Patents by Inventor Ken M. Kosack

Ken M. Kosack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Activated nitric oxide donors and methods of making and using thereof
    Patent number: 9439915
    Abstract: Described herein are compositions useful in anticancer treatment. The compositions are composed of (a) an O2-aryl substituted diazeniumdiolate and (b) an amphiphile, wherein the amount of amphiphile is sufficient to produce a liposome or micelle. The compositions described herein provide numerous advantages such as increased solubility and stability of the O2-aryl substituted diazeniumdiolate in vivo. The compositions also do not induce hypotension. Methods for using the compositions in anticancer treatment are also described herein.
    Type: Grant
    Filed: April 13, 2015
    Date of Patent: September 13, 2016
    Assignee: University of Utah Research Foundation
    Inventors: Paul J. Shami, Ken M. Kosack
  • ACTIVATED NITRIC OXIDE DONORS AND METHODS OF MAKING AND USING THEREOF
    Publication number: 20150290224
    Abstract: Described herein are compositions useful in anticancer treatment and prevention. The compositions are composed of (a) an O2-aryl substituted diazeniumdiolate and (b) an amphiphile, wherein the amount of amphiphile is sufficient to produce a liposome or micelle. The compositions described herein provide numerous advantages such as increased solubility and stability of the O2-aryl substituted diazeniumdiolate in vivo. The compositions also do not induce hypotension. Methods for using the compositions in anticancer treatment and prevention are also described herein.
    Type: Application
    Filed: April 13, 2015
    Publication date: October 15, 2015
    Applicant: University of Utah Research Foundation
    Inventors: Paul J. Shami, Ken M. Kosack