Patents by Inventor Ken Aoshima

Ken Aoshima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260253687
    Abstract: An information processing device inputs information of a patient to a prediction model trained using training data, in which at least four variables that fall under at least any of first information relating to orientation, second information relating to memory, third information relating to memory of a holiday, a family gathering, a reservation, or schedule of taking medication in IADL, or memory of a meal or actual work of travel in IADL, and fourth information relating to positive/negative of a biomarker are associated with presence/absence of advance of a symptom of mild cognitive impairment (MCI) or mild Alzheimer's dementia (mild AD), with the information of the patient corresponding to each of the at least four variables, and predicts a probability of advance of a symptom of mild cognitive impairment (MCI) or mild Alzheimer's dementia (mild AD) in the patient.
    Type: Application
    Filed: March 15, 2024
    Publication date: August 27, 2026
    Inventors: Ken AOSHIMA, Yoshitaka NAKAMURA, Yuji MIURA, Kenichi ANABUKI, Ryo DAIRIKI, Momoka TSUNEYOSHI, Emiko SEGAWA, Kazuya NAGAOKA
  • Patent number: 9581604
    Abstract: Desmosterol alone, the combination of desmosterol and amyloid beta, the combination of desmosterol and gelsolin and the combination of desmosterol, amyloid beta and gelsolin can be used as in-blood biomarkers for Alzheimer's disease or mild cognitive impairment. A method for evaluating the effect of a candidate for a therapeutic agent to treat Alzheimer's disease or mild cognitive impairment, a method for aiding the diagnosis of Alzheimer's disease or mild cognitive impairment, and a method for diagnosing Alzheimer's disease or mild cognitive impairment are provided in which the biomarkers are used.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: February 28, 2017
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Yoshiaki Sato, Ken Aoshima, Francois Bernier
  • Publication number: 20130266589
    Abstract: Desmosterol alone, the combination of desmosterol and amyloid beta, the combination of desmosterol and gelsolin and the combination of desmosterol, amyloid beta and gelsolin can be used as in-blood biomarkers for Alzheimer's disease or mild cognitive impairment. A method for evaluating the effect of a candidate for a therapeutic agent to treat Alzheimer's disease or mild cognitive impairment, a method for aiding the diagnosis of Alzheimer's disease or mild cognitive impairment, and a method for diagnosing Alzheimer's disease or mild cognitive impairment are provided in which the biomarkers are used.
    Type: Application
    Filed: June 23, 2011
    Publication date: October 10, 2013
    Applicant: EISAI R&D MANAGEMENT CO., LTD.
    Inventors: Yoshiaki Sato, Ken Aoshima, Francois Bernier