Patents by Inventor Kenichiro Matsushima

Kenichiro Matsushima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240140804
    Abstract: A graphene nanoribbon represented by formula (1): wherein R1 represents a linear alkyl group having 1 to 12 carbon atoms, R3 and R4 are both hydrogen atoms, or R3 and R4 taken together form a group represented by —SiR2aR2b—, wherein R2a and R2b are the same or different, and each represents a hydrogen atom, an optionally branched alkyl group having 1 to 4 carbon atoms, or a phenyl group, and n represents an integer of 1 or more, is a novel GNR obtained by a simpler and industrially advantageous method for GNRs.
    Type: Application
    Filed: January 31, 2022
    Publication date: May 2, 2024
    Applicants: National University Corporation Tokai National Higher Education and Research System, TAOKA CHEMICAL CO., LTD.
    Inventors: Kenichiro ITAMI, Hideto ITO, Kaho MATSUSHIMA, Hidefumi NAKATSUJI, Ryoma UENO, Shunsuke ISHIDA, Sachie OKUDA
  • Patent number: 7842799
    Abstract: To improve the activity of a Koji mold protease in a solid or liquid culture medium in the production of foods (e.g., a seasoning), pharmaceuticals (e.g., a digestive agent), protease for use in a detergent and the like. Disclosed are a recombinant vector having capability of increasing the secretion of the Koji mold protease, a Koji mold which is transformed with the vector and has an increased expression of a gene for a protease or an increase secretion of the same, a method for the production of a protease by using the transformed Koji mold, and the like.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: November 30, 2010
    Assignees: Noda Institute for Scientific Research, Kikkoman Corporation
    Inventors: Osamu Hatamoto, Genryou Umitsüki, Masayuki Machida, Motoaki Sano, Akimitsu Tanaka, Chitoshi Oka, Hiroshi Maeda, Hitoshi Tainaka, Touru Ito, Tomomi Uchikawa, Tsutomu Masuda, Kenichiro Matsushima
  • Publication number: 20090130711
    Abstract: To improve the activity of a Koji mold protease in a solid or liquid culture medium in the production of foods (e.g., a seasoning), pharmaceuticals (e.g., a digestive agent), protease for use in a detergent and the like. Disclosed are a recombinant vector having capability of increasing the secretion of the Koji mold protease, a Koji mold which is transformed with the vector and has an increased expression of a gene for a protease or an increase secretion of the same, a method for the production of a protease by using the transformed Koji mold, and the like.
    Type: Application
    Filed: September 19, 2006
    Publication date: May 21, 2009
    Inventors: Osamu Hatamoto, Genryou Umitsuki, Masayuki Machida, Motoaki Sano, Akimitsu Tanaka, Chitoshi Oka, Hiroshi Maeda, Hitoshi Tainaka, Touru Ito, Tomomi Uchikawa, Tsutomu Masuda, Kenichiro Matsushima
  • Patent number: 7186540
    Abstract: A completely novel glutaminase is provided: (a) a protein consisting of an amino acid sequence represented by SEQ ID NO: 2, or (b) a protein consisting of an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 2 by deletion, substitution or addition of one or more amino acids, and possessing glutaminase activity. This protein is a novel glutaminase possessing excellent thermostability and the like.
