Patents by Inventor Ken M. Kosak

Ken M. Kosak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Activated nitric oxide donors and methods of making and using thereof
    Patent number: 9005656
    Abstract: Described herein are compositions useful in anticancer treatment and prevention. The compositions are composed of (a) an O2-aryl substituted diazeniumdiolate and (b) an amphiphile, wherein the amount of amphiphile is sufficient to produce a liposome or micelle. The compositions described herein provide numerous advantages such as increased solubility and stability of the O2-aryl substituted diazeniumdiolate in vivo. The compositions also do not induce hypotension. Methods for using the compositions in anticancer treatment and prevention are also described herein.
    Type: Grant
    Filed: March 5, 2009
    Date of Patent: April 14, 2015
    Assignee: University of Utah Research Foundation
    Inventors: Paul J. Shami, Ken M. Kosak
  • DITHIOCARBAMATE METAL CHELATES AND METHODS OF MAKING AND USING THEREOF
    Publication number: 20110206756
    Abstract: Described herein are compositions useful in anticancer treatment and prevention. The compositions are composed of (a) a dithiocarbamate metal chelate and (b) an amphiphile, wherein the amount of amphiphile is sufficient to produce a liposome or micelle. Methods for using the compositions in anticancer treatment and prevention are also described herein.
    Type: Application
    Filed: March 16, 2009
    Publication date: August 25, 2011
    Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Paul J. Shami, Ken M. Kosak, Thomas Kennedy
  • ACTIVATED NITRIC OXIDE DONORS AND METHODS OF MAKING AND USING THEREOF
    Publication number: 20110182978
    Abstract: Described herein are compositions useful in anticancer treatment and prevention. The compositions are composed of (a) an O2-aryl substituted diazeniumdiolate and (b) an amphiphile, wherein the amount of amphiphile is sufficient to produce a liposome or micelle. The compositions described herein provide numerous advantages such as increased solubility and stability of the O2-aryl substituted diazeniumdiolate in vivo. The compositions also do not induce hypotension. Methods for using the compositions in anticancer treatment and prevention are also described herein.
    Type: Application
    Filed: March 5, 2009
    Publication date: July 28, 2011
    Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Paul J. Shami, Ken M. Kosak