Patents by Inventor Ken Valenzano

Ken Valenzano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapy Regimens, Dosing Regimens And Stable Medicaments For The Treatment Of Pompe Disease
    Publication number: 20110268721
    Abstract: The present application provides a method for treating Pompe disease in a subject in need thereof, that includes a method of administering to the subject a GAA enzyme in combination with an ASSC for the GAA enzyme. The present application also provides methods for increasing the in vitro and in vivo stability of a GAA enzyme formulation.
    Type: Application
    Filed: May 11, 2011
    Publication date: November 3, 2011
    Applicant: Amicus Therapeutics, Inc.
    Inventors: Hung V. Do, Ken Valenzano, David J. Lockhart
  • THERAPY REGIMENS, DOSING REGIMENS AND STABLE MEDICAMENTS FOR THE TREATMENT OF POMPE DISEASE
    Publication number: 20100119502
    Abstract: The present application provides a method for treating Pompe disease in a subject in need thereof, that includes a method of administering to the subject a GAA enzyme in combination with an ASSC for the GAA enzyme. The present application also provides methods for increasing the in vitro and in vivo stability of a GAA enzyme formulation.
    Type: Application
    Filed: November 11, 2009
    Publication date: May 13, 2010
    Applicant: AMICUS THERAPEUTICS, INC.
    Inventors: Hung V. Do, Ken Valenzano, David J. Lockhart
  • PHARMACOLOGICAL CHAPERONES FOR TREATING OBESITY
    Publication number: 20090312345
    Abstract: The invention relates to methods of enhancing normal melanocortin-4 receptor (MC4R) activity, and to enhancing activity of an MC4R having a mutation which affects protein folding and/or processing of the MC4R. The invention provides a method of treating an individual having a condition in which increased activity of an MC4R at the cell surface would be beneficial, for example in obesity, by administering an effective amount of a pharmacological chaperone for the MC4R. The invention provides MC4R pharmacological chaperones which enhance the activity of MC4R. The invention further provides a method of screening to identify pharmacological chaperones which enhance folding of an MC4R in the endoplasmic reticulum (ER), in order to enhance the activity of the MC4R at the cell surface.
    Type: Application
    Filed: August 3, 2009
    Publication date: December 17, 2009
    Applicants: AMICUS THERAPEUTICS, INC., UNIVERSITE DE MONTREAL
    Inventors: Jian-Qiang Fan, Ken Valenzano, Gary Lee, Michel Bouvier
  • Pharmacological chaperones for treating obesity
    Publication number: 20070021433
    Abstract: The invention relates to methods of enhancing normal melanocortin-4 receptor (MC4R) activity, and to enhancing activity of an MC4R having a mutation which affects protein folding and/or processing of the MC4R. The invention provides a method of treating an individual having a condition in which increased activity of an MC4R at the cell surface would be beneficial, for example in obesity, by administering an effective amount of a pharmacological chaperone for the MC4R. The invention provides MC4R pharmacological chaperones which enhance the activity of MC4R. The invention further provides a method of screening to identify pharmacological chaperones which enhance folding of an MC4R in the endoplasmic reticulum (ER), in order to enhance the activity of the MC4R at the cell surface.
    Type: Application
    Filed: June 2, 2006
    Publication date: January 25, 2007
    Inventors: Jian-Qiang Fan, Ken Valenzano, Gary Lee, Michel Bouvier