Patents by Inventor Kenian YAN

Kenian YAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOINDOLINE COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF
    Publication number: 20220041576
    Abstract: The present invention relates to a polysubstituted isoindoline compound as shown in general formula (I), and a preparation method, a pharmaceutical composition and the use thereof. In particular, the polysubstituted isoindoline compound is provided in the present invention as a class of novel CRL4CRBN E3 ubiquitin ligase modulators in structure, wherein same has a stronger antitumor activity and antitumor spectrum, and can be used to prepare drugs for treating CRL4CRBN E3 ligase-related diseases.
    Type: Application
    Filed: September 30, 2019
    Publication date: February 10, 2022
    Inventors: Xiaohua CHEN, Jia LI, Yu CHENG, Yubo ZHOU, Huijun NIE, Yujie WANG, Hongtao TIAN, Weijuan KAN, Tian MI, Xiaobei HU, Binshan ZHOU, Kenian YAN, Gaoya XU, Yuhua ZHONG, Lei FENG