Patents by Inventor Kenji Takaya

Kenji Takaya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10696707
    Abstract: The present invention is the following Amphotericin B derivative: wherein each symbol is defined in description. The compound of the present invention has 16th position (X) is urea structure, cyclic structure, hydroxyalkyl or substituted monoalkylcarbamoyl. The compound of the present invention has antifungal activity.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: June 30, 2020
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Keisuke Miyazaki, Kenji Takaya, Takafumi Ohara, Hideki Sugimoto, Manabu Fujitani, Yuki Ogata, Naoyuki Suzuki
  • Publication number: 20190135847
    Abstract: The present invention is the following Amphotericin B derivative: wherein each symbol is defined in description. The compound of the present invention has 16th position (X) is urea structure, cyclic structure, hydroxyalkyl or substituted monoalkylcarbamoyl. The compound of the present invention has antifungal activity.
    Type: Application
    Filed: December 28, 2018
    Publication date: May 9, 2019
    Applicant: Shionogi & Co., Ltd.
    Inventors: Keisuke MIYAZAKI, Kenji TAKAYA, Takafumi OHARA, Hideki SUGIMOTO, Manabu FUJITANI, Yuki OGATA, Naoyuki SUZUKI
  • Patent number: 10246478
    Abstract: The present invention is the following Amphotericin B derivative: wherein each symbol is defined in description. The compound of the present invention has 16th position (X) is urea structure, cyclic structure, hydroxyalkyl or substituted monoalkylcarbamoyl. The compound of the present invention has antifungal activity.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: April 2, 2019
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Keisuke Miyazaki, Kenji Takaya, Takafumi Ohara, Hideki Sugimoto, Manabu Fujitani, Yuki Ogata, Naoyuki Suzuki
  • Publication number: 20180271816
    Abstract: Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.
    Type: Application
    Filed: May 29, 2018
    Publication date: September 27, 2018
    Inventors: Richard B. Silverman, Kenji Takaya, Hoang V. Le, Jose I. Juncosa
  • Patent number: 9993449
    Abstract: Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: June 12, 2018
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Richard B. Silverman, Kenji Takaya, Hoang V. Le, Jose I. Juncosa
  • Patent number: 9815835
    Abstract: This invention provides compounds having antiviral activities especially inhibiting activity for influenza virus, more preferably provides substituted 3-hydroxy-4-pyridone derivatives having cap-dependent endonuclease inhibitory activity.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: November 14, 2017
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Toshiyuki Akiyama, Kenji Takaya, Makoto Kawai, Yoshiyuki Taoda, Minako Mikamiyama, Kenji Morimoto, Kenji Tomita, Hidenori Mikamiyama, Naoyuki Suzuki
  • Publication number: 20170239202
    Abstract: Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.
    Type: Application
    Filed: May 4, 2017
    Publication date: August 24, 2017
    Inventors: Richard B. Silverman, Kenji Takaya, Hoang V. Le, Jose I. Juncosa
  • Publication number: 20170190729
    Abstract: The present invention is the following Amphotericin B derivative: wherein each symbol is defined in description. The compound of the present invention has 16th position (X) is urea structure, cyclic structure, hydroxyalkyl or substituted monoalkylcarbamoyl. The compound of the present invention has antifungal activity.
    Type: Application
    Filed: June 12, 2015
    Publication date: July 6, 2017
    Applicant: Shionogi & Co., Ltd.
    Inventors: Keisuke MIYAZAKI, Kenji TAKAYA, Takafumi OHARA, Hideki SUGIMOTO, Manabu FUJITANI, Yuki OGATA, Naoyuki SUZUKI
  • Patent number: 9670141
    Abstract: Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.
    Type: Grant
    Filed: October 10, 2016
    Date of Patent: June 6, 2017
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Richard B. Silverman, Kenji Takaya, Hoang V. Le, Jose I. Juncosa
  • Publication number: 20170101364
    Abstract: Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.
