Patents by Inventor Kenjiro Mori

Kenjiro Mori has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10253153
    Abstract: The present invention provides a linker for solid phase synthesis of nucleic acid, which consists of a compound represented by the formula (I) or the formula (II), a support for solid phase synthesis of nucleic acid, which has a structure represented by the formula (III), and a production method of a nucleic acid, which uses the support: wherein each symbol is as defined in the SPECIFICATION.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: April 9, 2019
    Assignee: Nitto Denko Corporation
    Inventors: Eri Maeta, Kenjiro Mori, Shohei Horie, Takahiko Ito, Shoichiro Saito, Ryuhei Nagao
  • Patent number: 10138266
    Abstract: The invention provides a cut-out method capable of suppressing production of a byproduct, wherein the object RNA oligonucleotide is not cleaved from a universal linker, which is produced in cutting out the object RNA oligonucleotide from the universal support, and capable of increasing the yield of the object RNA oligonucleotide. The RNA oligonucleotide cut-out method includes a step of bringing a universal support supporting an RNA oligonucleotide in contact with an aqueous solution containing alkylamine and a monovalent inorganic salt.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: November 27, 2018
    Assignee: Nitto Denko Corporation
    Inventors: Shohei Horie, Tatsuya Konishi, Kenjiro Mori, Eri Maeta, Tsuyoshi Mukobata, Masafumi Iwamoto
  • Patent number: 9740541
    Abstract: An information processing apparatus includes a packet preprocessing unit configured to generate a packet process request when a packet is received; a CPU core configured to process the packet in response to the packet process request; a hardware element configured to generate a message including information identifying a predetermined event, in response to the predetermined event occurring in accordance with the processing of the packet, the hardware element being provided in the CPU core; and a message recording unit configured to record the message generated by the hardware element together with a count value of a timer.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: August 22, 2017
    Assignee: FUJITSU LIMITED
    Inventors: Shuji Takada, Takatoshi Fukuda, Kenjiro Mori
  • Patent number: 9619361
    Abstract: A performance profiling apparatus includes: a plurality of counters provided for a routine included in a program; a storage section configured to store an instruction of the program and an identification information indicating the routine of the program; a processor configured to read the instruction from the storage section and to execute a process according to the instruction; and a counter controller configured to, at the time of reading the instruction of the processor, receive the identification information of the instruction which is output from the storage section with the instruction and to instruct a first counter designated by the identification information to count up.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: April 11, 2017
    Assignee: FUJITSU LIMITED
    Inventors: Takatoshi Fukuda, Shuji Takada, Kenjiro Mori
  • Publication number: 20170002038
    Abstract: The invention provides a cut-out method capable of suppressing production of a byproduct, wherein the object RNA oligonucleotide is not cleaved from a universal linker, which is produced in cutting out the object RNA oligonucleotide from the universal support, and capable of increasing the yield of the object RNA oligonucleotide. The RNA oligonucleotide cut-out method includes a step of bringing a universal support supporting an RNA oligonucleotide in contact with an aqueous solution containing alkylamine and a monovalent inorganic salt.
    Type: Application
    Filed: June 17, 2016
    Publication date: January 5, 2017
    Applicant: Nitto Denko Corporation
    Inventors: Shohei HORIE, Tatsuya KONISHI, Kenjiro MORI, Eri MAETA, Tsuyoshi MUKOBATA, Masafumi IWAMOTO
  • Publication number: 20160311847
    Abstract: The present invention provides a linker for solid phase synthesis of nucleic acid, which consists of a compound represented by the formula (I) or the formula (II), a support for solid phase synthesis of nucleic acid, which has a structure represented by the formula (III), and a production method of a nucleic acid, which uses the support: wherein each symbol is as defined in the SPECIFICATION.
    Type: Application
    Filed: April 22, 2016
    Publication date: October 27, 2016
    Applicant: Nitto Denko Corporation
    Inventors: Eri MAETA, Kenjiro MORI, Shohei HORIE, Takahiko ITO, Shoichiro SAITO, Ryuhei NAGAO
  • Patent number: 9262122
    Abstract: In a multicore system in which a plurality of CPUs each including a cache memory share one main memory, a write buffer having a plurality of stages of buffers each holding data to be written to the main memory and an address of a write destination is provided between the cache memory and the main memory, and at the time of a write to the write buffer from the cache memory, an address of a write destination and the addresses stored in the buffers are compared, and when any of the buffers has an agreeing address, data is overwritten to this buffer, and the buffer is logically moved to a last stage.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: February 16, 2016
    Assignee: FUJITSU LIMITED
    Inventors: Takatoshi Fukuda, Shuji Takada, Kenjiro Mori
  • Publication number: 20150205648
    Abstract: An information processing apparatus includes a packet preprocessing unit configured to generate a packet process request when a packet is received; a CPU core configured to process the packet in response to the packet process request; a hardware element configured to generate a message including information identifying a predetermined event, in response to the predetermined event occurring in accordance with the processing of the packet, the hardware element being provided in the CPU core; and a message recording unit configured to record the message generated by the hardware element together with a count value of a timer.
