Abstract: This disclosure describes low frequency non-separable transform and multiple transform selection deadlock prevention. The systems and methods may allow for types of transforms performed on the encoding side of a video encoding and decoding system to be determined prior to the transform parameters being decoded on the decoder side. This may allow for the inverse transform of some or all transform units (TU) received in a bit stream to be performed quicker, which may reduce the stress on the bit stream buffer.

Abstract: The present disclosure provides for compositions and methods for identifying peptide classifiers. In one embodiment, a peptide classifier for diagnosing rheumatoid arthritis includes a composition comprising a plurality of molecules. Each molecule comprises a peptide having a sequence selected from SEQ ID NOS: 1-8861, wherein the plurality of molecules defines a classifier for rheumatoid arthritis.

Abstract: The present invention provides a method for identifying a synthetic classifier including contacting at least a first and second samples derived from different groups of a cohort with a first plurality of peptides. The first plurality of peptides includes a first subset of peptides defining at least one naturally occurring amino acid sequence, and a second subset of peptides defining a plurality of variants of the first subset of peptides. The plurality of variants includes, for each one of the first subset of peptides, a variant peptide having at least one of a substitution, a deletion, an insertion, an extension, and a modification. The method further includes selecting at least one of the plurality of variants from the second subset of peptides, and defining a synthetic classifier including the at least one of the plurality of variants that distinguishes between samples derived from the first and second cohorts.

Abstract: The present invention provides a method for identifying a synthetic classifier including contacting at least a first and second samples derived from different groups of a cohort with a first plurality of peptides. The first plurality of peptides includes a first subset of peptides defining at least one naturally occurring amino acid sequence, and a second subset of peptides defining a plurality of variants of the first subset of peptides. The plurality of variants includes, for each one of the first subset of peptides, a variant peptide having at least one of a substitution, a deletion, an insertion, an extension, and a modification. The method further includes selecting at least one of the plurality of variants from the second subset of peptides, and defining a synthetic classifier including the at least one of the plurality of variants that distinguishes between samples derived from the first and second cohorts.

Abstract: The present invention provides a method for identifying a synthetic classifier including contacting at least a first and second samples derived from different groups of a cohort with a first plurality of peptides. The first plurality of peptides includes a first subset of peptides defining at least one naturally occurring amino acid sequence, and a second subset of peptides defining a plurality of variants of the first subset of peptides. The plurality of variants includes, for each one of the first subset of peptides, a variant peptide having at least one of a substitution, a deletion, an insertion, an extension, and a modification. The method further includes selecting at least one of the plurality of variants from the second subset of peptides, and defining a synthetic classifier including the at least one of the plurality of variants that distinguishes between samples derived from the first and second cohorts.

Abstract: A universal bong lid adaptor system including an adaptor assembly having a flexible body, a mouthpiece, an opening, and a tubular member having a first-end and a second-end. The adaptor assembly includes the flexible body configured to engage a top lip of a container with the tubular member extending downwardly into the container and the mouthpiece extending upwardly from the container. The device allows a user to transform a container into a smoking device for smoking smokable material.

Abstract: The present disclosure provides a method of identifying a peptide antigen, including: contacting an antibody-comprising composition to a peptide microarray having an array surface and a plurality of feature pairs disposed thereon. Each of the feature pairs includes a first feature of wild-type peptides having a defined sequence and a second feature of mutant peptides having the defined sequence with a single amino acid mutation. Each of the wild-type peptides and the mutant peptides has an array-coupled terminus coupled to the array surface and an opposing free terminus, and the position of the amino acid mutation in the mutant peptides is located closer to the array-coupled terminus of the mutant peptides than tire free terminus. The method further includes detecting binding of an antibody in the antibody-comprising composition to at least one of the feature pairs on the peptide microarray, and identifying feature pairs exhibiting differential binding.

Abstract: The present disclosure provides a method of identifying a peptide antigen, including contacting an antibody-comprising composition to a peptide microarray having an array surface and a plurality of feature pairs disposed thereon. Each of the feature pairs includes a first feature of wild-type peptides having a defined sequence and a second feature of mutant peptides having the defined sequence with a single amino acid mutation. Each of the wild-type peptides and the mutant peptides has an array-coupled terminus coupled to the array surface and an opposing free terminus, and the position of the amino acid mutation in the mutant peptides is located closer to the array-coupled terminus of the mutant peptides than the free terminus. The method further includes detecting binding of an antibody in the antibody-comprising composition to at least one of the feature pairs on the peptide microarray, and identifying feature pairs exhibiting differential binding.

