Patents by Inventor Kenjiro Hanaoka

Kenjiro Hanaoka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150212073
    Abstract: A compound represented by the formula (I) [R1 represents hydrogen atom or a substituent; R2, R3, R6, and R7 represent hydrogen atom, an alkyl group, a halogen atom, or a hydrophilic substituent; R4 and R5 represent an alkyl group or an aryl group; R8 and R9 represent a group cleaved by contact with an object substance for measurement; and X represents silicon atom, germanium atom, or tin atom] or a salt thereof, which is useful as a fluorescent probe that emits red fluorescence by contact with an object substance for measurement.
    Type: Application
    Filed: February 15, 2013
    Publication date: July 30, 2015
    Inventors: Tetsuo Nagano, Kenjiro Hanaoka, Kazuhisa Hirabayashi, Yuko Toki
  • Publication number: 20140342384
    Abstract: A compound represented by the formula (I) (R1 represents a substituent on the benzene ring; R2 represents a monovalent substituent; R3 and R4 represent hydrogen atom, or an alkyl group; R5 and R6 represent an alkyl group, or an aryl group; R7 and R8 represent hydrogen atom, or an alkyl group; R9 and R10 represent hydrogen atom, or a monovalent substituent; and X represents silicon atom, germanium atom, or tin atom), or a salt thereof.
    Type: Application
    Filed: February 17, 2012
    Publication date: November 20, 2014
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Tetsuo Nagano, Kenjiro Hanaoka, Yuichiro Koide, Takahiro Egawa, Yu Kushida
  • Publication number: 20140057312
    Abstract: A compound represented by the formula (I) (one of substituents represented by R1 is a trapping group for an object substance for measurement; R2 and R3 represent hydrogen, alkyl, or halogen; R4 and R5 represent alkyl or aryl; R6 and R7 represent hydrogen, alkyl, or halogen; R8 represents hydrogen, alkylcarbonyl, or alkylcarbonyloxymethyl, and X represents silicon, germanium, or tin, which can be used as a fluorescent probe that enables red color bioimaging using intramolecular photoinduced electron transfer.
    Type: Application
    Filed: February 17, 2012
    Publication date: February 27, 2014
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Tetsuo Nagano, Kenjiro Hanaoka, Yuichiro Koide, Takahiro Egawa
  • Publication number: 20130289256
    Abstract: A compound represented by the formula (I) (R1 represents hydrogen atom or a monovalent substituent; R2 and R3 represent hydrogen atom, an alkyl group, or a halogen atom; R4 and R5 represent an alkyl group or an aryl group; R6 and R7 represent hydrogen atom, an alkyl group, or a halogen atom; R8 represent hydroxy group or a dialkoxyboranetriyl group; and X represents silicon atom, germanium atom, or tin atom), which is a novel fluorophore usable as a mother nucleus of an off/on type fluorescent probe not utilizing the intramolecular photoinduced electron transfer.
    Type: Application
    Filed: January 19, 2012
    Publication date: October 31, 2013
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Tetsuo Nagano, Kenjiro Hanaoka, Yuichiro Koide, Takahiro Egawa, Kazuhisa Hirabayashi
  • Publication number: 20120065384
    Abstract: A fluorescent gadolinium complex compound comprising a residue of gadolinium.1,4,7,10-tetraazacyclododecane-N,N?,N?,N??-tetraacetic acid or a residue of gadolinium.diethylenetriaminepentaacetic acid bound covalently with a group represented by the following general formula (I) (R1 represents hydrogen atom or a substituent R2, R4, R5 and R7 represent hydrogen atom, a halogen atom or a C1-6 alkyl group, and R3 and R6 represent hydrogen atom, a halogen atom or a C1-6 alkyl group), which is easily taken up into cells and useful as a probe observable by the fluorescence method and MRI.
    Type: Application
    Filed: March 4, 2010
    Publication date: March 15, 2012
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Tetsuo Nagano, Kenjiro Hanaoka, Takehiro Yamane, Yasuaki Muramatsu