Patents by Inventor Kendall Mark Mohler

Kendall Mark Mohler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TNF-a ANTAGONIST MULTI-TARGET BINDING PROTEINS
    Publication number: 20110152173
    Abstract: This disclosure provides a multi-target fusion protein composed of a TNF-? antagonist domain and another binding domain antagonistic for a heterologous target, such as IL6, RANKL, IL7, IL17A/F, TWEAK, CSF2, IGF1, IGF2 or BLyS/APRIL, or agonistic for a heterologous target, such as IL10. The multi-specific fusion protein may also include an intervening domain that separates the binding domains and allows for dimerization. This disclosure also provides polynucleotides encoding the multi-specific fusion proteins, compositions of the fusion proteins, and methods of using the multi-specific fusion proteins and compositions.
    Type: Application
    Filed: July 2, 2009
    Publication date: June 23, 2011
    Inventors: Alan Keith Lofquist, Kendall Mark Mohler, Peter Robert Baum, Peter Armstrong Thompson, Lynda Misher