Patents by Inventor Ken B. Nichols

Ken B. Nichols has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acellular dermal matrix and method of use thereof for grafting
    Patent number: 8067149
    Abstract: A method for processing and preserving an acellular collagen-based tissue matrix for transplantation is disclosed. The method includes the steps of processing biological tissues with a stabilizing solution to reduce procurement damage, treatment with a processing solution to remove cells, treatment with a cryoprotectant solution followed by freezing, drying, storage and rehydration under conditions that preclude functionally significant damage and reconstitution with viable cells.
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: November 29, 2011
    Assignee: LifeCell Corporation
    Inventors: Stephen A. Livesey, Anthony A. del Campo, Abhijit Nag, Ken B. Nichols, Edward S. Griffey, Christopher Coleman
  • Method for processing and preserving collagen-based tissues for transplantation
    Publication number: 20030035843
    Abstract: A method for processing and preserving an acellular collagen-based tissue matrix for transplantation is disclosed. The method includes the steps of processing biological tissues with a stabilizing solution to reduce procurement damage, treatment with a processing solution to remove cells, treatment with a cryoprotectant solution followed by freezing, drying, storage and rehydration under conditions that preclude functionally significant damage and reconstitution with viable cells.
    Type: Application
    Filed: June 7, 2002
    Publication date: February 20, 2003
    Applicant: LifeCell Corporation, a Delaware corporation
    Inventors: Stephen A. Livesey, Anthony A. del Campo, Abhijit Nag, Ken B. Nichols, Edward S. Griffey, Christopher Coleman
  • Cryoprotective solutions comprising DMSO, PG, 2,3-butanediol,raffinose and PVP
    Patent number: 6194136
    Abstract: This invention relates to methods, apparatus and solutions for cryopreserving microscopic biological materials for biologically extended periods of time. The method comprises treating a suspension of biological material, in an appropriate buffer, with a cryoprotectant or combination of cryoprotectants which raises the glass transition temperature range of the sample. One or more dry protectants may be added to the cryosolution. The cryosolution is then nebulized and rapidly cooled with novel apparatus, dried by molecular distillation, stored and then rehydrated in a buffer prior to its use. The solutions comprise novel mixtures of cryoprotectants.
    Type: Grant
    Filed: July 13, 1998
    Date of Patent: February 27, 2001
    Assignee: LifeCell Corporation
    Inventors: Stephen A. Livesey, Anthony A. del Campo, Abhijit Nag, Ken B. Nichols, Carmen Piunno, David P. Ross
  • Apparatus for cryopreparation, dry stabilization and rehydration of biological suspensions
    Patent number: 5780295
    Abstract: This invention relates to methods, apparatus and solutions for cryopreserving microscopic biological materials for biologically extended periods of time. The method comprises treating a suspension of biological material, in an appropriate buffer, with a cryoprotectant or combination of cryoprotectants which raises the glass transition temperature range of the sample. One or more dry protectants may be added to the cryosolution. The cryosolution is then nebulized and rapidly cooled with novel apparatus, dried by molecular distillation, stored and then rehydrated in a buffer prior to its use. The solutions comprise novel mixtures of cryoprotectants.
    Type: Grant
    Filed: November 14, 1996
    Date of Patent: July 14, 1998
    Assignee: Life Cell Corporation
    Inventors: Stephen A. Livesey, Anthony A. del Campo, Abhijit Nag, Ken B. Nichols, Carmen Piunno, David P. Ross
  • Method for processing and preserving collagen-based tissues for transplantation
    Patent number: 5336616
    Abstract: A method for processing and preserving an acellular collagen-based tissue matrix for transplantation is disclosed. The method includes the steps of processing biological tissues with a stabilizing solution to reduce procurement damage, treatment with a processing solution to remove cells, treatment with a cryoprotectant solution followed by freezing, drying, storage and rehydration under conditions that preclude functionally significant damage and reconstitution with viable cells.
    Type: Grant
    Filed: February 2, 1993
    Date of Patent: August 9, 1994
    Assignee: LifeCell Corporation
    Inventors: Stephen A. Livesey, Anthony A. del Campo, Abhijit Nag, Ken B. Nichols, Christopher Coleman