Patents by Inventor Ken Fukushi

Ken Fukushi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibody and method of immunological analysis of e-D-dimer and e-DD/E complex
    Patent number: 6132719
    Abstract: A monoclonal antibody which specifically reacts with D-monomer produced by digesting human fibrinogen with granulocyte elastase and D-domain containing digestion products produced by digesting human stabilized fibrin with granulocyte elastase, but does not react with fibrinogen, or fragment X, Y or E produced by digesting fibrinogen with granulocyte elastase is disclosed. The D-dimer or DD/E complex produced by digestion with granulocyte elastase in a sample from a living body can be analyzed without being interferred with fibrinogen, digestion products of fibrinogen with plasmin, or digestion products of stabilized fibrin with plasmin, using the monoclonal antibody.
    Type: Grant
    Filed: January 15, 1998
    Date of Patent: October 17, 2000
    Assignee: Iatron Laboratories, Inc.
    Inventors: Isao Kohno, Kimiko Inuzuka, Yumiko Ito, Ken Fukushi
  • Immunoassay, monoclonal antibody, and hybridoma
    Patent number: 5525476
    Abstract: The present invention relates to a method for determining a lipophilic compound, comprising using an antibody tolerant to one or more organic solvents, and carrying out an antigen-antibody reaction in the presence of one or more organic solvents. By the present method, it is possible to perform an antigen-antibody reaction of the lipophilic compound and the antibody, using an extract of a sample by one or more organic solvents, and thus the procedure becomes simple.Further, the present invention also relates to a monoclonal antibody specific to at least okadaic acid, dinophysistoxin-1 and dinophysistoxin-3, a hybridoma which produces the above monoclonal antibody, and an immunological determination method of diarrheal shellfish poisons using the above monoclonal antibody. According to the present invention, specific determination of all the three types of diarrheal shellfish poisons becomes possible.
    Type: Grant
    Filed: April 27, 1993
    Date of Patent: June 11, 1996
    Assignees: Iatron Laboratories, Inc., Osakafu
    Inventors: Shiro Matsuura, Yutaka Takagaki, Yonekazu Hamano, Ken Fukushi, Keigo Kabasawa, Hiroshi Kita