Patents by Inventor Kelvin Davies

Kelvin Davies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING SMOOTH MUSCLE DYSFUNCTION
    Publication number: 20160184455
    Abstract: The present disclosure provides compositions and methods to improve one or more signs or symptoms of smooth muscle diseases. Compositions of the disclosure may include a plasmid vector containing a variant nucleic that encodes for a variant amino acid sequence of the alpha subunit of the BK potassium channel. Compositions may further include a nanoparticle delivery system. Compositions and methods of use of the disclosure may be used to treat, for example, over active bladder (OAB) syndrome and erectile dysfunction (ED).
    Type: Application
    Filed: August 5, 2014
    Publication date: June 30, 2016
    Inventors: Arnold Melman, Kelvin Davies, David Spray, Yi Wang, Joel Friedman, Mahantash Nadavi
  • GENE TRANSFER FOR REGULATING SMOOTH MUSCLE TONE
    Publication number: 20150366942
    Abstract: The invention provides methods of regulating smooth muscle tone in a subject, comprising the introduction, into smooth muscle cells of the subject, of a DNA sequence encoding a potassium channel protein involved in the regulation of smooth muscle tone, and expression of the DNA sequence in a sufficient number of smooth muscle cells of the subject to regulate smooth muscle tone in the subject. The invention provides methods of gene transfer for treating erectile dysfunction, bladder dysfunction, and other smooth muscle disorders.
    Type: Application
    Filed: September 2, 2015
    Publication date: December 24, 2015
    Applicant: Albert Einstein College of Medicine of Yeshiva University
    Inventors: George J. Christ, Kelvin Davies, Arnold Melman
  • GENE TRANSFER FOR REGULATING SMOOTH MUSCLE TONE
    Publication number: 20140088176
    Abstract: The invention provides methods of regulating smooth muscle tone in a subject, comprising the introduction, into smooth muscle cells of the subject, of a DNA sequence encoding a potassium channel protein involved in the regulation of smooth muscle tone, and expression of the DNA sequence in a sufficient number of smooth muscle cells of the subject to regulate smooth muscle tone in the subject. The invention provides methods of gene transfer for treating erectile dysfunction, bladder dysfunction, and other smooth muscle disorders.
    Type: Application
    Filed: March 18, 2013
    Publication date: March 27, 2014
    Applicant: Albert Einstein College of Medicine of Yeshiva University
    Inventors: George J. Christ, Kelvin Davies, Arnold Melman
  • GENE TRANSFER FOR REGULATING SMOOTH MUSCLE TONE
    Publication number: 20090068152
    Abstract: The invention provides methods of regulating smooth muscle tone in a subject, comprising the introduction, into smooth muscle cells of the subject, of a DNA sequence encoding a potassium channel protein involved in the regulation of smooth muscle tone, and expression of the DNA sequence in a sufficient number of smooth muscle cells of the subject to regulate smooth muscle tone in the subject. The invention provides methods of gene transfer for treating erectile dysfunction, bladder dysfunction, and other smooth muscle disorders.
    Type: Application
    Filed: November 23, 2004
    Publication date: March 12, 2009
    Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY
    Inventors: George J. Christ, Kelvin Davies, Arnold Melman