Abstract: A field flow fractionator (FFF device) 1 classifies particles in a liquid sample by applying a field to a liquid sample supplied from a sample injection device 5. A detector 6 detects the particles in the liquid sample classified by the FFF device 1. A bypass flow path 8 supplies the liquid sample from the sample injection device 5 to the detector 6 without via the FFF device 1. A rotary valve (flow path switching unit) 4 switches a flow path to guide the liquid sample from the sample injection device 5 to the FFF device 1 or a bypass flow path 8. The bypass flow path 8 is provided with a concentration adjusting device 9 for adjusting the concentration of the liquid sample from the sample injection device 5. In a case where a sample with the same quantity as the sample supplied to the FFF device 1 is supplied to the bypass flow path 8 at the time of analysis, the sample is diluted by the concentration adjusting device 9 such that a detection signal from the detector 6 falls within a dynamic range.

Abstract: Labels (2a, 2b) of the first label group and labels (2c, 2d) of the second label group are different from each other in label property. In each particle group, a plurality of particle subgroups (a to d) are different from each other in particle size. A measurement method further comprises: mixing a specimen, particles (1a to 1d), and labels (2a to 2d); allowing biomolecules to specifically bind to the labels (2a to 2d) and to the labels (2a to 2d); separating the particles based on particle sizes; detecting label properties of the labels; determining types of the biomolecules bound to the particles based on the particle size and the label property.

Abstract: A centrifugal field-flow fractionation device includes: a rotor having a rotation axis, the rotor being provided to be rotatable about the rotation axis; a cover covering the rotor; a protective member arranged inside the cover to over the rotor about the rotation axis; a shock-absorbing member arranged between the protective member and the cover; and a fixing part provided in a breakable manner to fix the protective member to the cover. The rotor is arranged such that the rotation axis orients in a horizontal direction. In a case where a part of the rotor disintegrates and is brought into contact with the protective member during the rotation of the rotor, the fixing part breaks to cause the protective member and the shock-absorbing member to move with the rotor while receiving the impact of the rotor to buffer the kinetic energy of the rotor.

Abstract: A centrifugal field-flow fractionation device is provided with a controller for controlling introduction of a liquid sample by a sample introduction part and rotation of the rotor by a motor. The controller rotates the rotor at a first rotational speed when introducing the liquid sample into a flow path. The first rotational speed is faster than a second rotational speed. Therefore, when a liquid sample is introduced into the flow path, high centrifugal force can be applied to the liquid sample, which can suppress the variation of the particles in the liquid sample introduced to the flow path. The controller rotates the rotor at the second rotational speed slower than the first rotational speed with the liquid sample flow in the flow path stopped. Therefore, it is possible to prevent the constant application of high centrifugal force to the liquid sample, thereby suppressing the increase in the length of time required for analysis.

Abstract: The present disclosure provides a method of detecting size, density, or size and density of the lipid nanoparticles. The detection may be performed by centrifugal field flow fractionation using a carrier solution comprising a monosaccharide.

Abstract: An information processing device is connected through a network to a plurality of clients configured to participate in virtual spaces, and is capable of synchronizing a synchronization target object in the virtual spaces among clients of the plurality of clients in a synchronization group. The synchronization target object includes terrain information for reproducing contents constituting the virtual spaces.

Abstract: An information processing device is connected through a network to a plurality of clients configured to participate in virtual spaces, and is capable of synchronizing a synchronization target object in the virtual spaces among clients of the plurality of clients in a synchronization group. The synchronization target object includes terrain information for reproducing contents constituting the virtual spaces.

Abstract: A server device is connected through a network to a plurality of clients configured to participate in a virtual space, a synchronization target object in the virtual space being synchronized between clients of a synchronization group including a client that has ownership of the object and a client that does not have ownership of the object, and the server device includes: data reception means configured to receive a difference of the synchronization target object from the client that has ownership of the object; data update means configured to update replicas obtained by replicating the synchronization target object by using the difference; and data transmission means configured to transmit the difference to a client other than the client that has ownership among the plurality of clients.

Abstract: A temperature adjustment circuit includes a first temperature adjustment circuit and a second temperature adjustment circuit in which a switching part that is configured to switch between a circulation state where a heat-transfer medium is circulated through a connection circuit in which the first temperature adjustment circuit and the second temperature adjustment circuit are connected to each other and a non-circulation state where the heat-transfer medium is not circulated through the connection circuit.

Abstract: A server device is connected through a network to a plurality of clients configured to participate in a virtual space, a synchronization target object in the virtual space being synchronized between clients of a synchronization group including a client that has ownership of the object and a client that does not have ownership of the object, and the server device includes: data reception means configured to receive a difference of the synchronization target object from the client that has ownership of the object; data update means configured to update replicas obtained by replicating the synchronization target object by using the difference; and data transmission means configured to transmit the difference to a client other than the client that has ownership among the plurality of clients.

