Patents by Inventor Kenkichi Masutomi

Kenkichi Masutomi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SCREENING METHOD FOR TELOMERASE REVERSE TRANSCRIPTASE (TERT) PHOSPHORYLATION INHIBITORS
    Publication number: 20230124973
    Abstract: The present invention provides a method for screening for a telomerase reverse transcriptase (TERT) phosphorylation inhibitor using TERT or a fragment thereof, and a TERT kinase.
    Type: Application
    Filed: December 14, 2018
    Publication date: April 20, 2023
    Inventor: Kenkichi MASUTOMI
  • MAMMALIAN RNA DEPENDENT RNA POLYMERASE
    Publication number: 20110243910
    Abstract: The invention provides compositions comprising a TERT-RMRP or TERT-RNA complex and methods of treating subjects with genetic diseases in which gene silencing is either increased by administering the compositions of the invention or decreased by administering an inhibitor of the RNA-dependent RNA polymerase (RdRP) activity of these compositions. Moreover, the invention provides methods of screening for agonists and antagonists of RdRP activity and TERT-RMRP complex formation. Finally, the invention provides a method of identifying a RNA molecule that forms a complex with a TERT polypeptide and has RdRP activity.
    Type: Application
    Filed: July 7, 2009
    Publication date: October 6, 2011
    Applicants: JAPAN HEALTH SCIENCES FOUNDATION, RIKEN, DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: William Hahn, Kenkichi Masutomi, Yoshiko Maida, Yoshihide Hayashizaki, Timo Lassmann
  • Telomerase RNA Subunit and Methods of Use Thereof
    Publication number: 20090047672
    Abstract: The present invention provides a novel telomere associated RNA (hTERC-2) that mediates the DNA repair function of telomerase.
    Type: Application
    Filed: February 7, 2006
    Publication date: February 19, 2009
    Inventors: William C. Hahn, Richard Possemato, Kenkichi Masutomi
  • Method for producing telomerase reverse transcriptase
    Publication number: 20020028496
    Abstract: A method for producing telomerase reverse transcriptase comprising the steps of infecting an insect cell with a baculovirus containing a DNA encoding telomerase reverse transcriptase, and then culturing the infected cell to express the telomerase reverse transcriptase is disclosed.
    Type: Application
    Filed: October 2, 2001
    Publication date: March 7, 2002
    Inventors: Seishi Murakami, Shuichi Kaneko, Kenkichi Masutomi