    Type: Grant
    Filed: December 24, 2002
    Date of Patent: March 6, 2007
    Assignees: National Institute of Advanced Indusrtial Science and Technology, National Institute of Technology and Evaluation, National Research Institute of Brewing
    Inventors: Masayuki Machida, Keietsu Abe, Katsuya Gomi, Kiyoshi Asai, Motoaki Sano, Taishin Kin, Hideki Nagasaki, Akira Hosoyama, Osamu Akita, Naotake Ogasawara, Satoru Kuhara, Kotaro Ito, Kenichiro Matsushima, Yasuji Koyama
  • Patent number: 6951750
    Abstract: Provided are a protein comprising the amino acid sequence as shown in SEQ ID NO: 2 and having prolidase activities, a prolidase gene coding for the protein, a prolidase gene comprising the nucleotide sequence as shown in SEQ ID NO: 1, recombinant DNA having the gene inserted into vector DNA, and a transformant or transductant comprising the recombinant DNA, and a method for producing prolidase using the transformant or transductant. The present invention can improve the prolidase through protein engineering. The present invention can be also used for improving microorganisms used in the production of enzymes for food processing and fermented foods.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: October 4, 2005
    Assignees: Kikkoman Corporation, Noda Institute for Scientific Research
    Inventors: Kotaro Ito, Takeharu Nakahara, Yasuji Koyama, Toshifumi Matsuda, Tadashi Takahashi, Kenichiro Matsushima, Genryou Umitsuki, Tsutomu Masuda
  • Patent number: 6919195
    Abstract: Glutaminase which comprises (a) a protein comprising an amino acid sequence shown in SEQ ID NO: 2, or (b) a protein which comprises an amino acid sequence having deletion, substitution, or addition of one or plurality of amino acids relative to the amino acid sequence (a), and has glutaminase activity. A glutaminase gene which encodes (a) a protein comprising an amino acid sequence shown in SEQ ID NO: 2, or (b) a protein which comprises an amino acid sequence having deletion, substitution, or addition of one or a plurality of amino acids relative to the amino acid sequence (a), and has glutaminase activity. The present invention enables glutaminase to be produced efficiently and thus greatly contributes to the relevant industries.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: July 19, 2005
    Assignee: Kikkoman Corporation
    Inventors: Kenichiro Matsushima, Kotaro Ito, Yasuji Koyama
  • Publication number: 20040082053
    Abstract: A completely novel glutaminase is provided: (a) a protein consisting of an amino acid sequence represented by SEQ ID NO: 2, or (b) a protein consisting of an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 2 by deletion, substitution or addition of one or more amino acids, and possessing glutaminase activity. This protein is a novel glutaminase possessing excellent thermostability and the like.
    Type: Application
    Filed: December 24, 2002
    Publication date: April 29, 2004
    Inventors: Masayuki Machida, Keietsu Abe, Katsuya Gomi, Kiyoshi Asai, Motoaki Sano, Taishin Kin, Hideki Nagasaki, Akira Hosoyama, Osamu Akita, Naotake Ogasawara, Satoru Kuhara, Kotaro Ito, Kenichiro Matsushima, Yasuji Koyama
  • Publication number: 20030186420
    Abstract: Provided are a protein comprising the amino acid sequence as shown in SEQ ID NO: 2 and having prolidase activities, a prolidase gene coding for the protein, a prolidase gene comprising the nucleotide sequence as shown in SEQ ID NO: 1, recombinant DNA having the gene inserted into vector DNA, and a transformant or transductant comprising the recombinant DNA, and a method for producing prolidase using the transformant or transductant.
    Type: Application
    Filed: December 23, 2002
    Publication date: October 2, 2003
    Applicant: Kikkoman Corporation
    Inventors: Kotaro Ito, Takeharu Nakahara, Yasuji Koyama, Toshifumi Matsuda, Tadashi Takahashi, Kenichiro Matsushima, Genryou Umitsuki, Tsutomu Masuda
  • Publication number: 20030040098
    Abstract: Glutaminase which comprises (a) a protein comprising an amino acid sequence shown in SEQ ID NO: 2, or (b) a protein which comprises an amino acid sequence having deletion, substitution, or addition of one or plurality of amino acids relative to the amino acid sequence (a), and has glutaminase activity. A glutaminase gene which encodes (a) a protein comprising an amino acid sequence shown in SEQ ID NO: 2, or (b) a protein which comprises an amino acid sequence having deletion, substitution, or addition of one or a plurality of amino acids relative to the amino acid sequence (a), and has glutaminase activity. The present invention enables glutaminase to be produced efficiently and thus greatly contributes to the relevant industries.
    Type: Application
    Filed: June 20, 2002
    Publication date: February 27, 2003
    Applicant: Kikkoman Corporation
    Inventors: Kenichiro Matsushima, Kotaro Ito, Yasuji Koyama