    Type: Application
    Filed: March 31, 2015
    Publication date: July 23, 2015
    Inventors: Shuji Takada, Takatoshi Fukuda, Kenjiro Mori
  • Publication number: 20150152234
    Abstract: The present invention provides a porous resin bead of a copolymer composed of a monovinyl monomer unit and a crosslinking vinyl monomer unit, which has a group capable of binding with a carboxy group by a dehydration condensation reaction, wherein the amount of the crosslinking vinyl monomer is 18.5-55 mol % of the total monomer, and the median pore size of the porous resin bead is 60-300 nm.
    Type: Application
    Filed: December 3, 2014
    Publication date: June 4, 2015
    Inventors: Eri MAETA, Kenjiro MORI, Shohei HORIE
  • Patent number: 9045573
    Abstract: The present invention provides a solid-phase support for oligonucleotide synthesis for synthesizing long chain oligonucleotide, RNA oligonucleotide and modified oligonucleotide at high synthetic quantity and high purity with a low loading amount of a linker. Provided is a solid-phase support for oligonucleotide synthesis comprising a porous resin bead having a monovinyl monomer unit, a crosslinkable vinyl monomer unit and a polyethylene glycol unit and a cleavable linker loaded on its surface, the porous resin bead having a group capable of binding to a carboxy group by a dehydration condensation reaction on its surface, the cleavable linker having a carboxy group, wherein the carboxy group of the cleavable linker is bound to the group capable of binding to a carboxy group, by a dehydration condensation reaction, and a loading amount of the cleavable linker is 1 to 80 ?mol/g relative to the weight of the porous resin bead.
    Type: Grant
    Filed: May 23, 2013
    Date of Patent: June 2, 2015
    Assignee: Nitto Denko Corporation
    Inventors: Eri Maeta, Kenjiro Mori, Kazuya Miwa
  • Publication number: 20140297963
    Abstract: When an invalidation request is inputted from another processing device, a cache controller registers a set of an invalidation request address which the invalidation request has and an identifier of the other processing device which outputted the invalidation request in an invalidation history table. When a central processing unit attempts to read data at a first address not stored in a cache memory, if the first address is registered in the invalidation history table, the cache controller outputs a coherent read request containing the first address to the other processing device indicated by the identifier of the other processing device which outputted the invalidation request corresponding to the first address, or if the first address is not registered in the invalidation history table, the cache controller outputs a coherent read request containing the first address to all other processing devices.
    Type: Application
    Filed: February 17, 2014
    Publication date: October 2, 2014
    Applicant: FUJITSU LIMITED
    Inventors: Takatoshi FUKUDA, Kenjiro MORI, Shuji TAKADA
  • Publication number: 20140281059
    Abstract: In a multicore system in which a plurality of CPUs each including a cache memory share one main memory, a write buffer having a plurality of stages of buffers each holding data to be written to the main memory and an address of a write destination is provided between the cache memory and the main memory, and at the time of a write to the write buffer from the cache memory, an address of a write destination and the addresses stored in the buffers are compared, and when any of the buffers has an agreeing address, data is overwritten to this buffer, and the buffer is logically moved to a last stage.
    Type: Application
    Filed: January 9, 2014
    Publication date: September 18, 2014
    Applicant: FUJITSU LIMITED
    Inventors: Takatoshi FUKUDA, SHUJI TAKADA, Kenjiro Mori
  • Publication number: 20140282435
    Abstract: A performance profiling apparatus includes: a plurality of counters provided for a routine included in a program; a storage section configured to store an instruction of the program and an identification information indicating the routine of the program; a processor configured to read the instruction from the storage section and to execute a process according to the instruction; and a counter controller configured to, at the time of reading the instruction of the processor, receive the identification information of the instruction which is output from the storage section with the instruction and to instruct a first counter designated by the identification information to count up.
    Type: Application
    Filed: November 21, 2013
    Publication date: September 18, 2014
    Applicant: FUJITSU LIMITED
    Inventors: Takatoshi FUKUDA, Shuji TAKADA, Kenjiro MORI
  • Patent number: 8835656
    Abstract: The invention provides a universal linker capable of synthesizing nucleic acid having a hydroxy group at the 3? terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. The linker contains a compound represented by the formula wherein each symbol is as defined in the specification.
