Patents by Inventor Ken Kangyi Qian
Ken Kangyi Qian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11918623Abstract: A composition of tirzepatide, comprising an agent selected from NaCl and propylene glycol; and dibasic sodium phosphate is provided.Type: GrantFiled: May 10, 2022Date of Patent: March 5, 2024Assignee: Eli Lilly and CompanyInventors: Vincent John Corvari, Christopher Sears Minie, Dinesh Shyamdeo Mishra, Ken Kangyi Qian
-
Publication number: 20220273762Abstract: A composition of tirzepatide, comprising an agent selected from NaCl and propylene glycol; and dibasic sodium phosphate is provided.Type: ApplicationFiled: May 10, 2022Publication date: September 1, 2022Inventors: Vincent John CORVARI, Christopher Sears MINIE, Dinesh Shyamdeo MISHRA, Ken Kangyi QIAN
-
Patent number: 11357820Abstract: A composition of tirzepatide, comprising an agent selected from NaCl and propylene glycol; and dibasic sodium phosphate is provided.Type: GrantFiled: June 14, 2019Date of Patent: June 14, 2022Assignee: Eli Lilly and CompanyInventors: Vincent John Corvari, Christopher Sears Minie, Dinesh Shyamdeo Mishra, Ken Kangyi Qian
-
Publication number: 20220143187Abstract: The present invention relates to preserved, surfactant-containing pharmaceutical compositions that are suitable for parenteral administration.Type: ApplicationFiled: March 11, 2020Publication date: May 12, 2022Inventors: Dinesh Shyamdeo Mishra, Ken Kangyi Qian
-
Publication number: 20210161827Abstract: Described herein is a composition comprising microparticles of one or more taste-masked active pharmaceutical ingredient(s), rapidly-dispersing microgranules, and other optional, pharmaceutically acceptable excipients. The microparticles (crystals, granules, beads or pellets containing the active) are coated with a taste-masking membrane comprising a water-insoluble polymer and one or more gastrosoluble inorganic or organic pore-formers (practically insoluble in water and saliva, but soluble in an acidic buffer), exhibit acceptable taste-masking when placed in the oral cavity and provide rapid, substantially-complete release of the dose on entry into the stomach.Type: ApplicationFiled: February 16, 2021Publication date: June 3, 2021Inventors: Jin-Wang Lai, Gopi M. Venkatesh, Ken Kangyi Qian
-
Patent number: 10952971Abstract: There is provided a method for preparing an orally disintegrating tablet (ODT) composition comprising microparticles of one or more taste-masked active pharmaceutical ingredient(s), rapidly-dispersing microgranules, and other optional, pharmaceutically acceptable excipients wherein the ODT disintegrates on contact with saliva in the buccal cavity forming a smooth, easy-to-swallow suspension. Furthermore, the microparticles (crystals, granules, beads or pellets containing the active), coated with a taste-masking membrane comprising a water-insoluble polymer and one or more gastrosoluble inorganic or organic pore-formers (practically insoluble in water and saliva, but soluble in an acidic buffer), exhibit acceptable taste-masking when placed in the oral cavity and provide rapid, substantially-complete release of the dose on entry into the stomach.Type: GrantFiled: March 29, 2019Date of Patent: March 23, 2021Assignee: Adare Pharmaceuticals, Inc.Inventors: Jin-Wang Lai, Gopi M. Venkatesh, Ken Kangyi Qian
-
Publication number: 20190388502Abstract: A composition of tirzepatide, comprising an agent selected from NaCl and propylene glycol; and dibasic sodium phosphate is provided.Type: ApplicationFiled: June 14, 2019Publication date: December 26, 2019Inventors: Vincent John Corvari, Christopher Sears Minie, Dinesh Shyamdeo Mishra, Ken Kangyi Qian
-
