Abstract: A candesartan cilexetil-containing preparation contains candesartan cilexetil and lauromacrogol. The lauromacrogol may be contained at a ratio of 2.4 parts by weight or less with respect to 100 parts by weight of the candesartan cilexetil-containing preparation. The candesartan cilexetil-containing preparation may further contain at least one kind of pharmacologically acceptable additives among a diluent, a disintegrant and a binder.

Abstract: A production method of pharmaceutical composition contains candesartan cilexetil, comprising dissolving a water-soluble polymer and a sugar alcohol to purified water and dispersing candesartan cilexetil to prepare a dispersion liquid of candesartan cilexetil, granulating by a wet process using the dispersion liquid together with a powdery additive to obtain a granulated product, drying the granulated product, particle size regulating the granulated product; and tableting the granulated product, wherein the dispersion liquid contains the amount of water-soluble polymer within a range of 0.05 parts by weight or more and 0.5 parts by weight or less, based on 100 parts by weight of the pharmaceutical composition, and the dispersion liquid contains the amount of sugar alcohol within a range of 5 parts by weight or more and 20 parts by weight or less, based on 100 parts by weight of the pharmaceutical composition.

Abstract: The present invention provides a pharmaceutical composition containing candesartan cilexetil, which is produced by wet granulation using a dispersion liquid of candesartan cilexetil together with a powdery additive. The dispersion liquid may also contain a water-soluble polymer, a sugar alcohol, or a stabilizer, and the water-soluble polymer may be hydroxypropylcellulose. The sugar alcohol may be mannitol. In addition, the stabilizer may be lauromacrogol.

Abstract: A candesartan cilexetil-containing preparation contains candesartan cilexetil and lauromacrogol. The lauromacrogol may be contained at a ratio of 2.4 parts by weight or less with respect to 100 parts by weight of the candesartan cilexetil-containing preparation. The candesartan cilexetil-containing preparation may further contain at least one kind of pharmacologically acceptable additives among a diluent, a disintegrant and a binder.