Abstract: A fluorescence polarization measurement device includes a light source unit, a polarization direction modulation element, a detector, and a controller. The polarization direction modulation element spatially modulates a polarization direction of the excitation light by a predetermined frequency, and emits, on a measurement target solution, the excitation light for which the polarization direction is spatially modulated by the predetermined frequency. The detector detects a spatial distribution of fluorescence intensity of the fluorescence having a polarization direction in a predetermined direction from among fluorescence emitted from the measurement target solution due to the excitation light.

Abstract: A light ray direction control element includes a first light transmitting substrate, a second light transmitting substrate facing the first light transmitting substrate, a first light transmitting region provided on a first main surface of the first light transmitting substrate, a second light transmitting region provided on a first main surface of the second light transmitting substrate, first light absorbing regions positioned among the first light transmitting region, and second light absorbing regions positioned among the second light transmitting region. The light ray direction control element further includes a light transmitting dispersion medium enclosed in the first light absorbing regions and the second light absorbing regions, and charged electrophoretic particles dispersed in the light transmitting dispersion medium.

Abstract: A microdevice includes: a microchannel to which a measurement target solution containing a measurement target substance is introduced; an antibody being fixed to at least one sidewall surface of the microchannel and specifically binding to the measurement target substance; a fluorescence-labeled derivative being specifically bound to the antibody and being acquired by fluorescence-labeling the measurement target substance; and a light blocker blocking excitation light exciting fluorescent light radiated by the fluorescence-labeled derivative. The measurement target substance and the fluorescence-labeled derivative specifically bind to the antibody in a competitive manner, and the antibody is fixed to the sidewall surface of the microchannel in a state of specifically binding to the fluorescence-labeled derivative. The light blocker blocks the excitation light entering the fluorescence-labeled derivative specifically binding to the antibody.

Abstract: A polarization modulation element includes N twisted nematic liquid crystal cells (where N is an integer of 3 or greater) for which a twist direction is identical. A sum of a twist angle of each of the twisted nematic liquid crystal cells is 90°. In at least one of the twisted nematic liquid crystal cells that are adjacent, the alignment axis direction of the light emitting-side substrate and the alignment axis direction of the light incident-side substrate are orthogonal to each other. In the other twisted nematic liquid crystal cells that are adjacent, the alignment axis direction of the light emitting-side substrate and the alignment axis direction of the light incident-side substrate match.

Abstract: A degree of polarization of second reference samples produced by adding an antibody, a tracer, and a target substance having mutually different concentrations to a first reference sample not including the target substance is corrected with a degree of polarization of the first reference sample to generate a first calibration curve. A degree of polarization of a second sample to be measured produced by adding the antibody and the tracer to a first sample to be measured in amounts equal to those added to the second reference samples is corrected with a degree of polarization of the first sample to be measured to obtain the concentration of the target substance in the first calibration curve.

Abstract: A substance separating device includes a reaction vessel provided with an interior that is partitioned into a first chamber and a second chamber by a dialysis membrane, a solution being stored in the reaction vessel. A specimen is stored in the first chamber, and dye-modified molecule that has a binding ability for specifically binding to a substance to be measured having a molecular weight greater than a molecular weight cut-off the dialysis membrane is stored in at least one of the first chamber and the second chamber. The dye-modified molecule has a molecular weight that is less than the molecular weight cut-off of the dialysis membrane.

Abstract: A concentration estimation kit includes a derivatization reagent that derivatizes at least a portion of an antigen included in a mixed specimen, and that is for obtaining a plurality of samples having different derivatization rates, the derivatization rate being a ratio of a derivatized antigen relative to the antigen included in the specimen; an antibody that binds to the antigen; and the antigen modified with a dye.

Abstract: A light ray direction control element includes a base, a plurality of light transmitting layers arranged on a main surface of the base, a light absorbing layer disposed among the plurality of light transmitting layers, and a tilt prevention layer provided on the main surface of the base and disposed on an outer periphery of a region in which the plurality of light transmitting layers is disposed.

Abstract: A sensor system includes a sensing element, an illumination optical system including a light source, the illumination optical system being configured to obliquely illuminate the sensing element, and a detector device configured to detect light reflected off the sensing element. The sensing element includes a chemical sensing layer configured to change in an optical characteristic in response to contact with a target substance, a reflection layer configured to reflect at least part of incident light, and an intermediate layer located between the reflection layer and the chemical sensing layer. The detector device is configured to separately detect p-polarized light and s-polarized light reflected off the sensing element.

Abstract: An optical detection type chemical sensor includes a light source, a detection element and a photodetector. The detection element is constituted of a laminate in which a multilayer film including a chemical detection layer, an optical interference layer, and a half mirror layer is formed on a transparent substrate. At least one of the layers includes a magnetic material. Light from the light source is applied to the detection element under the condition that the light enters inside of the detection element from the rear surface of the transparent substrate on which the laminate is not formed and multiple reflection occurring in the laminate intensifies the magneto-optical effect. A subject is detected by using the photodetector to detect a magneto-optical signal indicating a change in reflected light from the laminate resulting from a change in an optical property resulting from a reaction in the chemical detection layer.

Abstract: A fluorescent image analyzer stores a reference fluorescent-sample image and a subject fluorescent-sample image. The reference fluorescent-sample image is an image obtained by illuminating a reference fluorescent sample about which relation of in-plane fluorescence intensities is known with linearly polarized light and capturing a first specific polarization component of fluorescence from the reference fluorescent sample. The subject fluorescent-sample image is an image obtained by illuminating a subject fluorescent sample with linearly polarized light and capturing a second specific polarization component of fluorescence from the subject fluorescent sample. The fluorescent image analyzer is configured to determine correction coefficients to correct non-uniformity in measurement of light intensities among pixels of a captured image based on the reference fluorescent-sample image, and correct light intensities of the pixels of the subject fluorescent-sample image based on the correction coefficients.

