Abstract: Drug screening assays useful in the discovery of pharmaceutically active compounds for use in the treatment of diseases involving abnormal lipid metabolism including diabetic neuropathy are taught. In particular, the control region of delta-5-desaturase gene is taught as a target for the drug screening methods, which serve to identify nucleotides, proteins, compounds and/or other pharmacological agents, which modulate the activity of desaturase enzymes or regulate the level of expression of the desaturase genes. Cell-based and cell lysate assays are taught for detecting components that interact with the desaturase enzymes and modify fatty acid profiles. In addition, cell-based and cell lysate assays are used to identify functional and regulatory elements controlling expression of the desaturase genes as well as to screen for components that modulate the transcriptional activity of the desaturase genes. Also taught is the gene for rat delta-5-desaturase.

Abstract: The present invention relates to elongase genes, their polypeptides and their control regions, and the use of such genes, polypeptides and control regions in determining compositions for use in the treatment of disease. The identified compositions regulate the expression of the elongase genes or modulate the activity of their protein products. The nucleotide and amino acid sequences are taught for ELG4, ELG6 and ELG7. The control sequences and function are taught for ELG1, ELG2, ELG3, ELG4, ELG5, ELG6 and ELG7.

Abstract: A system and method of data flow management, particularly in a multiple network processor architecture where a plurality of independent processing units are simultaneously processing information from different frames of input information. The present invention includes first-in-first-out files identifying the individual frames and correlating the frames with the processor to which the frames have been assigned for processing as well as a first-in-first-out file of processed frames for each processor to allow the frames to be processed independently, then reassembled into the same order as the frames had been received without communication between the independent processors.

Abstract: In an ordered semaphore management system a pending state allows threads not competing for a locked semaphore to bypass one or more threads waiting for the same locked semaphore. The number of pending levels determines the number of consecutive threads vying for the same locked semaphore which can be bypassed. When more than one level is provided the pending levels are prioritized in the queued order.

Abstract: Processor threads in a multi-processor system can concurrently lock multiple semaphores by providing a lock command which includes the semaphore value and a semaphore number. Each processor is allocated two or more addressable semaphore stores, each of which include a multi-bit field identifying the requested semaphore and a one bit field identifying the locked status of the requested semaphore. The semaphore number determines which of the allocated semaphore stores are to be used for processing the lock command.

Abstract: A generic method and apparatus for managing semaphores in a multi-threaded processing system has a storage area for each of the threads in the processing system. Each storage area includes a first part for storing at least one indicia for identifying at least one unique semaphore from a plurality of semaphores utilized by the multi-threaded processing system and a second part for storing an indicia for indicating a locked status for the stored semaphore. A thread requiring a semaphore sends a semaphore lock request to the semaphore manager which examines the contents of all of the storage areas to determine the status of the requested semaphore. If the requested semaphore is not locked, it is locked for the requesting thread by inserting the requested semaphore and locked status in the memory location assigned to the requesting thread.

Abstract: An ordered semaphore management subsystem and method for use in an application system which includes a plurality of processors competing for shared resources each of which is controlled by a unique semaphore. The subsystem generates an ordered semaphore field (OSF) corresponding to each processor in a linked list of processors and assigns one of four statuses to the OSF depending on the position the processor occupies in the linked list of processors competing for the shared resources. The four states are (1) semaphore head (SH); (2) behind semaphore head (BSH); (3) semaphore head behind (SHB); and (4) skip (Skip). Only the SH processor is allocated the semaphore when requested. A processor not in the SH state will be denied the semaphore even if is available to assure sequential access.

Abstract: The ability of network processors to move data to and from dynamic random access memory (DRAM) chips used in computer systems is enhanced in several respects. In one aspect of the invention, two double data rate DRAMS are used in parallel to double the bandwidth for increased throughput of data. The movement of data is further improved by setting 4 banks of full ‘read’ and 4 banks of full ‘write’ by the network processor for every repetition of the DRAM time clock. A scheme for randomized ‘read’ and ‘write’ access by the network processor is disclosed. This scheme is particularly applicable to networks such as Ethernet that utilize variable frame sizes.

Abstract: A motor vehicle dryer stand including a base member having a pair of laterally spaced legs projecting remotely from the base member, a standard projecting upward from the proximal end portion of the base member, an elongated lamp arm and means for clamping one end of the lamp arm at selected vertically adjusted positions on the standard, the lamp arm being of a length sufficient to extend over the top of a motor vehicle for supporting a dryer lamp over the center portion of the motor vehicle when the standard is in a position proximate to the side of the motor vehicle. Both the standard and the lamp arm are adapted to support one or more dryer lamps, and the standard may be fitted with additional lamp arms for supporting additional dryer lamps. The lamp arms extend preferably in the same longitudinal vertical plane of the base member.

Abstract: Furnace apparatus and method, for the continuous electric heating or fusion of particulate mineral-bearing substances, wherein a cylindrical furnace housing is adapted to trunnion bearing, the housing having at least one detachable and elongated conical extension at ends for dumping, the extensions likewise having electrode openings which are coaxially aligned with the housing, whereby a charge of the mineral-bearing substance may be introduced either during fusion or heating or roasting or firing, thus permitting partial filling of the furnace housing and sequential build-up, protecting the respective ends of the furnace against dead space and excessive charge recycle. By virtue of design, the conical ends are shielded against burning out by unbearable heat generated from the electrode arc. Inherent advantages occur by highly accelerated rotation, yielding resultant centrifugal forces which are applied to the charge.