Abstract: An inlet-outlet valve device includes a main body configured in such a manner that an air tube having an air flow passage is coupled to the main body and a first securing portion and a second securing portion secured to a retaining member located inside a seat. The first securing portion is secured to a first position on the retaining member with a first securing portion fastening member. The second securing portion is secured to a second position on the retaining member via a second securing portion fastening member. The second securing portion includes an insertion hole through which the second securing portion fastening member is inserted. The insertion hole is an elongated hole extending in a direction that connects the first securing portion and the second securing portion to each other.

Abstract: A vehicle seat device includes a fixed base, a movable base, a paddle, and an air pack. When a side airbag arranged in the seat is deployed, the expanding side airbag presses and pivots the movable base and allows for a deployment of the side airbag. The paddle is configured to change a seat support form when pressed and pivoted by the air pack. The movable base pivots about a first pivot axis relative to the fixed base. The paddle pivots about a second pivot axis relative to the movable base. The first pivot axis and the second pivot axis are arranged at different locations.

Abstract: Methods of diagnosing, confirming a diagnosis of, and determining a predisposition for a bipolar disorder in a subject are provided. An amount of at least one of biomarker from the cerebrospinal fluid and/or serum of a subject is measured, for example, isocitric acid. The amount of the at least one biomarker can be compared with a control amount of the at least one biomarker in a corresponding sample collected from a subject without the bipolar disorder. An increase or decrease in the amount of the particular biomarker or biomarkers measured can be indicative that the subject has the bipolar disorder or a predisposition for the bipolar disorder. Methods of identifying a compound for preventing and/or treating a bipolar disorder are also provided based on the expression level of an isocitric acid dehydrogenase 3 alpha and/or beta-subunit gene, and/or based on one or more metabolite biomarker.

Abstract: A coil component includes a drum core including a winding core portion and a flange portion disposed on an end portion thereof the winding core portion in its axial direction, a planar core having a lower principal surface, and a wire wound around the winding core portion. The flange portion includes an inner end surface, an outer end surface, a bottom surface, and a top surface. The inner end surface positions the end portion of the winding core portion. The bottom surface links the inner end surface and the outer end surface and placed so as to face a mounting substrate side when being mounted. The lower principal surface of the planar core is fixed to the top surface with an adhesive interposed therebetween. The top surface includes a protrusion with a vertex positioned closer to the inner end surface than to the outer end surface.

Abstract: This invention provides methods for preventing, mitigating, ameliorating and/or controlling psychiatric disorders, including depression, major depression, bipolar disorder, schizophrenia and substance abuse (including addiction and dependence) by administration of an agent that increases epoxy-fatty acids (e.g., an inhibitor of soluble epoxide hydrolase), as sole active agent or in combination with another agent (e.g., an antidepressant, an antipsychotic, an anxiolytic). When co-administered in combination with another agent, one or both agent may be administered at a subtherapeutic dose.

Abstract: An air pressure control device of a vehicle seat includes: a bulging shape forming unit configured to form a bulging shape on a seat surface by expanding air bags configured to be provided inside a seat; a bulging shape moving unit configured to move a position of the bulging shape formed on the seat surface by each corresponding air bag by sequentially expanding and contracting a plurality of air bags aligned in a direction along the seat surface in an arrangement direction of the air bags; and a pumping capacity adjusting unit configured to increase a pumping capacity of an air pump that pumps air into each air bag as a protrusion amount of the corresponding bulging shape increases when a formation position of the bulging shape is moved.

Abstract: A mobile robot 1 having a plurality of kinds of moving forms includes a body unit 11 having a front face and a back face, four limb units 12 having a plurality of limb-side drive shafts, and front end tools 13 provided on a front end side of the limb units 12. A base end side of the limb unit 12 is connected to the body unit 11. The four limb units 12 are the same units. The body unit 11 and the four limb units 12 are movable by switching a front face side and a back face side so that a moving operation of the front face side and a moving operation of the back face side are symmetrical across the center of a thickness direction of the body unit 11.

Abstract: Provided is a novel compound having rapid and long-lasting therapeutic effects on diseases exhibiting depressive symptoms. Specifically, provided are an agent for prevention and/or treatment of a depressive symptom, consisting of R(?)-ketamine or a pharmacologically acceptable salt thereof, and a pharmaceutical composition for prevention and/or treatment of a depressive symptom, comprising R(?)-ketamine or a pharmacologically acceptable salt thereof in an effective amount for reducing a depressive symptom, and being substantially free of S(+)-ketamine, and a pharmacologically acceptable salt thereof.

Abstract: A medicinal preparation for preventing and/or treating psychoneurotic diseases such as integration dysfunction and Alzheimer's disease which contains tropisetron or its pharmaceutically acceptable salt as the active ingredient.

Abstract: A control device calculates an estimate of negative intake pressure based on the relationship between the rotation speed of a crankshaft and a throttle opening degree (Step S24). Then, the control device sets the estimate PE of the negative intake pressure, which is calculated in Step S24, to a greater value as combustion efficiency of CNG used in engine operation becomes higher (Step S25). When the corrected estimate PE of the negative intake pressure becomes smaller than or equal to a reference value PTh (Step S26: YES), the control device starts a negative pressure recovery procedure (Step S27).

