Abstract: The present invention relates to novel adenosine derivatives having the formula (I): ##STR1## wherein R is a lower alkyl group; R' is hydrogen or a lower alkyl group; X is a cycloalkyl group, an alkyl group having at least one hydroxy group, an alkyl group having at least one phenyl group, a bicycloalkyl group, a naphthylalkyl group, an acenaphthylenylalkyl group or a group of the formula (II) or (III); ##STR2## Z is hydrogen, a hydroxy group or a lower alkoxy group, Q is hydrogen or a hydroxy group, A is --CH.sub.2 --, --O--, --S-- or shows a direct connection; Y is --(CH.sub.2).sub.n -- or shows a direct connection; n is an integer of 1 to 3; and the broken line is a double bond or a single bond.and pharmaceutically acceptable salt thereof, which are useful as antihypertensive agents.

Abstract: Novel adenosine compounds of the formula (I): ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are hydrogen or a lower alkyl group; X is hydrogen, a lower alkyl group, an amino group or halogen; and Y is hydrogen or a lower alkyl group, exhibit utility as antihypertensive agents.

Abstract: The present invention relates to novel adenosine derivatives having the formula (I): wherein R is a lower alkyl group; R′ is hydrogen or a lower alkyl group; X is a cycloalkyl group, an alkyl group having at least one hydroxy group, an alkyl group having at least one phenyl group, a bicycloalkyl group, a naphthylalkyl group, an acenaphthylenylalkyl group or a group of the formula (II) or (III); Z is hydrogen, a hydroxy group or a lower alkoxy group, Q is hydrogen or a hydroxy group, A is —CH2—, —O—, —S— or shows a direct connection; Y is —(CH2)n— or shows a direct connection; n is an integer of 1 to 3; and the broken line is a double bond or a single bond. and pharmaceutically acceptable salt thereof, which are useful as antihypertensive agents.