Patents by Inventor Kenji Sugita

Kenji Sugita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aromatic-sulfonamide-type hydroxamic acid derivative
    Patent number: 5534654
    Abstract: A novel hydroxamic acid compound of the formula: ##STR1## or a pharmaceutically acceptable salt thereof having cell growth inhibition, vascularization inhibition activities and the like.The compounds of the present invention possess inhibitory activities against the growth of vascular endothelial cells and the expression of lymphocyte adhesive factors and the detransforming activity of cells transformed by ras gene, and inhibit the cell growth and are effective on inflammation and tumor.
    Type: Grant
    Filed: August 3, 1993
    Date of Patent: July 9, 1996
    Assignee: Shionogi & Co., Ltd.
    Inventors: Mitsuaki Ohtani, Hitoshi Arita, Kenji Sugita, Takaharu Matsuura, Kazuhiro Shirahase
  • Cyclic tetrapeptide and process for preparing the same
    Patent number: 5112944
    Abstract: A cyclic tetrapeptide having the formula (I): ##STR1## wherein n is 4 or 3 and a process for preparing the above cyclic tetrapeptide. The cyclic tetrapeptide of the present invention inhibits transformation of cells caused by oncogenes and possesses activities for recovering to a normal cell and for inhibiting proliferation of carcinoma cells. Therefore, the cyclic tetrapeptide of the present invention is useful for an active ingredient of an antitumor agent.
    Type: Grant
    Filed: June 12, 1990
    Date of Patent: May 12, 1992
    Assignee: Shionogi & Co., Ltd.
    Inventors: Kenji Sugita, Hiroshi Itazaki, Koichi Matsumoto, Yoshimi Kawamura