Patent number: 10471017Abstract: There is provided a method for preparing an orally disintegrating tablet (ODT) composition comprising microparticles of one or more task-masked active pharmaceutical ingredient(s), rapidly-dispersing microgranules, and other optional, pharmaceutically acceptable excipients wherein the ODT disintegrates on contact with saliva in the buccal cavity forming a smooth, easy-to-swallow suspension. Furthermore, the microparticles (crystals, granules, beads or pellets containing the active), coated with a taste-masking membrane comprising a water-insoluble polymer and one or more gastrosoluble inorganic or organic pore-formers (practically insoluble in water and saliva, but soluble in an acidic buffer), exhibit acceptable taste-masking when placed in the oral cavity and provide rapid, substantially-complete release of the dose on entry into the stomach.Type: GrantFiled: December 21, 2016Date of Patent: November 12, 2019Assignee: ADARE PHARMACEUTICALS, INC.Inventors: Jin-Wang Lai, Gopi M. Venkatesh, Ken Kangyi Qian
-
Publication number: 20190290591Abstract: There is provided a method for preparing an orally disintegrating tablet (ODT) composition comprising microparticles of one or more taste-masked active pharmaceutical ingredient(s), rapidly-dispersing microgranules, and other optional, pharmaceutically acceptable excipients wherein the ODT disintegrates on contact with saliva in the buccal cavity forming a smooth, easy-to-swallow suspension. Furthermore, the microparticles (crystals, granules, beads or pellets containing the active), coated with a taste-masking membrane comprising a water-insoluble polymer and one or more gastrosoluble inorganic or organic pore-formers (practically insoluble in water and saliva, but soluble in an acidic buffer), exhibit acceptable taste-masking when placed in the oral cavity and provide rapid, substantially-complete release of the dose on entry into the stomach.Type: ApplicationFiled: March 29, 2019Publication date: September 26, 2019Inventors: Jin-Wang LAI, Gopi M. Venkatesh, Ken Kangyi Qian
-
Patent number: 9730896Abstract: A tablet that rapidly disintegrates in the oral cavity comprising a compressed blend of rapidly dispersing microgranules prepared by granulating a sugar alcohol or a saccharide or a mixture thereof having an average particle size less than about 30 microns and a disintegrant, and a taste-masked microcapsule containing at least one drag, the microcapsule being prepared by granulating a pharmaceutically acceptable formulation comprising at least one drug in a therapeutically effective amount and at least one polymeric binder that improves resilience of the microgranules, wet milling the granulated mass, and microencapsulating the milled granules to provide microcapsules.Type: GrantFiled: June 18, 2015Date of Patent: August 15, 2017Assignee: ADARE PHARMACEUTICALS, INC.Inventors: Gopi M Venkatesh, Ken Kangyi Qian, Shyam Vangala, James M Clevenger, Donald Guenther
-
Publication number: 20170105942Abstract: There is provided a method for preparing an orally disintegrating tablet (ODT) composition comprising microparticles of one or more task-masked active pharmaceutical ingredient(s), rapidly-dispersing microgranules, and other optional, pharmaceutically acceptable excipients wherein the ODT disintegrates on contact with saliva in the buccal cavity forming a smooth, easy-to-swallow suspension. Furthermore, the microparticles (crystals, granules, beads or pellets containing the active), coated with a taste-masking membrane comprising a water-insoluble polymer and one or more gastrosoluble inorganic or organic pore-formers (practically insoluble in water and saliva, but soluble in an acidic buffer), exhibit acceptable taste-masking when placed in the oral cavity and provide rapid, substantially-complete release of the dose on entry into the stomach.Type: ApplicationFiled: December 21, 2016Publication date: April 20, 2017Applicant: Adare Pharmaceuticals, Inc.Inventors: Jin-Wang LAI, Gopi M. Venkatesh, Ken Kangyi Qian
-
Publication number: 20150283085Abstract: A tablet that rapidly disintegrates in the oral cavity comprising a compressed blend of rapidly dispersing microgranules prepared by granulating a sugar alcohol or a saccharide or a mixture thereof having an average particle size less than about 30 microns and a disintegrant, and a taste-masked microcapsule containing at least one drag, the microcapsule being prepared by granulating a pharmaceutically acceptable formulation comprising at least one drug in a therapeutically effective amount and at least one polymeric binder that improves resilience of the microgranules, wet milling the granulated mass, and microencapsulating the milled granules to provide microcapsules.Type: ApplicationFiled: June 18, 2015Publication date: October 8, 2015Inventors: Gopi M. VENKATESH, Ken Kangyi QIAN, Shyam VANGALA, James M. CLEVENGER, Donald GUENTHER
