Abstract: A cell accommodating chip is adapted for use in a screening apparatus for searching for a predetermined cell based on optical information emitted from a substance on the cell accommodating chip and selectively collecting the cell searched for. The cell accommodating chip includes a substrate composed of a light-transmitting material, and a plurality of wells capable of accommodating cells, the plurality of wells being provided on at least one of main faces of the substrate. A surface of the cell accommodating chip having the plurality of wells is coated with a specific polymer having a crosslinked structure.

Abstract: The disclosed technology is directed to a treatment system comprises a power supply apparatus and a treatment instrument configured to communicate electrically with the power supply apparatus so as to perform a treatment on a biological tissue. The treatment instrument includes an end effector that transmits a high-frequency current delivered by a first electrical energy to the biological tissue. An electric element is configured to operate the end effector by being actuated using second electric energy. The power supply apparatus includes a processor configured to receive a stop command to cutoff the supply of the first electric energy and the second electric energy in a state in which the first electric energy and the second electric energy are supplied and determine whether or not the end effector is in contact with the biological tissue based on a parameter related to the first electric energy after receiving the stop command.

Abstract: A cell accommodating chip capable of accommodating a plurality of cells includes a substrate composed of a light-transmitting material, and a plurality of wells on at least one of main faces of the substrate, the plurality of wells being capable of accommodating cells. A surface of the cell accommodating chip including the plurality of wells has a low cell adhesion property, and affinity to a specific binding material having affinity to a produced substance produced by a cell accommodated in one of the wells and/or a released substance released by the cell.

Abstract: An analyte identifying and sorting apparatus for sorting a target analyte based on an identification result of analytes dispersed in a liquid. The apparatus includes an identification unit including an analyte storage section configured to store analytes dispersed in a liquid, a pressure control section configured to feed the liquid to a flow path provided to extend downward from the analyte storage section, a light irradiation section configured to irradiate light to the analytes, an optical information measurement section measuring optical information of the analytes, and a determination section determining whether the analyte is a target analyte or a non-target analyte based on the optical information.

Abstract: The invention provides a composite capable of achieving both excellent followability to an adherend and excellent adhesion. The composite has a support and a plurality of structures fixed to at least one surface of the support, and the structure has a shaft member consisting of a flexible material extending from a proximal end fixed to the support, and an adhesive part arranged at a distal end of the shaft member.

Abstract: A treatment device includes a vibrator capable of ultrasonically vibrating, a front mass portion having a first resonance frequency and connected to the vibrator in a manner capable of transmitting ultrasonic vibration, a treatment probe configured to treat a subject and having a second resonance frequency that is higher than the first resonance frequency of the front mass portion, and a connection portion connecting a distal end surface of the front mass portion and a proximal end surface of the treatment probe by a pressing force, and serving as an antinode position when vibrating at the first resonance frequency.

Abstract: A generator that includes a drive circuit connected to a surgical instrument including a vibration system having a probe and an ultrasonic transducer, which supplies power to the ultrasonic transducer. The control circuit detects a first trigger causing the control circuit to perform a resonance-point search on the vibration system. Upon detecting the first trigger, the control circuit determines a resonance point of a frequency of vibration of the probe by performing the resonance-point search, and upon determining the resonance point, causes the drive circuit to execute a standby operation. The control circuit then detects a second trigger causing the surgical instrument to treat the living tissue, and upon detecting the second trigger, causes the drive circuit to execute an actual output operation by increasing the supply of power to the surgical instrument such that the surgical instrument treats the living tissue.

Abstract: The disclosed technology is directed to a treatment system comprises a power supply apparatus and a treatment instrument configured to communicate electrically with the power supply apparatus so as to perform a treatment on a biological tissue. The treatment instrument includes an end effector that transmits a high-frequency current delivered by a first electrical energy to the biological tissue. An electric element is configured to operate the end effector by being actuated using second electric energy. The power supply apparatus includes a processor configured to receive a stop command to cutoff the supply of the first electric energy and the second electric energy in a state in which the first electric energy and the second electric energy are supplied and determine whether or not the end effector is in contact with the biological tissue based on a parameter related to the first electric energy after receiving the stop command.

Abstract: A screening apparatus for searching for a predetermined microparticle based on optical information emitted from microparticles to selectively pick up the microparticle searched for includes a measurement chip that is made of a light permeable material, the measurement chip having a well formed therein that retains a liquid including at least one microparticle, a measuring section that is configured to acquire optical information emitted by the microparticles retained in the measurement chip, an analyzing section that is configured to analyze the optical information to extract optical information associated with the microparticles retained in the well, a liquid retaining section provided on the measurement chip, a draining section that is configured to drain a liquid retained in the liquid retaining section, an introducing section that introduces a liquid into the liquid retained section, and a liquid level controlling section that controls a liquid level of the liquid retaining section.

Abstract: A surgical treatment apparatus includes a treatment portion unit; at least one operation portion provided in the treatment portion unit that is movable in response to an operation of an operator; a detection subject portion provided in the operation portion; a gripping portion that is detachable and attachable relative to the treatment portion unit; a non-contact type detection portion that is provided in the gripping portion separately from the operation portion and is capable of detecting an operation of the detection subject portion in accordance with the operation of the operation portion; an energy supply portion provided within the gripping portion, that supplies energy to the treatment portion; and a driving device connected to the gripping portion, that supplies energy to the energy supply portion in accordance with a detection result of the detection portion.

