Abstract: The invention relates to compounds, methods and compositions for improving on nucleic acid polymerization, including DNA replication by in vitro primer extension to generate, for example, polymers for nanopore-based single molecule sequencing of a DNA template. A nucleic acid polymerase reaction composition is provided with polymerization enhancement moieties, which allows enhanced DNA polymerase activity with nucleotide analogs, resulting in improved length of primer extension products for sequencing applications.

Abstract: A method for facilitating the design and manufacturing of a tiltrotor aircraft, including the steps of: determining a compatible mission data set; identifying lift propulsion module components for the compatible mission data set; determining compatible specifications; and generating a design for a lift propulsion module; wherein the lift propulsion module is configured to be connected to at least two different fuselages. There is also a method of designing a tiltrotor aircraft, comprising the step of modularizing a lift propulsion system, wherein the lift propulsion system is configured to be connected to at least two different fuselages. In another aspect, there is a tiltrotor aircraft including a fuselage; and a lift propulsion module, the lift propulsion module including a mounting surface; wherein the lift propulsion module is coupled to the fuselage on the mounting surface. Also included are methods of assembling and systems including a lift propulsion module.

Abstract: A method for facilitating the design and manufacturing of a tiltrotor aircraft, including the steps of: determining a compatible mission data set; identifying lift propulsion module components for the compatible mission data set; determining compatible specifications; and generating a design for a lift propulsion module; wherein the lift propulsion module is configured to be connected to at least two different fuselages. There is also a method of designing a tiltrotor aircraft, comprising the step of modularizing a lift propulsion system, wherein the lift propulsion system is configured to be connected to at least two different fuselages. In another aspect, there is a tiltrotor aircraft including a fuselage; and a lift propulsion module, the lift propulsion module including a mounting surface; wherein the lift propulsion module is coupled to the fuselage on the mounting surface. Also included are methods of assembling and systems including a lift propulsion module.