-
Patent number: 9089490Abstract: A tablet that rapidly disintegrates in the oral cavity comprising a compressed blend of rapidly dispersing microgranules prepared by granulating a sugar alcohol or a saccharide or a mixture thereof having an average particle size less than about 30 microns and a disintegrant, and a taste-masked microcapsule containing at least one drug, the microcapsule being prepared by granulating a pharmaceutically acceptable formulation comprising at least one drug in a therapeutically effective amount and at least one polymeric binder that improves resilience of the microgranules, wet milling the granulated mass, and microencapsulating the milled granules to provide microcapsules.Type: GrantFiled: August 23, 2013Date of Patent: July 28, 2015Assignee: Aptalis Pharmatech, Inc.Inventors: Gopi M Venkatesh, Ken Kangyi Qian, Shyam Vangala, James M Clevenger, Donald Guenther
-
Publication number: 20140170215Abstract: A tablet that rapidly disintegrates in the oral cavity comprising a compressed blend of rapidly dispersing microgranules prepared by granulating a sugar alcohol or a saccharide or a mixture thereof having an average particle size less than about 30 microns and a disintegrant, and a taste-masked microcapsule containing at least one drug, the microcapsule being prepared by granulating a pharmaceutically acceptable formulation comprising at least one drug in a therapeutically effective amount and at least one polymeric binder that improves resilience of the microgranules, wet milling the granulated mass, and microencapsulating the milled granules to provide microcapsules.Type: ApplicationFiled: August 23, 2013Publication date: June 19, 2014Inventors: Gopi M. VENKATESH, Ken Kangyi Qian, Shyam Vangala, James M. Clevenger, Donald Guenther
-
Patent number: 8545881Abstract: A tablet that rapidly disintegrates in the oral cavity comprising a compressed blend of rapidly dispersing microgranules prepared by granulating a sugar alcohol or a saccharide or a mixture thereof having an average particle size less than about 30 microns and a disintegrant, and a taste-masked microcapsule containing at least one drug, the microcapsule being prepared by granulating a pharmaceutically acceptable formulation comprising at least one drug in a therapeutically effective amount and at least one polymeric binder that improves resilience of the microgranules, wet milling the granulated mass, and microencapsulating the milled granules to provide microcapsules.Type: GrantFiled: April 19, 2004Date of Patent: October 1, 2013Assignee: Eurand Pharmaceuticals, Ltd.Inventors: Gopi M. Venkatesh, Ken Kangyi Qian, Shyam Vangala, James M. Clevenger, Donald Guenther
-
Publication number: 20090263480Abstract: There is provided a method for preparing an orally disintegrating tablet (ODT) composition comprising microparticles of one or more taste-masked active pharmaceutical ingredients, rapidly-dispersing microgranules, and other optional, pharmaceutically acceptable excipients wherein the ODT disintegrates rapidly with saliva in the buccal cavity forming a smooth, easy-to-swallow suspension. Furthermore, the microparticles (crystals, granules, beads or pellets containing one or more actives) with a taste-masking membrane applied by a modified solvent coacervation process comprising a water-insoluble polymer and at least one gastrosoluble inorganic or organic pore-former, exhibit a pleasant taste when placed in the oral cavity and provide rapid, substantially-complete release of the dose on entry into the stomach.Type: ApplicationFiled: May 15, 2009Publication date: October 22, 2009Inventors: Jin-Wang Lai, Ken Kangyi Qian, Gopi M. Venkatesh