Patents by Inventor Keng Boon Dave WEE

Keng Boon Dave WEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating cancer by antisense oligonucleotides targeting PRDM15
    Patent number: 11136579
    Abstract: The present invention relates to antisense oligonucleotides for modulating the activity of PRDM15 and use thereof in the treatment of cancer. In particular, said antisense oligonucleotides are capable of inducing the skipping of an exon of a PRDM15 mRNA. The present invention also relates to a method for determining prognosis in a patient with cancer, or selecting a therapeutic strategy for a patient with cancer, by assessing the level of PRDM15 nucleic acid, protein or activity in a sample.
    Type: Grant
    Filed: September 4, 2017
    Date of Patent: October 5, 2021
    Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Ernesto Guccione, Keng Boon Dave Wee
  • METHOD OF TREATING CANCER BY ANTISENSE OLIGONUCLEOTIDES TARGETING PRDM15
    Publication number: 20200181612
    Abstract: The present invention relates to antisense oligonucleotides for modulating the activity of PRDM15 and use thereof in the treatment of cancer. In particular, said antisense oligonucleotides are capable of inducing the skipping of an exon of a PRDM15 mRNA. The present invention also relates to a method for determining prognosis in a patient with cancer, or selecting a therapeutic strategy for a patient with cancer, by assessing the level of PRDM15 nucleic acid, protein or activity in a sample.
    Type: Application
    Filed: September 4, 2017
    Publication date: June 11, 2020
    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Ernesto GUCCIONE, Keng Boon Dave WEE