    Type: Application
    Filed: October 10, 2016
    Publication date: April 13, 2017
    Inventors: Richard B. Silverman, Kenji Takaya, Hoang V. Le, Jose I. Juncosa
  • Publication number: 20170066759
    Abstract: The present invention is related to a compound represented by formula (I) wherein R1 is a hydrogen atom, substituted or unsubstituted alkyl, substituted or unsubstituted aromatic carbocyclyl, or the like; X is —N(R3)—, —O—, or —S—; Y is ?C(R4)—, or ?N—; Z is —N(R7)—, —O—, or —S—; R2 is substituted or unsubstituted alkyloxy, or the like, or a group represented by the following formula: —(CR2aR2b)n—R2c, wherein R2a is each independently a hydrogen atom, halogen, or the like; R2b is each independently a hydrogen atom, halogen, or the like; R2a and R2b which are attached to the same carbon atom may be taken together to form oxo, a substituted or unsubstituted non-aromatic carbocycle, or the like; two of R2a which are attached to the adjacent carbon atoms and/or two of R2b which are attached to the adjacent carbon atoms may be taken together to form a bond; R2c is substituted or unsubstituted aromatic carbocyclyl, or the like; n is an integer from 1 to 3; R3 and R7 are each independently a hydrogen atom, subs
    Type: Application
    Filed: September 30, 2016
    Publication date: March 9, 2017
    Inventors: Akira YUKIMASA, Naotake KOBAYASHI, Kenji TAKAYA, Yoshio HATO
  • Publication number: 20160368921
    Abstract: This invention provides compounds having antiviral activities especially inhibiting activity for influenza virus, more preferably provides substituted 3-hydroxy-4-pyridone derivatives having cap-dependent endonuclease inhibitory activity.
    Type: Application
    Filed: August 31, 2016
    Publication date: December 22, 2016
    Inventors: Toshiyuki AKIYAMA, Kenji Takaya, Makoto Kawai, Yoshiyuki Taoda, Minako Mikamiyama, Kenji Morimoto, Kenji Tomita, Hidenori Mikamiyama, Naoyuki Suzuki
  • Patent number: 9499533
    Abstract: The present invention is related to a compound represented by formula (I) wherein R1 is a hydrogen atom, substituted or unsubstituted alkyl, substituted or unsubstituted aromatic carbocyclyl, or the like; X is —N(R3)—, —O—, or —S—; Y is ?C(R4)—, or ?N—; Z is —N(R7)—, —O—, or —S—; R2 is substituted or unsubstituted alkyloxy, or the like, or a group represented by the following formula: —(CR2aR2b)n—R2c, wherein R2a is each independently a hydrogen atom, halogen, or the like; R2b is each independently a hydrogen atom, halogen, or the like; R2a and R2b which are attached to the same carbon atom may be taken together to form oxo, a substituted or unsubstituted non-aromatic carbocycle, or the like; two of R2a which are attached to the adjacent carbon atoms and/or two of R2b which are attached to the adjacent carbon atoms may be taken together to form a bond; R2c is substituted or unsubstituted aromatic carbocyclyl, or the like; n is an integer from 1 to 3; R3 and R7 are each independently a hydrogen atom, subs
    Type: Grant
    Filed: March 26, 2013
    Date of Patent: November 22, 2016
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Akira Yukimasa, Naotake Kobayashi, Kenji Takaya, Yoshio Hato
  • Patent number: 9469638
    Abstract: This invention provides compounds having antiviral activities especially inhibiting activity for influenza virus, more preferably provides substituted 3-hydroxy-4-pyridone derivatives having cap-dependent endonuclease inhibitory activity.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: October 18, 2016
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Toshiyuki Akiyama, Kenji Takaya, Makoto Kawai, Yoshiyuki Taoda, Minako Mikamiyama, Kenji Morimoto, Kenji Tomita, Hidenori Mikamiyama, Naoyuki Suzuki
  • Publication number: 20150065485
    Abstract: This invention provides compounds having antiviral activities especially inhibiting activity for influenza virus, more preferably provides substituted 3-hydroxy-4-pyridone derivatives having cap-dependent endonuclease inhibitory activity.
