Patents by Inventor Kenichi Hashiguchi

Kenichi Hashiguchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for producing L-valine and L-leucine
    Patent number: 5888783
    Abstract: L-valine is produced by culturing a microorganism belonging to the genus Escherichia with the capability of producing L-valine or L-leucine wherein it requires lipoic acid for growth, a microorganism belonging to the genus Escherichia with the capability of producing L-valine or L-leucine wherein it is deficient in H.sup.+ -ATPase activity, a microorganism belonging to the genus Escherichia with the capability of producing L-valine or L-leucine wherein it requires lipoic acid for growth and is deficient in H.sup.+ -ATPase activity, in the liquid medium to allow the L-valine to be produced and accumulated in a culture medium, and collecting it.
    Type: Grant
    Filed: February 28, 1997
    Date of Patent: March 30, 1999
    Assignee: Ajinomoto Co., Inc.
    Inventors: Fusao Tomita, Atsushi Yokota, Kenichi Hashiguchi, Masako Ishigooka, Osamu Kurahashi
  • Bacillus-derived transglutaminase
    Patent number: 5731183
    Abstract: The present invention relates to (1) a transglutaminase (hereinafter referred to as TG) isolated from a Bacilli such as those of Bacillus subtilis, (2) a fraction having transglutaminase activity, and (3) a method for producing a protein, a non-proteinaceous amino acid polymer, a peptide or derivatives thereof having a crosslinked structure, by crosslinking the glutamine and lysine residues in the same with the TG or the fraction having TG activity to thereby form intermolecular or intramolecular, crosslinked .epsilon.-(.gamma.-Glu)-Lys bonds. The present invention also relates to (4) a DNA coding for a TG derived from a Bacilli such as Bacillus subtilis, (5) a vector comprising said DNA coding for the TG, (6) a cell transformed with the vector, and (7) a method for producing a Bacillus-derived transglutaminase by incubating the transformant.
    Type: Grant
    Filed: February 9, 1996
    Date of Patent: March 24, 1998
    Assignee: Ajinomoto Co., Inc.
    Inventors: Katsunori Kobayashi, Shigeru Yamanaka, Kiyoshi Miwa, Shunichi Suzuki, Yuzuru Eto, Yuko Tanita, Kenzo Yokozeki, Kenichi Hashiguchi