Abstract: A centrifugal separation type FFF device where a rotor can be rotated at a high speed safely so that particles of a smaller size in a sample liquid can be classified. A field flow fractionation device is provided with: a channel that is attached to the inner circumferential surface of the peripheral portion of a rotor and where a classification flow path is created; flow paths for feeding a sample liquid into and out from the classification flow path; and a rotational drive mechanism for rotating the rotational axis, wherein a channel installation portion is formed on one side of the peripheral portion, and a mass balancer portion for adjusting the mass distribution of the rotor is formed on the other side with the rotor base in between.

Abstract: A temperature adjustment circuit includes a first temperature adjustment circuit and a second temperature adjustment circuit in which a control device is configured to switch between a circulation state where a heat-transfer medium is circulated through a connection circuit in which the first temperature adjustment circuit and the second temperature adjustment circuit are connected to each other and a non-circulation state where the heat-transfer medium is not circulated through the connection circuit.

Abstract: A vehicle includes a battery, an air conditioner, a first temperature adjustment circuit including a first pump and a chiller, a second temperature adjustment circuit including a second pump and a radiator, a coupling passage configured to connect the first temperature adjustment circuit and the second temperature adjustment circuit to form a coupling circuit, an electromagnetic switching valve configured to switch between a circulation state in which the heat medium can circulate through the coupling circuit and a non-circulation state in which the heat medium cannot circulate through the coupling circuit, a first temperature sensor configured to acquire a first temperature which is a temperature of the battery, and a control device configured to select any one mode of a plurality of modes in accordance with the first temperature.

Abstract: Provided is a centrifugal field-flow fractionation device capable of suppressing deformation of a channel member. Pressure in a channel formed inside the channel member in a centrifugal field-flow fractionation device 1 is increased by a pressure increasing mechanism 8 provided downstream of the centrifugal field-flow fractionation device 1. In this manner, an inner surface of the channel is pressed outward by a liquid sample in the channel, and an outer peripheral surface and an inner peripheral surface of the channel member can be suppressed from being recessed toward the channel side.

Abstract: A centrifugal field-flow fractionation device is provided with a controller for controlling introduction of a liquid sample by a sample introduction part and rotation of the rotor by a motor. The controller rotates the rotor at a first rotational speed when introducing the liquid sample into a flow path. The first rotational speed is faster than a second rotational speed. Therefore, when a liquid sample is introduced into the flow path, high centrifugal force can be applied to the liquid sample, which can suppress the variation of the particles in the liquid sample introduced to the flow path. The controller rotates the rotor at the second rotational speed slower than the first rotational speed with the liquid sample flow in the flow path stopped. Therefore, it is possible to prevent the constant application of high centrifugal force to the liquid sample, thereby suppressing the increase in the length of time required for analysis.

Abstract: A centrifugal field-flow fractionation device includes: a rotor having a rotation axis, the rotor being provided to be rotatable about the rotation axis; a cover covering the rotor; a protective member arranged inside the cover to over the rotor about the rotation axis; a shock-absorbing member arranged between the protective member and the cover; and a fixing part provided in a breakable manner to fix the protective member to the cover. The rotor is arranged such that the rotation axis orients in a horizontal direction. In a case where a part of the rotor disintegrates and is brought into contact with the protective member during the rotation of the rotor, the fixing part breaks to cause the protective member and the shock-absorbing member to move with the rotor while receiving the impact of the rotor to buffer the kinetic energy of the rotor.

Abstract: A field flow fractionator (FFF device) 1 classifies particles in a liquid sample by applying a field to a liquid sample supplied from a sample injection device 5. A detector 6 detects the particles in the liquid sample classified by the FFF device 1. A bypass flow path 8 supplies the liquid sample from the sample injection device 5 to the detector 6 without via the FFF device 1. A rotary valve (flow path switching unit) 4 switches a flow path to guide the liquid sample from the sample injection device 5 to the FFF device 1 or a bypass flow path 8. The bypass flow path 8 is provided with a concentration adjusting device 9 for adjusting the concentration of the liquid sample from the sample injection device 5. In a case where a sample with the same quantity as the sample supplied to the FFF device 1 is supplied to the bypass flow path 8 at the time of analysis, the sample is diluted by the concentration adjusting device 9 such that a detection signal from the detector 6 falls within a dynamic range.

Abstract: Obtaining sufficient suppression effect of channel diffusion and stably transferring solution are made possible even in a piping having an extremely small inner diameter used for an analysis apparatus such as an HPLC. A piping device for an analysis apparatus includes a piping equipped with a folded shape that suppresses inner channel diffusion, and a member directly or indirectly in contact with the piping from at least one side to support the piping to suppress deformation of the folded shape.

Abstract: A centrifugal field-flow fractionation device includes an annular rotor, an arc-shaped channel member, a rotation drive unit, and a restriction unit. A channel member 16 is provided along an inner peripheral surface of the rotor, has therein a channel 161 for a liquid sample by laminating a plurality of layers, and has an inlet for the liquid sample to the channel 161 and an outlet for the liquid sample from the channel 161. By rotating the rotor, particles in the liquid sample in the channel 161 are classified by centrifugal force. A restriction spacer 64 restricts the channel 161 from being compressed to a height less than a certain height when the channel member 16 is compressed and deformed in a laminating direction.