    Type: Application
    Filed: November 7, 2014
    Publication date: March 5, 2015
    Inventors: Toshiyuki Akiyama, Kenji Takaya, Makoto Kawai, Yoshiyuki Taoda, Minako Mikamiyama, Kenji Morimoto, Chika Kageyama, Kenji Tomita, Hidenori Mikamiyama, Naoyuki Suzuki
  • Publication number: 20150038483
    Abstract: The present invention is related to a compound represented by formula (I) wherein R1 is a hydrogen atom, substituted or unsubstituted alkyl, substituted or unsubstituted aromatic carbocyclyl, or the like; X is —N(R3)—, —O—, or —S—; Y is ?C(R4)—, or ?N—; Z is —N(R7)—, —O—, or —S—; R2 is substituted or unsubstituted alkyloxy, or the like, or a group represented by the following formula: —(CR2aR2b)n—R2c, wherein R2a is each independently a hydrogen atom, halogen, or the like; R2b is each independently a hydrogen atom, halogen, or the like; R2a and R2b which are attached to the same carbon atom may be taken together to form oxo, a substituted or unsubstituted non-aromatic carbocycle, or the like; two of R2a which are attached to the adjacent carbon atoms and/or two of R2b which are attached to the adjacent carbon atoms may be taken together to form a bond; R2c is substituted or unsubstituted aromatic carbocyclyl, or the like; n is an integer from 1 to 3; R3 and R7 are each independently a hydrogen atom, sub
    Type: Application
    Filed: March 26, 2013
    Publication date: February 5, 2015
    Inventors: Akira Yukimasa, Naotake Kobayashi, Kenji Takaya, Yoshio Hato
  • Patent number: 8927710
    Abstract: This invention provides compounds having antiviral activities especially inhibiting activity for influenza virus, more preferably provides substituted 3-hydroxy-4-pyridone derivatives having cap-dependent endonuclease inhibitory activity.
    Type: Grant
    Filed: June 14, 2010
    Date of Patent: January 6, 2015
    Assignee: Shionogi & Co., Ltd.
    Inventors: Toshiyuki Akiyama, Kenji Takaya, Makoto Kawai, Yoshiyuki Taoda, Minako Mikamiyama, Kenji Morimoto, Chika Kageyama, Kenji Tomita, Hidenori Mikamiyama, Naoyuki Suzuki
  • Patent number: 8889674
    Abstract: The present invention discloses novel piperidine and pyrrolidine derivatives having NPY Y5 receptor antagonistic activity. Specifically, the present invention discloses a compound represented by the formula (I), a pharmaceutically acceptable salt or a solvate thereof: wherein A is substituted or unsubstituted monocyclic aryl or monocyclic heterocyclyl; X is a single bond or C(?O); Y is a single bond, CR5R6NR7 or C(?O)NR7; R1 and R2 are independently hydrogen or substituted or unsubstituted alkyl; R3 is substituted or unsubstituted aryl or heterocyclyl; R4 is halogen, substituted or unsubstituted alkyl, alkoxy, aryloxy or heterocyclyloxy, etc.; p is an integer of 0 to 2; q is 0 or 1; m is 0 or 1; n is an integer of 0 to 5; and B is aromatic carbocycle, monocyclic heterocycle or bicyclic fused hetero ring.
    Type: Grant
    Filed: March 5, 2010
    Date of Patent: November 18, 2014
    Assignee: Shionogi & Co., Ltd.
    Inventors: Masahiro Sakagami, Hitomi Araki, Hiroshi Hashizume, Hiroshi Yari, Kenji Takaya
  • Patent number: D906261
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: December 29, 2020
    Assignee: SMC CORPORATION
    Inventors: Kenji Suda, Daisuke Takaya
  • Patent number: D906262
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: December 29, 2020
    Assignee: SMC CORPORATION
    Inventors: Kenji Suda, Daisuke Takaya