Abstract: Provided are a cancer therapeutic drug comprising a compound which inhibits GPX4 as an active ingredient, the cancer therapeutic drug treating cancer containing a cancer cell having a suppressed function of a SWI/SNF complex factor detected; and a method for predicting sensitivity of a cancer cell to a GPX4 inhibitor, the method comprising the step of predicting a cancer cell having a suppressed function of a SWI/SNF complex factor detected in the cancer cell, as having sensitivity to the GPX4 inhibitor.

Abstract: Provided is a method for predicting sensitivity of a cancer cell to a helicase inhibitor, the method comprising the step of: predicting a cancer cell having at least one mutation detected selected from the first group consisting of TTK mutation and RAD 50 mutation, as having sensitivity to a helicase inhibitor, or predicting a cancer cell having at least one mutation detected selected from the second group consisting of RAD 50 mutation, MRE 11 mutation, NBN mutation, DNA 2 mutation and RBBP 8 mutation, as having sensitivity to a helicase inhibitor.

Abstract: A drive rotor has a coupled portion to which a coupling portion extending from a rotary shaft is loosely fitted. A driven rotor can be engaged with the drive rotor with respect to a rotating direction of the drive rotor. A restricting member is fixed to the rotary shaft so as to be integrally rotatable. In the case that the drive rotor is inclined with respect to the rotary shaft, the restricting member can be brought into contact with the drive rotor. Accordingly, it is possible to suppress an excessive looseness in a coupling mechanism.

Abstract: A drive rotor has a coupled portion to which a coupling portion extending from a rotary shaft is loosely fitted. A driven rotor can be engaged with the drive rotor with respect to a rotating direction of the drive rotor. A restricting member is fixed to the rotary shaft so as to be integrally rotatable. In the case that the drive rotor is inclined with respect to the rotary shaft, the restricting member can be brought into contact with the drive rotor. Accordingly, it is possible to suppress an excessive looseness in a coupling mechanism.

Abstract: In a motor device for vehicles, a brush holder is interposed between a motor yoke housing and a reduction gear unit housing has a holder body and a connector unit integrally formed with each other. The connector unit holds therein connector terminals having base ends connected to brushes. A sealing cover is molded integrally on the holder body and the base ends of the connector terminals. The sealing cover seals insides of the yoke housing and the gear housing water-tightly from the outside. The sealing cover is preferably made of rubber, elastomer or adhesive resin, and formed with the brush holder by two-color molding. The sealing cover has a cylindrical cover part extending from the connector unit, and the motor device is mounted in a vehicle door with the cylindrical cover part being attached to the vehicle door for electrical connection with an external power source.

Abstract: In a motor device for vehicles, a brush holder is interposed between a motor yoke housing and a reduction gear unit housing has a holder body and a connector unit integrally formed with each other. The connector unit holds therein connector terminals having base ends connected to brushes. A sealing cover is molded integrally on the holder body and the base ends of the connector terminals. The sealing cover seals insides of the yoke housing and the gear housing water-tightly from the outside. The sealing cover is preferably made of rubber, elastomer or adhesive resin, and formed with the brush holder by two-color molding. The sealing cover has a cylindrical cover part extending from the connector unit, and the motor device is mounted in a vehicle door with the cylindrical cover part being attached to the vehicle door for electrical connection with an external power source.