Patents by Inventor Ken Mizushima

Ken Mizushima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120184545
    Abstract: The present invention relates to an agent which slows down the heart rate which has an excellent controlling ability in diagnostic imaging comprising a short-acting ?-blocker (e.g. landiolol hydrochloride or esmolol hydrochloride). The short-acting ?-blocker has a property of slowing down the heart rate and it can temporarily suppress the tachycardia at diagnosis. According to the dose and the method of administration, it can control the period for the heart rate adjustment. Also, the present invention relates to a diagnostic imaging auxiliary comprising a short-acting ?-blocker as active ingredient.
    Type: Application
    Filed: March 28, 2012
    Publication date: July 19, 2012
    Applicant: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Masaharu HIRANO, Kenzo Nakao, Ken Mizushima, Morito Akisada, Takahiro Azuma
  • Patent number: 7928143
    Abstract: The invention relates to a neurodegenerative disease treating agent for parenteral use, which comprises (2R)-2-propyloctanoic acid or a salt thereof. Since the neurodegenerative disease treating agent of the present invention comprising (2R)-2-propyloctanoic acid or a salt thereof, characterized in that a dosage exceeding about 100 mg per dose is parenterally administered, shows neuropathy improving effect and S-100? increase inhibiting effect in patients with cerebral infarction, it is useful for the treatment of neurodegenerative diseases including cerebral infarction. In addition, it is also useful as a neural regeneration agent after transplantation.
    Type: Grant
    Filed: October 1, 2004
    Date of Patent: April 19, 2011
    Assignee: Ono Pharmaceutical Co., Ltd.
    Inventors: Yosuke Funakoshi, Ken Mizushima, Toshio Takakuwa
  • Publication number: 20070249695
    Abstract: The present invention relates to preventive and/or therapeutic agents for Meniere's disease, which comprise a leukotriene antagonist (such as pranlukast hydrate) as an active ingredient. Leukotriene antagonists (such as pranlukast hydrate) are effective in ameliorating various symptoms, such as hearing impairment, tinnitus, a feeling of fullness in the ear and vertigo, thus being useful as a preventive and/or therapeutic agent for Meniere's disease.
    Type: Application
    Filed: June 29, 2005
    Publication date: October 25, 2007
    Inventors: Kazuya Kawata, Kenzo Nakao, Ken Mizushima, Shozo Matsuoka
  • Publication number: 20070043116
    Abstract: The invention relates to a neurodegenerative disease treating agent for parenteral use, which comprises (2R)-2-propyloctanoic acid or a salt thereof. Since the neurodegenerative disease treating agent of the present invention comprising (2R)-2-propyloctanoic acid or a salt thereof, characterized in that a dosage exceeding about 100 mg per dose is parenterally administered, shows neuropathy improving effect and S-100 ? increase inhibiting effect in patients with cerebral infarction, it is useful for the treatment of neurodegenerative diseases including cerebral infarction. In addition, it is also useful as a neural regeneration agent after transplantation.
    Type: Application
    Filed: October 1, 2004
    Publication date: February 22, 2007
    Inventors: Yosuke Funakoshi, Ken Mizushima, Toshio Takakuwa
  • Publication number: 20060286037
    Abstract: The present invention relates to an agent which slows down the heart rate which has an excellent controlling ability in diagnostic imaging comprising a short-acting ?-blocker (e.g. landiolol hydrochloride or esmolol hydrochloride). The short-acting ?-blocker has a property of slowing down the heart rate and it can temporarily suppress the tachycardia at diagnosis. According to the dose and the method of administration, it can control the period for the heart rate adjustment. Also, the present invention relates to a diagnostic imaging auxiliary comprising a short-acting ?-blocker as active ingredient.
    Type: Application
    Filed: August 6, 2004
    Publication date: December 21, 2006
    Inventors: Masaharu Hirano, Kenzo Nakao, Ken Mizushima, Morito Akisada, Takahiro Azuma