Abstract: Systems and methods described herein provide for the estimation of the maximum reservoir pressure at which fluid can be injected into a reservoir before causing conductivity increase due to fracture/fault reactivation. An exemplary method includes computing the maximum reservoir pressure for the location of interest prior to fracture/fault reactivation at a given depleted reservoir pressure based on a computed probability of non-exceedance for a field or laboratory estimate of the maximum reservoir pressure prior to fracture/fault reactivation and a computed pressure distribution including a range of potential maximum reservoir pressures for the location of interest prior to fracture/fault reactivation at the given depleted reservoir pressure. The method also includes outputting the computed maximum reservoir pressure as the estimated maximum reservoir pressure for performing a fluid injection operation for the location of interest.