Abstract: The present invention relates to a method of editing a filamentous fungal genome by direct introduction of a genome editing protein molecule or complex. The method includes three modes. In the first mode, a genome editing protein molecule or complex for a target gene is directly introduced into a cell of an Aspergillus fungus, to edit a gene in the Aspergillus fungal genome. In the second mode, a genome editing protein molecule or complex for a target region in a filamentous fungal genome, and a desired DNA fragment, are directly introduced into a filamentous fungal cell, to knock-in the DNA fragment to a desired target site in the filamentous fungal genome. In the third mode, genome editing protein molecules or complexes for plural target genes are directly introduced into a filamentous fungal cell, to carry out simultaneous editing of the plural genes in the filamentous fungal genome.

Abstract: The present invention relates to a method of editing a filamentous fungal genome by direct introduction of a genome editing protein molecule or complex. The method includes three modes. In the first mode, a genome editing protein molecule or complex for a target gene is directly introduced into a cell of an Aspergillus fungus, to edit a gene in the Aspergillus fungal genome. In the second mode, a genome editing protein molecule or complex for a target region in a filamentous fungal genome, and a desired DNA fragment, are directly introduced into a filamentous fungal cell, to knock-in the DNA fragment to a desired target site in the filamentous fungal genome. In the third mode, genome editing protein molecules or complexes for plural target genes are directly introduced into a filamentous fungal cell, to carry out simultaneous editing of the plural genes in the filamentous fungal genome.

Abstract: A high-speed differential cable (1) comprises two-core signal lines in each of which a first dielectric layer (12) is provided around the perimeter of an internal conductor (11), which are arranged so that the cores thereof are in parallel, a second dielectric layer (13) provided around the perimeter of the two-core signal lines, drain lines (14) which are disposed outside the second dielectric layer and at both sides of the two-core signal lines, respectively, and arranged in parallel to the signal lines, an external conductor (15) which is provided longitudinally around the perimeter of the second dielectric layer and the drain lines, with the insulative side thereof arranged outside and the conductive side thereof arranged inside, a casing (16) provided around the perimeter of the external conductor, and drain line trenches (17) provided at the perimeter of the second dielectric layer, where the drain lines are disposed.

Abstract: Perfluorotripentylamine, perfluoropolyether or another such high-boiling liquid is added as a foaming agent to a thermoplastic fluororesin such as a tetrafluoroethylene-perfluoroalkyl vinyl ether copolymer resin or a tetrafluoroethylene-hexafluoropropylene copolymer resin. Because the vapor pressure of said foaming agent in the molten fluororesin is lower than that of Freon or another such low-boiling foaming agent, the cells in the foam can be made fine and uniform in diameter.