Abstract: Provided is a liquid feeding device which can improve collection efficiency of fine particles on an individual particle basis while improvement of workability is realized. A liquid feeding device includes: an introduction portion disposed on one end portion of the liquid feeding device, and configured to introduce a liquid into a closed space; a discharge portion disposed on another end portion of the liquid feeding device, and configured to discharge the liquid supplied into the closed space; and an upper wall provided so as to oppose the upper surface of the chip, and configured to define the closed space. The upper wall has an inclined surface which is provided such that a gap formed between the inclined surface and the chip is reduced from an introduction portion side toward a discharge portion side.

Abstract: A cell accommodating chip capable of accommodating a plurality of cells includes a substrate composed of a light-transmitting material, and a plurality of wells on at least one of main faces of the substrate, the plurality of wells being capable of accommodating cells. A surface of the cell accommodating chip including the plurality of wells has a low cell adhesion property, and affinity to a specific binding material having affinity to a produced substance produced by a cell accommodated in one of the wells and/or a released substance released by the cell.

Abstract: A cell accommodating chip is adapted for use in a screening apparatus for searching for a predetermined cell based on optical information emitted from a substance on the cell accommodating chip and selectively collecting the cell searched for. The cell accommodating chip includes a substrate composed of a light-transmitting material, and a plurality of wells capable of accommodating cells, the plurality of wells being provided on at least one of main faces of the substrate. A surface of the cell accommodating chip having the plurality of wells is coated with a specific polymer having a crosslinked structure.

Abstract: It is an object of the present invention to provide an excellent method for producing an excellent therapeutic agent. The solution of the present invention is as shown in the following scheme: wherein R1 represents a C1-C6 alkyl group, R2 represents a C1-C6 alkyl group, and R3 represents a C1-C6 alkyl group.

Abstract: A treatment system includes a pair of holding members, a high-frequency energy output section, a heat generating section and a control section. At least one of the pair of holding members moves to the other holding member. The high-frequency energy output section and the heat generating section are provided on at least one of the holding members. The high-frequency energy output section exerts high-frequency energy to a living tissue to denature the living tissue, and collects the biological information of the living tissue. The heat generating section applies heat to it held between the holding members, generates the heat owing to the supply of the energy, and conducts the heat therefrom to denature the living tissue. The control section controls the output of the energy to the high-frequency energy output section and the heat generating section based on the biological information collected by the high-frequency energy output section.

Abstract: A treatment system includes a pair of holding members, a high-frequency energy output section, a heat generating section and a control section. At least one of the pair of holding members moves to the other holding member. The high-frequency energy output section and the heat generating section are provided on at least one of the holding members. The high-frequency energy output section exerts high-frequency energy to a living tissue to denature the living tissue, and collects the biological information of the living tissue. The heat generating section applies heat to it held between the holding members, generates the heat owing to the supply of the energy, and conducts the heat therefrom to denature the living tissue. The control section controls the output of the energy to the high-frequency energy output section and the heat generating section based on the biological information collected by the high-frequency energy output section.

Abstract: A screening apparatus includes a light permeable measurement chip having a well retaining a liquid including microparticles, a measuring section acquiring optical information of the microparticles obtained by illuminating the microparticles, an analyzing section that extracts optical information of the microparticles, a receiving plate receiving a microparticle selectively picked up from the measurement chip, a moving section moving the measurement chip and the receiving plate against the measuring section, and a collecting section for collecting a microparticle by sucking with the suction-ejection capillary and ejecting on the receiving plate. A distal-end outer dimension of the capillary is greater than a width of the well. The capillary sucks the target microparticle at a position where the distal end of the capillary and the measurement chip are spaced by a predetermined distance and a central axis of the distal end of the capillary and a central axis of the well are mutually displaced.

Abstract: A treatment instrument includes: a proximal side probe transmits ultrasonic vibration from its proximal end to its distal end; a distal side probe configured to transmit the ultrasonic vibration from its proximal end to a treatment portion at its distal end; and a holding portion which holds a state where the proximal end of the distal side probe is into collision with the distal end of the proximal side probe, and a state where vibration is transmittable from the proximal end of the proximal side probe to the distal end of the distal side probe.

Abstract: A treatment device includes a vibrator capable of ultrasonically vibrating, a front mass portion having a first resonance frequency and connected to the vibrator in a manner capable of transmitting ultrasonic vibration, a treatment probe configured to treat a subject and having a second resonance frequency that is higher than the first resonance frequency of the front mass portion, and a connection portion connecting a distal end surface of the front mass portion and a proximal end surface of the treatment probe by a pressing force, and serving as an antinode position when vibrating at the first resonance frequency.

Abstract: A medical apparatus includes a treatment device configured to be capable of treating a subject by applying energy to the subject, an optical fiber including a light emitting face for emitting light into the subject, the optical fiber being connected to the treatment device, and a shield portion that is disposed in front of the light emitting face of the optical fiber, the shield portion being configured to expose the light emitting face when the treatment device does not perform a treatment operation and to shield the light emitting face when the treatment device performs the treatment operation.