Abstract: The object of the present invention is to improve the dissolution and the absorption of (S)-1-(3-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl-1-pyrrolidinyl)-2-propen-1-one effective as an antitumor agent from a pharmaceutical formulation comprising the same. Provided is a pharmaceutical composition comprising (S)-1-(3-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl-1-pyrrolidinyl)-2-propen-1-one in combination with sodium alkyl sulfate having an alkyl group containing 10 to 18 carbon atoms, in particular, with sodium lauryl sulfate.

Abstract: The object of the present invention is to improve the dissolution and the absorption of (S)-1-(3-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl-1-pyrrolidinyl)-2-propen-1-one effective as an antitumor agent from a pharmaceutical formulation comprising the same. Provided is a pharmaceutical composition comprising (S)-1-(3-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl-1-pyrrolidinyl)-2-propen-1-one in combination with sodium alkyl sulfate having an alkyl group containing 10 to 18 carbon atoms, in particular, with sodium lauryl sulfate.

Abstract: The present invention provides a liposome having excellent lung migration ability that had not existed hitherto, by including GALA or Chol-GALA in the liposome. Furthermore, by using the liposome, a pulmonary delivery carrier having a stronger knockdown effect of siRNA when compared to existing carriers is provided.

Abstract: The present invention provides a liposome having excellent lung migration ability that had not existed hitherto, by including GALA or Chol-GALA in the liposome. Furthermore, by using the liposome, a pulmonary delivery carrier having a stronger knockdown effect of siRNA when compared to existing carriers is provided.

Abstract: A light receiving module for receiving a plurality of light rays that includes a first optical element having a plurality of light emitting sections, a second optical element having a plurality of light receiving sections, and a gradient index lens which condenses a plurality of light rays being output from the plurality of light emitting sections to the plurality of light receiving sections respectively, the gradient index lens being disposed between the first optical element and the second optical element.

Abstract: A terminal system has a mass spectrometric for inspecting of dangerous substances is installed in an inspection area, and a support system for determining whether or not a dangerous substance is present and identifying the type of the substance, based on the mass spectrometric data on the target element that has been measured by the mass spectrometric, is installed in a security service enterprise's office. Both systems are connected to each other via a communication network so that they can exchange information. Thus, the support system can send the determination result of dangerous substances and a precautions guide to the terminal system via the communication network.

Abstract: A method and apparatus for analyzing vapors generated from explosives in which vapors containing nitrogen monoxide and/or nitrogen dioxide are generated by decomposing explosives by increasing the temperature of the explosives, primary ions and neutral molecules are generated from air. The generated primary ions and the nitrogen monoxide and/or nitrogen dioxide contained in the generated vapors are allowed to react with each other in an area inhibited or prevented from being penetrated by the generated neutral molecules, and the nitrogen monoxide and/or nitrogen dioxide contained in the generated vapors is ionized. The ionized nitrogen monoxide and/or nitrogen dioxide is subjected to mass spectrometry, and an amount of the nitrogen monoxide and/or nitrogen dioxide contained in the generated vapors by decomposing the explosives is determined.

Abstract: The present invention provides a method for analyzing vapors generated from explosives, capable of collecting a sample with ease, and stably analyzing the vapors generated from explosives in a short time and with high accuracy, and an analysis apparatus to be used for the analysis method.

Abstract: A terminal system 1 which has mass spectrometric means for inspecting for dangerous substances is installed in an inspection area, and a support system 2 for determining whether or not a dangerous substance is present and identifying the type of the substance, based on the mass spectrometric data on the target element that has been measured by said mass spectrometric means, is installed in a security service enterprise's office. Both systems are connected to each other via a communication network so that they can exchange information. Thus, the support system 2 can send the determination result of dangerous substances and a precautions guide to the terminal system 1 via said communication network 3. The security service enterprise conducts equipment management, such as maintenance and checkups, and operation administration of the security system, thereby making it easier for a user to introduce this security system.

Abstract: An image forming apparatus according to the present invention includes a photoreceptor, an image forming unit for forming a toner image on the photoreceptor, an intermediate transfer medium to which the toner image formed on the photoreceptor is transferred at a transfer position and from which the transferred toner image is transferred to a sheet, a cleaning unit for removing toner on the intermediate transfer medium, and a controller for providing control for the sequence of activating a preliminary cleaning of the transfer belt for a predetermined time period, starting image formation after the preliminary cleaning is terminated, actuating a subsequent cleaning after termination of the transfer process, and then starting image formation in response to an image formation start signal output during the subsequent cleaning.