Abstract: The present disclosure presents a trajectory array guide system for defining a trajectory to a target location in the brain of a subject and for guiding an elongated tool along the trajectory. The trajectory array guide system can comprise: a base, an array guide, an imaging unit, and an elongated handle configured for connection with a stereotaxic navigation system. The present disclosure presents a method of using a trajectory array guide system for defining a trajectory to a target location in the brain of a subject and for guiding an elongated tool along the trajectory.

Abstract: The present disclosure presents a trajectory array guide system for defining a trajectory to a target location in the brain of a subject and for guiding an elongated tool along the trajectory. The trajectory array guide system can comprise: a base, an array guide, an imaging unit, and an elongated handle configured for connection with a stereotaxic navigation system. The present disclosure presents a method of using a trajectory array guide system for defining a trajectory to a target location in the brain of a subject and for guiding an elongated tool along the trajectory.

Abstract: An automatic pool cleaner is provided of the type for random travel over submerged floor and side wall surfaces of a swimming pool or the like to dislodge and collect debris. The pool cleaner includes an electric-powered traction drive system for rotatably driving cleaner wheels, and an electric-powered water management system including a water supply pump and related manifold unit for venturi-vacuuming and collection of settled debris within a porous filter bag. A directional control system including an on-board compass monitors turning movements of the pool cleaner during normal random travel operation, and functions to regulate the traction drive system in a manner to prevent, e.g., excess twisting of a conduit such as a power cable tethered to the pool cleaner.

Abstract: Filters principally for automatic swimming pool cleaners are detailed. The filters include bags of porous material formed into at least two lobes. At least one divider separates a primary flow path through the bags from multiple debris-collecting pockets.

Abstract: An automatic pool cleaner is provided of the type for random travel over submerged floor and side wall surfaces of a swimming pool or the like to dislodge and collect debris. The pool cleaner includes an electric-powered traction drive system for rotatably driving cleaner wheels, and an electric-powered water management system including a water supply pump and related manifold unit for venturi-vacuuming and collection of settled debris within a porous filter bag. A directional control system including an on-board compass monitors turning movements of the pool cleaner during normal random travel operation, and functions to regulate the traction drive system in a manner to prevent, e.g., excess twisting of a conduit such as a power cable tethered to the pool cleaner.

Abstract: Cloning and characterization of a full length cDNA encoding Sp110 (speckled 110), a novel 110 kDa polypeptide, is disclosed. It is disclosed that Sp110 is a component of the nuclear body, is expressed in leukocytes, and is also expressed in other types of cells, including endothelial cells, smooth muscle cells, liver cells and heart cells, after contact with certain cytokines. The disclosure also includes the following: Sp140 recruits Sp110 to the nuclear body, Sp110 functions as an activator of gene transcription, and Sp110 serves as a nuclear hormone receptor co-activator. Sp110 DNAs, polypeptides, antibodies are disclosed. Also disclosed are Sp110-related screening methods and clinical diagnostic methods.

Abstract: Methods for enhancing the therapeutic or prophylactic effectiveness of an inhaled therapeutic gas are disclosed. The methods include administering to a mammal by inhalation a therapeutically effective amount of gaseous nitric oxide or carbon monoxide, and administering to the mammal a composition containing a compound that sensitizes soluble guanylate cyclase.

Abstract: This invention provides an apparatus and method for desalting a low volume solution for use in connection with an electronically addressable microarray. The apparatus comprises a tubular molecular weight cut-off membrane embedded within a ion exchange resin filled chamber. The apparatus provides a very high surface to volume ratio of membrane pore surface to exchange resin capacity for absorbing charged molecules. The design facilitates the speedy removal of charged molecules from test solutions with the resultant desalted solution having a very low ionic strength suitable for use in the electronic transport of nucleic acids, proteins, and cells.

Abstract: There is provided an elastomeric switching device for use with electrical circuits, such as those on a printed circuit board. The elastomeric switching device comprises an elastomeric pad constructed from a plurality of parallel strips of conductive material between layers of non-conductive or insulating material together with a moveable conductive contact which is aligned with the elastomeric pad. The elastomeric pad is predisposed in contact with the circuits on the printed circuit board. The moveable conductive contact establishes electrical connections between the affected circuits via the conductive strips of the elastomeric pad. The proper alignment and orientation of the elastomeric pad and moveable conductive contact relative to the circuits is maintained by the structural and mechanical features of a housing.

Abstract: A video recording system enables self-service production of vended videocassette recordings to a user or customer, with user control of several features. Preferably the system includes forming a composite video picture with the user's image in combination with a user-selected background sequence. Compositing may be by chromakeying, with a key color as a backdrop behind the user in a recording booth. As the composite video recording is made the user preferably is able to watch the composite image on a monitor, which may also include prompting messages for the user. A preferred control for the system involves control data encoded on a videodisc, which also holds a plurality of selectable background sequences.

Abstract: A lock/ejector assembly device for attachment to a printed wiring board. Attachment of an upper and lower such assembly device to a printed wiring board provides locking pressure for stably fixing the printed wiring board into a rack which holds the mother board and its multiple interconnection contacts. A finger-movable snap lock in the assembly provides a "locking" function to fixate the board, or an "unlocking" function to permit removal of the board.