Patents by Inventor Kenji Chichibu

Kenji Chichibu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of assaying high molecular hyaluronic acid and kit of reagents for such assay
    Patent number: 5019498
    Abstract: A high molecular hyaluronic acid which is an important factor in the diagnosis of inflammations such as rheumatism or diseases such as cancer is assayed as a complex of sandwich structure in which a hyaluronic acid binding protein is coupled to the hyaluronic acid of interest at two or more sites of binding without the need to employ a competitive reaction as in the prior art techniques of assay. The assay method of the present invention does not require a purified form of hyaluronic acid as a reagent and permits as small as 10 ng of a high molecular hyaluronic acid to be detected or quantified by a very simple operation.
    Type: Grant
    Filed: March 1, 1988
    Date of Patent: May 28, 1991
    Assignee: Chugai Seiyaku Kabushiki Kaiska
    Inventor: Kenji Chichibu
  • Method for quantitative determination of an antigenic substance
    Patent number: 4091089
    Abstract: A method for the quantitative determination of antigenic substance without any confirmation test which comprises adding to a sample to be assayed an exogenous antigenic substance in a certain amount, combining the resulting mixture with an antibody specific to the antigenic substance to cause antigen-antibody reaction and measuring the amount of the precipitates formed, and a diagnostic kit for practicing the method are disclosed.
    Type: Grant
    Filed: March 31, 1976
    Date of Patent: May 23, 1978
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kenji Chichibu, Kiyoshige Wakabayashi