Patents by Inventor Ken-Tye Yong

Ken-Tye Yong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of using gold nanorods-siRNA complexes
    Patent number: 8035016
    Abstract: Provided are methods and compositions for inhibiting expression of one or more target genes. The compositions contain RNA polynucleotides that can inhibit expression of a target gene via RNA interference (RNAi) electrostatically complexed with surface functionalized gold nanorods (GNRs). The RNA polynucleotides are not covalently bound to the surface functionalized GNRs. The method involves inhibiting expression of a target gene in an individual. The method is performed by administering to the individual an effective amount of a composition containing surface functionalized GNRs electrostatically complexed with RNA polynucleotides, such as siRNA, that can inhibit expression of the target gene via RNAi. The siRNA is not covalently bound to the surface functionalized GNRs.
    Type: Grant
    Filed: September 8, 2009
    Date of Patent: October 11, 2011
    Assignee: The Research Foundation of State University of New York
    Inventors: Earl J. Bergey, Adela Bonoiu, Supriya Mahajan, Paras N. Prasad, Indrajit Roy, Stanley A. Schwartz, Ken-Tye Yong
  • GOLD NANOROD-siRNA COMPLEXES AND METHODS OF USING SAME
    Publication number: 20100125100
    Abstract: Provided are methods and compositions for inhibiting expression of one or more target genes. The compositions contain RNA polynucleotides that can inhibit expression of a target gene via RNA interference (RNAi) electrostatically complexed with surface functionalized gold nanorods (GNRs). The RNA polynucleotides are not covalently bound to the surface functionalized GNRs. The method involves inhibiting expression of a target gene in an individual. The method is performed by administering to the individual an effective amount of a composition containing surface functionalized GNRs electrostatically complexed with RNA polynucleotides, such as siRNA, that can inhibit expression of the target gene via RNAi. The siRNA is not covalently bound to the surface functionalized GNRs.
    Type: Application
    Filed: September 8, 2009
    Publication date: May 20, 2010
    Inventors: Earl J. Bergey, Adela Bonoiu, Supriya Mahajan, Paras N. Prasad, Indrajit Roy, Stanley A. Schwartz, Ken-Tye Yong
  • NON-SPHERICAL SEMICONDUCTOR NANOCRYSTALS AND METHODS OF MAKING THEM
    Publication number: 20070186846
    Abstract: The present invention relates to a method of making non-spherical semiconductor nanocrystals. This method involves providing a reaction mixture containing a first precursor compound, a solvent, and a surfactant, where the first precursor compound has a Group II or a Group IV element and contacting the reaction mixture with a pure noble metal nanoparticle seed. The reaction mixture is heated. A second precursor compound having a Group VI element is added to the heated reaction mixture under conditions effective to produce non-spherical semiconductor nanocrystals. Non-spherical semiconductor nanocrystals and nanocrystal populations made by the above method are also disclosed.
    Type: Application
    Filed: December 21, 2006
    Publication date: August 16, 2007
    Applicant: The Research Foundation of State University of New York
    Inventors: Ken-Tye Yong, Yudhisthira Sahoo, Mark Swihart, Paras Prasad