Patents by Inventor Ken-ichi Yamamura

Ken-ichi Yamamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMANIZED MOUSE
    Publication number: 20150052625
    Abstract: The present invention provides embryonic stem cells obtainable from an embryo of an immunodeficient mouse which is deficient in both Rag2 and Jak3 genes by culture in the presence of a GSK3 inhibitor and an MEK inhibitor, as well as a transgenic mouse, which is created with the use of these embryonic stem cells.
    Type: Application
    Filed: March 27, 2012
    Publication date: February 19, 2015
    Applicants: Trans Genic Inc., National University Corporation Kumamoto University
    Inventors: Ken-ichi Yamamura, Kimi Araki, Seiji Okada, Akihiko Shimono
  • Trap vectors and gene trapping method by using the same
    Patent number: 8722408
    Abstract: A trap vector containing a loxP sequence composed of inverted repeat sequence 1, a spacer sequence and inverted repeat sequence 2 in this order, the loxP sequence being a mutant loxP wherein a part of the inverted repeat sequence 1 or 2 is mutated.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: May 13, 2014
    Assignee: Transgenic Inc.
    Inventors: Ken-ichi Yamamura, Kimi Araki
  • TRAP VECTORS AND GENE TRAPPING METHOD BY USING THE SAME
    Publication number: 20110117642
    Abstract: A trap vector containing a loxP sequence composed of inverted repeat sequence 1, a spacer sequence and inverted repeat sequence 2 in this order, the loxP sequence being a mutant loxP wherein a part of the inverted repeat sequence 1 or 2 is mutated.
    Type: Application
    Filed: January 10, 2011
    Publication date: May 19, 2011
    Inventors: Ken-ichi YAMAMURA, Kimi Araki
  • Trap vectors and gene trapping using the same
    Publication number: 20090202988
    Abstract: A trap vector containing a loxP sequence composed of inverted repeat sequence 1, a spacer sequence and inverted repeat sequence 2 in this order, the loxP sequence being a mutant loxP wherein a part of the inverted repeat sequence 1 or 2 is mutated.
    Type: Application
    Filed: October 12, 2007
    Publication date: August 13, 2009
    Applicant: TRANSGENIC INC.
    Inventors: Ken-ichi Yamamura, Kimi Araki
  • Trap vectors and gene trapping by using the same
    Patent number: 7312075
    Abstract: A trap vector containing a loxP sequence composed of inverted repeat sequence 1, a spacer sequence and inverted repeat sequence 2 in this order, the loxP sequence being a mutant loxP wherein a part of the inverted repeat sequence 1 or 2 is mutated.
    Type: Grant
    Filed: May 2, 2000
    Date of Patent: December 25, 2007
    Assignee: Transgenic Inc.
    Inventors: Ken-ichi Yamamura, Kimi Araki
  • Exogenous gene expression vector containing chick .beta.-actin gene promoter
    Patent number: 5811260
    Abstract: An expression vector for the expression of an exogenous gene in an animal cell, which contains a chick .beta.-actin gene promoter and a restriction enzyme site for incorporating an exogenous gene at the downstream of said promoter and a process for expressing an exogenous gene, which comprises incorporating said exogenous gene into the expression vector at the restriction enzyme site for incorporating the exogenous gene, introducing said vector into an animal cell and culturing the obtained transformed animal cell. The expression system of the present invention can be applied to an expression of any exogenous gene and has an extremely high expression efficiency and is applicable to a wide range of host cells, and hence can sufficiently be utilized for industrial-scale production of a useful material.
    Type: Grant
    Filed: June 23, 1989
    Date of Patent: September 22, 1998
    Assignee: Juridical Foundation The Chemo-Sero Therapeutic Research Institute
    Inventors: Junichi Miyazaki, Ken-ichi Yamamura, Masatake Araki, Hiroshi Yonemura, Chikateru Nozaki
  • Exogenous gene expression vector containing chick .beta.-actin gene promoter
    Patent number: 5770400
    Abstract: An expression vector for the expression of an exogenous gene in an animal cell, which contains a chick .beta.-actin gene promoter and a restriction enzyme site for incorporating an exogenous gene at the downstream of said promoter and a process for expressing an exogenous gene, which comprises incorporating said exogenous gene into the expression vector at the restriction enzyme site for incorporating the exogenous gene, introducing said vector into an animal cell and culturing the obtained transformed animal cell. The expression system of the present invention can be applied to an expression of any exogenous gene and has an extremely high expression efficiency and is applicable to a wide range of host cells, and hence can sufficiently be utilized for industrial-scale production of a useful material.
    Type: Grant
    Filed: March 10, 1997
    Date of Patent: June 23, 1998
    Assignee: Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
    Inventors: Junichi Miyazaki, Ken-ichi Yamamura, Masatake Araki, Hiroshi Yonemura, Chikateru Nozaki