Abstract: A seat support device includes a base, a paddle, an airbag, and a cable. The base is fixed to an inner side of a seat. The paddle is movable toward and away from the base. The airbag is arranged between the base and the paddle. The airbag pushes a seat pad of the seat with the paddle when deployed. The cable includes a first end engaged with the base and a second end engaged with the paddle.

Abstract: Provided is a novel compound having rapid and long-lasting therapeutic effects on diseases exhibiting depressive symptoms. Specifically, provided are an agent for prevention and/or treatment of a depressive symptom, consisting of R(?)-ketamine or a pharmacologically acceptable salt thereof, and a pharmaceutical composition for prevention and/or treatment of a depressive symptom, comprising R(?)-ketamine or a pharmacologically acceptable salt thereof in an effective amount for reducing a depressive symptom, and being substantially free of S(+)-ketamine, and a pharmacologically acceptable salt thereof.

Abstract: An air pressure control device of a vehicle seat includes: a bulging shape forming unit configured to form a bulging shape on a seat surface by expanding air bags configured to be provided inside a seat; a bulging shape moving unit configured to move a position of the bulging shape formed on the seat surface by each corresponding air bag by sequentially expanding and contracting a plurality of air bags aligned in a direction along the seat surface in an arrangement direction of the air bags; and a pumping capacity adjusting unit configured to increase a pumping capacity of an air pump that pumps air into each air bag as a protrusion amount of the corresponding bulging shape increases when a formation position of the bulging shape is moved.

Abstract: A mobile robot 1 having a plurality of kinds of moving forms includes a body unit 11 having a front face and a back face, four limb units 12 having a plurality of limb-side drive shafts, and front end tools 13 provided on a front end side of the limb units 12. A base end side of the limb unit 12 is connected to the body unit 11. The four limb units 12 are the same units. The body unit 11 and the four limb units 12 are movable by switching a front face side and a back face side so that a moving operation of the front face side and a moving operation of the back face side are symmetrical across the center of a thickness direction of the body unit 11.

Abstract: A pneumatic pressure control method for a vehicle seat includes: repeatedly detecting an internal pressure of a bladder provided inside the vehicle seat at intervals; correcting the internal pressure of the bladder based on a differential pressure between a detection value and a target value; and lengthening a detection interval to detect the internal pressure depending on a time elapsing from starting of the vehicle.

Abstract: A control device calculates an estimate of negative intake pressure based on the relationship between the rotation speed of a crankshaft and a throttle opening degree (Step S24). Then, the control device sets the estimate PE of the negative intake pressure, which is calculated in Step S24, to a greater value as combustion efficiency of CNG used in engine operation becomes higher (Step S25). When the corrected estimate PE of the negative intake pressure becomes smaller than or equal to a reference value PTh (Step S26: YES), the control device starts a negative pressure recovery procedure (Step S27).

Abstract: A mobile robot 1 having a plurality of kinds of moving forms includes a body unit 11 having a front face and a back face, four limb units 12 having a plurality of limb-side drive shafts, and front end tools 13 provided on a front end side of the limb units 12. A base end side of the limb unit 12 is connected to the body unit 11. The four limb units 12 are the same units. The body unit 11 and the four limb units 12 are movable by switching a front face side and a back face side so that a moving operation of the front face side and a moving operation of the back face side are symmetrical across the center of a thickness direction of the body unit 11.

Abstract: Methods of diagnosing, confirming a diagnosis of, and determining a predisposition for a bipolar disorder in a subject are provided. An amount of at least one of biomarker from the cerebrospinal fluid and/or serum of a subject is measured, for example, isocitric acid. The amount of the at least one biomarker can be compared with a control amount of the at least one biomarker in a corresponding sample collected from a subject without the bipolar disorder. An increase or decrease in the amount of the particular biomarker or biomarkers measured can be indicative that the subject has the bipolar disorder or a predisposition for the bipolar disorder. Methods of identifying a compound for preventing and/or treating a bipolar disorder are also provided based on the expression level of an isocitric acid dehydrogenase 3 alpha and/or beta-subunit gene, and/or based on one or more metabolite biomarker.

Abstract: A fuel supply apparatus is constructed such that an engine fuel to be supplied by injection to an internal combustion engine can be selectively switched to a first fuel or a second fuel. The fuel supply apparatus is equipped with a control unit that performs air-fuel ratio learning related to the injection amount of the engine fuel such that the actual air-fuel ratio detected by an air-fuel ratio sensor installed in the internal combustion engine agrees with a target air-fuel ratio. During the operation with the first fuel, the control device permits the switching of the engine fuel from the first fuel to the second fuel after a condition that includes the completion of the air-fuel ratio learning related to the first fuel is met.

Abstract: Provided is a novel compound having rapid and long-lasting therapeutic effects on diseases exhibiting depressive symptoms. Specifically, provided are an agent for prevention and/or treatment of a depressive symptom, consisting of R(?)-ketamine or a pharmacologically acceptable salt thereof, and a pharmaceutical composition for prevention and/or treatment of a depressive symptom, comprising R(?)-ketamine or a pharmacologically acceptable salt thereof in an effective amount for reducing a depressive symptom, and being substantially free of S(+)-ketamine, and a pharmacologically acceptable salt thereof.