Patents by Inventor Ken Dower

Ken Dower has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inflammation treatment, detection and monitoring via TREM-1
    Publication number: 20080247955
    Abstract: The present invention provides methods of treating inflammatory diseases/disorders in a subject by inhibiting/antagonizing TREM-1 expression/activity/signal transduction and/or DAP12/TyroBP expression and/or activity. Methods of detecting the presence of inflammatory disease in a subject by detecting TREM-1 and/or DAP12/TyroBP expression and/or activity in the subject or a sample obtained therefrom, wherein increased expression or activity is indicative of the inflammatory disease are also included. The present invention further provides methods for assessing the efficacy of a TREM-1-modulating agent administered to a patient by detecting levels of secreted phosphoprotein 1 (SPP1) and/or one or more other biomarkers in the patient or in a sample from the patient.
    Type: Application
    Filed: January 16, 2008
    Publication date: October 9, 2008
    Inventors: Jun Kuai, Ken Dower, Jeffrey Lawrence Feldman, Debra Denene Pittman, Moitreyee Chatterjee-Kishore, David Gunther Winkler, Lih-Ling Lin, Scott Alan Jelinsky, Cara Williams