Patents by Inventor Ken NARUSE

Ken NARUSE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND SYSTEMS FOR DEVELOPING MEDIA FOR EXTRACELLULAR VESICLE PRODUCTION
    Publication number: 20260022342
    Abstract: The present disclosure relates generally to methods and systems for the analysis, development, testing, and/or optimization, of culture media and/or culture conditions for extracellular vesicle production; culture media analyzed, developed, tested, and/or optimized via such assays; and to extracellular vesicles and compositions comprising extracellular vesicles generated using such culture media.
    Type: Application
    Filed: May 24, 2023
    Publication date: January 22, 2026
    Applicants: FUJIFILM Holdings America Corporation, FUJIFILM Irvine Scientific, Inc.
    Inventors: Ken NARUSE, Cassandra WRIGHT BELLVER, Alison FUJII, Aaron FULTON, Richard A. FESTA, Matthew TENORIO, David T. HO, Nisa RENAULT, Michele HAMRICK, Jacquelyn WONG, Robert E. NEWMAN, Maria Katerina R. VILLAFUERTE
  • Tim protein-bound carrier, methods for obtaining, removing and detecting extracellular membrane vesicles and viruses using said carrier, and kit including said carrier
    Patent number: 11639924
    Abstract: The invention provides a carrier and a method for obtaining, removing, or detecting extracellular membrane vesicle or virus present in a sample. In particular, the invention provides (a) a carrier (a Tim carrier) on which a protein (a Tim protein), selected from a T-cell immunoglobulin and mucin domain-containing molecule-4 (a Tim-4) protein, a Tim-3 protein, and a Tim-1 protein, is bound; (b) a method for obtaining the extracellular membrane vesicle or the virus in the sample; (c) a method for removing the extracellular membrane vesicle or the virus in the sample; (d) a method for detecting the extracellular membrane vesicle or the virus in the sample; (e) a kit for capturing the extracellular membrane vesicle or the virus, comprising the Tim carrier; and (f) a kit for capturing the extracellular membrane vesicle or the virus, comprising a reagent containing the Tim protein and a reagent containing the carrier.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: May 2, 2023
    Assignees: FUJIFILM CORPORATION, OSAKA UNIVERSITY
    Inventors: Takahiro Nishibu, Naoko Imawaka, Ken Naruse, Rikinari Hanayama
  • TIM PROTEIN-BOUND CARRIER, METHODS FOR OBTAINING, REMOVING AND DETECTING EXTRACELLULAR MEMBRANE VESICLES AND VIRUSES USING SAID CARRIER, AND KIT INCLUDING SAID CARRIER
    Publication number: 20200393449
    Abstract: The invention provides a carrier and a method for obtaining, removing, or detecting extracellular membrane vesicle or virus present in a sample. In particular, the invention provides (a) a carrier (a Tim carrier) on which a protein (a Tim protein), selected from a T-cell immunoglobulin and mucin domain-containing molecule-4 (a Tim-4) protein, a Tim-3 protein, and a Tim-1 protein, is bound; (b) a method for obtaining the extracellular membrane vesicle or the virus in the sample; (c) a method for removing the extracellular membrane vesicle or the virus in the sample; (d) a method for detecting the extracellular membrane vesicle or the virus in the sample; (e) a kit for capturing the extracellular membrane vesicle or the virus, comprising the Tim carrier; and (f) a kit for capturing the extracellular membrane vesicle or the virus, comprising a reagent containing the Tim protein and a reagent containing the carrier.
    Type: Application
    Filed: August 27, 2020
    Publication date: December 17, 2020
    Applicants: FUJIFILM WAKO PURE CHEMICAL CORPORATION, OSAKA UNIVERSITY
    Inventors: Takahiro NISHIBU, Naoko IMAWAKA, Ken NARUSE, Rikinari HANAYAMA
  • Tim protein-bound carrier, methods for obtaining, removing and detecting extracellular membrane vesicles and viruses using said carrier, and kit including said carrier
    Patent number: 10794899
    Abstract: The invention provides a carrier and a method for obtaining, removing, or detecting extracellular membrane vesicle or virus present in a sample. In particular, the invention provides (a) a carrier (a Tim carrier) on which a protein (a Tim protein), selected from a T-cell immunoglobulin and mucin domain-containing molecule-4 (a Tim-4) protein, a Tim-3 protein, and a Tim-1 protein, is bound; (b) a method for obtaining the extracellular membrane vesicle or the virus in the sample; (c) a method for removing the extracellular membrane vesicle or the virus in the sample; (d) a method for detecting the extracellular membrane vesicle or the virus in the sample; (e) a kit for capturing the extracellular membrane vesicle or the virus, comprising the Tim carrier; and f) a kit for capturing the extracellular membrane vesicle or the virus, comprising a reagent containing the Tim protein and a reagent containing the carrier.
    Type: Grant
    Filed: November 27, 2015
    Date of Patent: October 6, 2020
    Assignees: FUJIFILM WAKO PURE CHEMICAL CORPORATION, OSAKA UNIVERSITY
    Inventors: Takahiro Nishibu, Naoko Imawaka, Ken Naruse, Rikinari Hanayama
  • TIM PROTEIN-BOUND CARRIER, METHODS FOR OBTAINING, REMOVING AND DETECTING EXTRACELLULAR MEMBRANE VESICLES AND VIRUSES USING SAID CARRIER, AND KIT INCLUDING SAID CARRIER
    Publication number: 20180120299
    Abstract: The invention provides a carrier and a method for obtaining, removing, or detecting extracellular membrane vesicle or virus present in a sample. In particular, the invention provides (a) a carrier (a Tim carrier) on which a protein (a Tim protein), selected from a T-cell immunoglobulin and mucin domain-containing molecule-4 (a Tim-4) protein, a Tim-3 protein, and a Tim-1 protein, is bound; (b) a method for obtaining the extracellular membrane vesicle or the virus in the sample; (c) a method for removing the extracellular membrane vesicle or the virus in the sample; (d) a method for detecting the extracellular membrane vesicle or the virus in the sample; (e) a kit for capturing the extracellular membrane vesicle or the virus, comprising the Tim carrier; and f) a kit for capturing the extracellular membrane vesicle or the virus, comprising a reagent containing the Tim protein and a reagent containing the carrier.
    Type: Application
    Filed: November 27, 2015
    Publication date: May 3, 2018
    Applicants: WAKO PURE CHEMICAL INDUSTRIES, LTD., OSAKA UNIVERSITY
    Inventors: Takahiro NISHIBU, Naoko IMAWAKA, Ken NARUSE, Rikinari HANAYAMA