    Type: Grant
    Filed: January 30, 2013
    Date of Patent: September 16, 2014
    Assignees: Nitto Denko Corporation, National University Corporation Nagoya University
    Inventors: Masaki Tsukamoto, Noritaka Suzuki, Yoshihiro Hayakawa, Eri Maeta, Kenjiro Mori, Kenjiro Minomi
  • Patent number: 8802745
    Abstract: The present invention relates to a porous resin bead containing a first aromatic monovinyl compound-divinyl compound-(meth)acrylonitrile-second aromatic monovinyl compound copolymer, in which the second aromatic monovinyl compound contains a group capable of binding with a carboxyl group by dehydration condensation reaction, and in which the porous resin bead has a swelling volume in acetonitrile of from 3 to 6 ml/g.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: August 12, 2014
    Assignee: Nitto Denko Corporation
    Inventors: Kenjiro Mori, Eri Maeta, Tatsuya Konishi
  • Patent number: 8669356
    Abstract: The invention provides a universal linker capable of synthesizing nucleic acid having a phosphate group at the 3? terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. The linker for solid phase synthesis of nucleic acid contains a compound represented by at least one of the following formulae wherein each symbol is as defined in the specification.
    Type: Grant
    Filed: October 20, 2010
    Date of Patent: March 11, 2014
    Assignees: Nitto Denko Corporation, National University Corporation Nagoya University
    Inventors: Yoshihiro Hayakawa, Masaki Tsukamoto, Kenjiro Mori, Kenjiro Minomi, Eri Maeta, Tatsuya Konishi
  • Patent number: 8653152
    Abstract: The present invention relates to a porous resin bead containing a first aromatic monovinyl compound-divinyl compound-(meth)acrylonitrile-second aromatic monovinyl compound copolymer, in which the second aromatic monovinyl compound contains a group capable of binding with a carboxyl group by dehydration condensation reaction, and in which the porous resin bead has a dry volume of from 2 to 3 ml/g.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: February 18, 2014
    Assignee: Nitto Denko Corporation
    Inventors: Kenjiro Mori, Tatsuya Konishi, Eri Maeta
  • Publication number: 20130317206
    Abstract: The present invention provides a solid-phase support for oligonucleotide synthesis for synthesizing long chain oligonucleotide, RNA oligonucleotide and modified oligonucleotide at high synthetic quantity and high purity with a low loading amount of a linker. Provided is a solid-phase support for oligonucleotide synthesis comprising a porous resin bead having a monovinyl monomer unit, a crosslinkable vinyl monomer unit and a polyethylene glycol unit and a cleavable linker loaded on its surface, the porous resin bead having a group capable of binding to a carboxy group by a dehydration condensation reaction on its surface, the cleavable linker having a carboxy group, wherein the carboxy group of the cleavable linker is bound to the group capable of binding to a carboxy group, by a dehydration condensation reaction, and a loading amount of the cleavable linker is 1 to 80 ?mol/g relative to the weight of the porous resin bead.
    Type: Application
    Filed: May 23, 2013
    Publication date: November 28, 2013
    Inventors: Eri MAETA, Kenjiro MORI, Kazuya MIWA
  • Patent number: 8592542
    Abstract: The present invention provides porous resin beads containing an aromatic monovinyl compound-divinyl compound-(meth)acrylamide derivative copolymer. Preferably, the copolymer further contains as a structural unit a second aromatic monovinyl compound having a functional group capable of binding to a carboxyl group by a dehydrating condensation reaction.
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: November 26, 2013
    Assignee: Nitto Denko Corporation
    Inventors: Kenjiro Mori, Eri Maeta, Tatsuya Konishi
  • Patent number: 8487013
    Abstract: The present invention relates to a method for producing a porous resin particle containing an aromatic vinyl compound-aromatic divinyl compound copolymer having a hydroxyl group, the method including: dissolving a monomer mixture containing an aromatic vinyl compound, an aromatic divinyl compound and a (meth)acrylic acid ester having one hydroxyl group within the molecule thereof, and a polymerization initiator in an organic solvent to obtain a solution containing the monomer mixture and the polymerization initiator; suspending the solution in water in the presence of a dispersion stabilizer; and performing a suspension copolymerization. The method of the invention is capable of easily producing a porous resin particle containing an aromatic vinyl compound-aromatic divinyl compound copolymer having a hydroxyl group, that is used as a support for solid phase synthesis and enables efficient nucleic acid synthesis.
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: July 16, 2013
    Assignee: Nitto Denko Corporation
    Inventors: Kenjiro Mori, Tatsuya Konishi