Abstract: The present invention provides a method for identifying a synthetic classifier including contacting at least a first and second samples derived from different groups of a cohort with a first plurality of peptides. The first plurality of peptides includes a first subset of peptides defining at least one naturally occurring amino acid sequence, and a second subset of peptides defining a plurality of variants of the first subset of peptides. The plurality of variants includes, for each one of the first subset of peptides, a variant peptide having at least one of a substitution, a deletion, an insertion, an extension, and a modification. The method further includes selecting at least one of the plurality of variants from the second subset of peptides, and defining a synthetic classifier including the at least one of the plurality of variants that distinguishes between samples derived from the first and second cohorts.

Abstract: The present disclosure provides a method of identifying a peptide antigen, including contacting an antibody-comprising composition to a peptide microarray having an array surface and a plurality of feature pairs disposed thereon. Each of the feature pairs includes a first feature of wild-type peptides having a defined sequence and a second feature of mutant peptides having the defined sequence with a single amino acid mutation. Each of the wild-type peptides and the mutant peptides has an array-coupled terminus coupled to the array surface and an opposing free terminus, and the position of the amino acid mutation in the mutant peptides is located closer to the array-coupled terminus of the mutant peptides than the free terminus. The method further includes detecting binding of an antibody in the antibody-comprising composition to at least one of the feature pairs on the peptide microarray, and identifying feature pairs exhibiting differential binding.

Abstract: The invention is a method of separating full-length oligonucleotide products from shorter synthesis by-products by using mRNA display and affinity purification followed by recovery and amplification of the selected oligonucleotide.

Abstract: Methods and computer-readable media are provided for presenting on a website a single video stream that includes a plurality of preview videos directed toward a particular category of interest to a user. Informational items, such as news stories, that have associated preview videos are selected from a database. A preview video for each of the informational items is then algorithmically determined using, for instance, a ranking system. The ranking system may be based on a variety of heuristics, which may indicate popularity, importance, reliability, or relevance of the specific preview video. The single video stream is presented on the website such that the preview videos can be viewed as an assembled sequence of videos. Once an indication has been received to initiate play of the video stream, the preview videos play without requiring any user interaction.

Abstract: Automatic identification and authentication of a user of a mobile application entails receiving from the wireless communications device a unique device identifier and an e-mail address corresponding to the wireless communications device, associating a registration identifier with the unique device identifier and the e-mail address, generating an authentication token, and communicating the authentication token and the registration identifier to the wireless communications device. This technology obviates the need for the user to remember and enter a user ID and password to access backed-up application data on a server. This is particularly useful for instant messaging applications, e.g. PIN messaging, in which the unique device identifier is used to identify the user and is also the transport address. Once registered, the user who has switched to a new device or has wiped his existing device, can restore contacts or other application data from the server based on the registration identifier.

Abstract: Automatic identification and authentication of a user of a mobile application entails receiving from the wireless communications device a unique device identifier and an e-mail address corresponding to the wireless communications device, associating a registration identifier with the unique device identifier and the e-mail address, generating an authentication token, and communicating the authentication token and the registration identifier to the wireless communications device. This technology obviates the need for the user to remember and enter a user ID and password to access backed-up application data on a server. This is particularly useful for instant messaging applications, e.g. PIN messaging, in which the unique device identifier is used to identify the user and is also the transport address. Once registered, the user who has switched to a new device or has wiped his existing device, can restore contacts or other application data from the server based on the registration identifier.

Abstract: Methods and computer-readable media are provided for presenting on a website a single video stream that includes a plurality of preview videos directed toward a particular category of interest to a user. Informational items, such as news stories, that have associated preview videos are selected from a database. A preview video for each of the informational items is then algorithmically determined using, for instance, a ranking system. The ranking system may be based on a variety of heuristics, which may indicate popularity, importance, reliability, or relevance of the specific preview video. The single video stream is presented on the website such that the preview videos can be viewed as an assembled sequence of videos. Once an indication has been received to initiate play of the video stream, the preview videos play without requiring any user interaction.