Patents by Inventor Kenji Moroshima

Kenji Moroshima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR CONTROLLED RELEASE OF AN ACID-UNSTABLE PHYSIOLOGICALLY ACTIVE SUBSTANCE
    Publication number: 20120003311
    Abstract: It is an object of the present invention, in the case of a controlled-release pharmaceutical composition, particularly a pulsed-release pharmaceutical composition, containing an acid-unstable physiologically active substance, to provide a pharmaceutical composition having little variation in dissolution lag time and high reliability of dissolution characteristics. The present invention discloses a controlled-release pharmaceutical composition comprising: 1) a core containing an acid-unstable physiologically active substance and a disintegrant; and 2) a release-controlling coating which covers the core, and which contains a water-insoluble polymer, an enteric polymer and a hydrophobic wax.
    Type: Application
    Filed: October 6, 2006
    Publication date: January 5, 2012
    Applicant: EISAI R&D MANAGEMENT CO., LTD.
    Inventors: Takashi Yoshitake, Mitsuru Mizuno, Kenji Moroshima, Shigeru Aoki
  • EXTENDED RELEASE FORMULATIONS OF A PROTON PUMP INHIBITOR
    Publication number: 20100105738
    Abstract: The invention provides extended release formulations of proton pump inhibitor, such as an extended release formulation of rabeprazole, comprising an amount of rabeprazole between 30 and 90 mg rabeprazole and having an AUC of between 900 and 1750 ng*hr/mL and other properties.
    Type: Application
    Filed: October 4, 2007
    Publication date: April 29, 2010
    Inventors: Mitsuru Mizuno, Shigeru Aoki, Kiyoshi Iwamoto, Kenji Moroshima, Yasuhiro Zaima, Manabu Murakami, Yukio Horai, Takashi Seno, Norihiro Ueda
  • Controlled-Release Pharmaceutical Composition and Method for Producing the Same
    Publication number: 20080095839
    Abstract: It is an object of the present invention, in the case of a controlled-release pharmaceutical composition, particularly a pulsed-release pharmaceutical composition, containing an acid-unstable physiologically active substance, to provide a pharmaceutical composition having little variation in dissolution lag time and high reliability of dissolution characteristics. The present invention discloses a controlled-release pharmaceutical composition comprising: 1) a core containing an acid-unstable physiologically active substance and a disintegrant; and 2) a release-controlling coating which covers the core, and which contains a water-insoluble polymer, an enteric polymer and a hydrophobic wax.
    Type: Application
    Filed: March 23, 2005
    Publication date: April 24, 2008
    Applicant: EISAI R&D MANAGEMENT CO., LTD.
    Inventors: Takashi Yoshitake, Mitsuru Mizuno, Kenji Moroshima, Shigeru Aoki
  • Controlled-release pharmaceutical composition and method for producing the same
    Publication number: 20070110806
    Abstract: It is an object of the present invention, in the case of a controlled-release pharmaceutical composition, particularly a pulsed-release pharmaceutical composition, containing an acid-unstable physiologically active substance, to provide a pharmaceutical composition having little variation in dissolution lag time and high reliability of dissolution characteristics. The present invention discloses a controlled-release pharmaceutical composition comprising: 1) a core containing an acid-unstable physiologically active substance and a disintegrant; and 2) a release-controlling coating which covers the core, and which contains a water-insoluble polymer, an enteric polymer and a hydrophobic wax.
    Type: Application
    Filed: October 6, 2006
    Publication date: May 17, 2007
    Applicant: EISAI R&D MANAGEMENT CO., LTD.
    Inventors: Takashi Yoshitake, Mitsuru Mizuno, Kenji Moroshima, Shigeru Aoki