays of engineered skin tissues and methods of making engineered skin tissues.
    Type: Application
    Filed: December 19, 2022
    Publication date: June 29, 2023
    Inventors: Kelsey Nicole RETTING, Colin M. O'NEILL, Deborah Lynn Greene NGUYEN, Sharon C. PRESNELL, Jessica LANGER, Guive BALOOCH, Elizabeth WU, Julien DEMAUDE
  • Engineered intestinal tissue and uses thereof
    Patent number: 11655456
    Abstract: Disclosed are methods of assessing the ability of a candidate therapeutic agent to reverse, reduce or prevent intestinal injury by a potential toxic agent using a three-dimensional, engineered, bioprinted, biological intestinal tissue model. Also disclosed are methods of assessing the effect of an agent on intestinal function, the method comprising contacting the agent with a three-dimensional, engineered, bioprinted, biological intestinal tissue model.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: May 23, 2023
    Assignee: Organovo, Inc.
    Inventors: Kelsey Nicole Retting, Deborah Lynn Greene Nguyen, Lauran Madden
  • Engineered three-dimensional skin tissues, arrays thereof, and methods of making the same
    Patent number: 11529436
    Abstract: Disclosed are bioprinted, three-dimensional, biological skin tissues comprising: a dermal layer comprising dermal fibroblasts; and an epidermal layer comprising keratinocytes, the epidermal layer in contact with the dermal layer to form the three-dimensional, engineered, biological skin tissue. Also disclosed are arrays of engineered skin tissues and methods of making engineered skin tissues.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: December 20, 2022
    Assignees: Organovo, Inc., L'Oreal
    Inventors: Kelsey Nicole Retting, Colin M. O'Neill, Deborah Lynn Greene Nguyen, Sharon C. Presnell, Jessica Langer, Guive Balooch, Elizabeth Wu, Julien Demaude
  • Engineered Intestinal Tissue and Uses Thereof
    Publication number: 20220204941
    Abstract: Disclosed are methods of assessing the ability of a candidate therapeutic agent to reverse, reduce or prevent intestinal injury by a potential toxic agent using a three-dimensional, engineered, bioprinted, biological intestinal tissue model. Also disclosed are methods of assessing the effect of an agent on intestinal function, the method comprising contacting the agent with a three-dimensional, engineered, bioprinted, biological intestinal tissue model.
    Type: Application
    Filed: March 15, 2022
    Publication date: June 30, 2022
    Inventors: Kelsey Nicole RETTING, Deborah Lynn Greene NGUYEN, Lauran MADDEN
  • Engineered Intestinal Tissue and Uses Thereof
    Publication number: 20220204942
    Abstract: Disclosed are methods of assessing the ability of a candidate therapeutic agent to reverse, reduce or prevent intestinal injury by a potential toxic agent using a three-dimensional, engineered, bioprinted, biological intestinal tissue model. Also disclosed are methods of assessing the effect of an agent on intestinal function, the method comprising contacting the agent with a three-dimensional, engineered, bioprinted, biological intestinal tissue model.
    Type: Application
    Filed: March 15, 2022
    Publication date: June 30, 2022
    Inventors: Kelsey Nicole RETTING, Deborah Lynn Greene NGUYEN, Lauran MADDEN
  • METHODS FOR TISSUE FABRICATION
    Publication number: 20220195380
    Abstract: Disclosed herein are improved methods for fabricating bioprinted, three-dimensional, biological tissues. The methods relate to exposures to low temperatures, incubations at low temperatures of various durations, and fabrication in environments without structural cross-linking treatments.
    Type: Application
    Filed: October 1, 2021
    Publication date: June 23, 2022
    Inventors: Kelsey Nicole RETTING, Deborah Lynn Greene NGUYEN, Sharon C. PRESNELL, Shelby Marie KING
  • Engineered Intestinal Tissue and Uses Thereof
    Publication number: 20210284967
    Abstract: Disclosed are methods of assessing the ability of a candidate therapeutic agent to reverse, reduce or prevent intestinal injury by a potential toxic agent using a three-dimensional, engineered, bioprinted, biological intestinal tissue model. Also disclosed are methods of assessing the effect of an agent on intestinal function, the method comprising contacting the agent with a three-dimensional, engineered, bioprinted, biological intestinal tissue model.
    Type: Application
    Filed: November 10, 2017
    Publication date: September 16, 2021
    Inventors: Kelsey Nicole RETTING, Deborah Lynn Greene NGUYEN, Lauran MADDEN
  • Engineered Three-Dimensional Skin Tissues, Arrays Thereof, and Methods of Making the Same
    Publication number: 20180272035
    Abstract: Disclosed are bioprinted, three-dimensional, biological skin tissues comprising: a dermal layer comprising dermal fibroblasts; and an epidermal layer comprising keratinocytes, the epidermal layer in contact with the dermal layer to form the three-dimensional, engineered, biological skin tissue. Also disclosed are arrays of engineered skin tissues and methods of making engineered skin tissues.
    Type: Application
    Filed: November 5, 2015
    Publication date: September 27, 2018
    Inventors: Kelsey Nicole Retting, Colin M. O'Neill, Deborah Lynn Greene Nguyen, Sharon C. Presnell, Jessica Langer, Guive Balooch, Elizabeth Wu, Julien Demaude
  • Improved Methods for Tissue Fabrication
    Publication number: 20180265839
    Abstract: Disclosed herein are improved methods for fabricating bioprinted, three-dimensional, biological tissues. The methods relate to exposures to low temperatures, incubations at low temperatures of various durations, and fabrication in environments without structural cross-linking treatments.
    Type: Application
    Filed: November 9, 2016
    Publication date: September 20, 2018
    Inventors: Kelsey Nicole RETTING, Deborah Lynn Greene NGUYEN, Sharon C. PRESNELL, Shelby Marie KING
  • METHODS FOR TISSUE FABRICATION
    Publication number: 20170130192
    Abstract: Disclosed herein are improved methods for fabricating bioprinted, three-dimensional, biological tissues. The methods relate to exposures to low temperatures, incubations at low temperatures of various durations, and fabrication in environments without structural cross-linking treatments.
    Type: Application
    Filed: November 9, 2015
    Publication date: May 11, 2017
    Inventors: Kelsey Nicole RETTING, Deborah Lynn Greene NGUYEN, Sharon C. PRESNELL, Shelby Marie KING
  • ENGINEERED THREE-DIMENSIONAL SKIN TISSUES, ARRAYS THEREOF, AND METHODS OF MAKING THE SAME
    Publication number: 20160122723
    Abstract: Disclosed are bioprinted, three-dimensional, biological skin tissues comprising: a dermal layer comprising dermal fibroblasts; and an epidermal layer comprising keratinocytes, the epidermal layer in contact with the dermal layer to form the three-dimensional, engineered, biological skin tissue. Also disclosed are arrays of engineered skin tissues and methods of making engineered skin tissues.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 5, 2016
    Inventors: Kelsey Nicole RETTING, Colin M. O'Neill, Deborah Lynn Greene NGUYEN, Sharon C. PRESNELL