Abstract: A light ray direction control element includes a first light transmitting substrate, a second light transmitting substrate facing the first light transmitting substrate, a first light transmitting region provided on a first main surface of the first light transmitting substrate, a second light transmitting region provided on a first main surface of the second light transmitting substrate, first light absorbing regions positioned among the first light transmitting region, and second light absorbing regions positioned among the second light transmitting region. The light ray direction control element further includes a light transmitting dispersion medium enclosed in the first light absorbing regions and the second light absorbing regions, and charged electrophoretic particles dispersed in the light transmitting dispersion medium.

Abstract: Provided is a support for fluorescence polarization immunoassay of which reaction parts are loaded with an antibody and a fluorescent labeling substance. The plurality of reaction parts may be loaded with different concentrations of an antibody and a fluorescent labeling substance. Further, antibodies having different binding affinities for a target substance may be loaded. With such a support, fluorescence polarizations can be measured simply by adding a sample solution containing a target substance to the reaction parts, and a wide measurement range of the concentration the target substance can be secured.

Abstract: A microdevice includes a plurality of calibration curve liquids, a plurality of first microchannels respectively filled with the plurality of calibration curve liquids, at least one second microchannel filled with a measurement target liquid, and a sealing member that closes openings of the first microchannels to seal the calibration curve liquids. Each of the calibration curve liquids includes a measurement target substance of a predetermined concentration, the predetermined concentration in each of the plurality of calibration curve liquid being mutually different, an antibody that specifically binds to the measurement target substance, and a fluorescent-labeling derivative that fluorescently labels the measurement target substance and competes with the measurement target substance to specifically bind to the antibody. The measurement target liquid includes an unknown concentration of the measurement target substance, the antibody, and the fluorescent-labeling derivative.

Abstract: A light distribution control device includes: first upper electrodes and second upper electrodes disposed alternately in a first direction; first lower electrodes and second lower electrodes disposed alternately in a second direction that crosses the first direction; light transmissive regions disposed between an upper electrode set consisting of the first upper electrodes and the second upper electrodes and a lower electrode set consisting of the first lower electrodes and second lower electrodes; and colored electrophoretic particles and a dispersion medium contained in a space between light transmissive regions. Each of the first upper electrodes extends along the space between light transmissive regions. Each of the second upper electrodes extends along a line of light transmissive regions. Each of the first lower electrodes extends along the space between light transmissive regions. Each of the second lower electrodes extends along a line of light transmissive regions.

Abstract: A display device includes: a display module including elemental pixel groups, each of the elemental pixel groups being configured to display an elemental image for displaying a reproduced image; an elemental lens array including elemental lenses, the elemental lenses being provided in front of the elemental pixel groups in one-to-one correspondence; a diopter adjustment element array including diopter adjustment elements, the diopter adjustment elements being provided in front of the plurality of elemental lenses in one-to-one correspondence; and a controller. The controller is configured to: control a part of the diopter adjustment elements in accordance with visual acuity of one eye of a user; and control the other part of the diopter adjustment elements in accordance with visual acuity of the other eye of the user.

Abstract: An optical detection type chemical sensor includes a light source, a detection element and a photodetector. The detection element is constituted of a laminate in which a multilayer film including a chemical detection layer, an optical interference layer, and a half mirror layer is formed on a transparent substrate. At least one of the layers includes a magnetic material. Light from the light source is applied to the detection element under the condition that the light enters inside of the detection element from the rear surface of the transparent substrate on which the laminate is not formed and multiple reflection occurring in the laminate intensifies the magneto-optical effect. A subject is detected by using the photodetector to detect a magneto-optical signal indicating a change in reflected light from the laminate resulting from a change in an optical property resulting from a reaction in the chemical detection layer.

Abstract: A microdevice includes: a microchannel to which a measurement target solution containing a measurement target substance is introduced; an antibody being fixed to at least one sidewall surface of the microchannel and specifically binding to the measurement target substance; a fluorescence-labeled derivative being specifically bound to the antibody and being acquired by fluorescence-labeling the measurement target substance; and a light blocker blocking excitation light exciting fluorescent light radiated by the fluorescence-labeled derivative. The measurement target substance and the fluorescence-labeled derivative specifically bind to the antibody in a competitive manner, and the antibody is fixed to the sidewall surface of the microchannel in a state of specifically binding to the fluorescence-labeled derivative. The light blocker blocks the excitation light entering the fluorescence-labeled derivative specifically binding to the antibody.

Abstract: A display device includes: a display module including elemental pixel groups, each of the elemental pixel groups being configured to display an elemental image for displaying a reproduced image; an elemental lens array including elemental lenses, the elemental lenses being provided in front of the elemental pixel groups in one-to-one correspondence; a diopter adjustment element array including diopter adjustment elements, the diopter adjustment elements being provided in front of the plurality of elemental lenses in one-to-one correspondence; and a controller. The controller is configured to: control a part of the diopter adjustment elements in accordance with visual acuity of one eye of a user; and control the other part of the diopter adjustment elements in accordance with visual acuity of the other eye of the user.

Abstract: A sample solution preparation method, a measurement cell, a measurement kit, and a sample solution preparation device for measuring a target compound contained in food by an immunity analysis method using fluorescence. The present disclosure features including a dialysis step for bringing a target compound-containing solution that includes the target compound into contact with a dialysis fluid through a dialysis membrane to transfer the target compound to the dialysis fluid, in which the molecular weight cut-off of the dialysis membrane is within a range of 2×102 to 2×105, and the volume of the dialysis fluid is relatively smaller than the volume of the target compound-containing solution.