Patents by Inventor Kenneth A. Kramer

Kenneth A. Kramer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Wet granulation formulation for bisphosphonic acids
    Publication number: 20040137056
    Abstract: Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by wet granulation tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease. These compositions are prepared without the addition of binder; instead, the drug itself acts as a binder.
    Type: Application
    Filed: December 19, 2003
    Publication date: July 15, 2004
    Inventors: Ashok V. Katdare, Kenneth A. Kramer
  • Effervescent bisphosphonate formulation
    Publication number: 20040137058
    Abstract: An effervescent formulation of alendronate contains an acid source, a carbonate source, a binder, a lubricant and optionally, flavoring agents, colorants and sweeteners.
    Type: Application
    Filed: January 5, 2004
    Publication date: July 15, 2004
    Inventors: Ashok V. Katdare, Kenneth A. Kramer, Colin R. Gardner
  • Wet granulation formulation for bisphosphonic acids
    Patent number: 6692764
    Abstract: Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by wet granulation tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease. These compositions are prepared without the addition of binder; instead, the drug itself acts as a binder.
    Type: Grant
    Filed: September 23, 2002
    Date of Patent: February 17, 2004
    Assignee: Merck & Co., Inc.
    Inventors: Ashok V. Katdare, Kenneth A. Kramer
  • Wet granulation formulation for bisphosphonic acids
    Publication number: 20030032628
    Abstract: Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by wet granulation tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease. These compositions are prepared without the addition of binder; instead, the drug itself acts as a binder.
    Type: Application
    Filed: September 23, 2002
    Publication date: February 13, 2003
    Applicant: Merck & Co., Inc.
    Inventors: Ashok V. Katdare, Kenneth A. Kramer
  • Dry mix formulation for bisphosphonic acids
    Patent number: 6517867
    Abstract: Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by direct compression/dry mix tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease.
    Type: Grant
    Filed: October 19, 2001
    Date of Patent: February 11, 2003
    Assignee: Merck & Co., Inc.
    Inventors: Simon R. Bechard, Kenneth A. Kramer, Ashok V. Katdare
  • Effer-vescent bisphosphonate formulation
    Publication number: 20030003147
    Abstract: An effervescent formulation of alendronate contains an acid source, a carbonate source, a binder, a lubricant and optionally, flavoring agents, colorants and sweeteners.
    Type: Application
    Filed: July 9, 2002
    Publication date: January 2, 2003
    Applicant: Merck & Co., Inc.
    Inventors: Ashok V. Katdare, Colin R. Gardner, Kenneth A. Kramer
  • Wet granulation formulation for bisphosphonic acids
    Publication number: 20020137727
    Abstract: Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by wet granulation tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease. These compositions are prepared without the addition of binder; instead, the drug itself acts as a binder.
    Type: Application
    Filed: March 4, 2002
    Publication date: September 26, 2002
    Applicant: Merck & Co., Inc.
    Inventors: Ashok V. Katdare, Kenneth A. Kramer
  • Dry mix formulation for bisphosphonic acids
    Patent number: 6406714
    Abstract: Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by direct compression/dry mix tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease.
    Type: Grant
    Filed: October 17, 2000
    Date of Patent: June 18, 2002
    Assignee: Merck & Co., Inc.
    Inventors: Simon R. Bechard, Kenneth A. Kramer, Ashok V. Katdare
  • Dry mix formulation for bisphosphonic acids
    Publication number: 20020054906
    Abstract: Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by direct compression/dry mix tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease.
    Type: Application
    Filed: October 19, 2001
    Publication date: May 9, 2002
    Applicant: MERCK & Co., Inc.
    Inventors: Simon R. Bechard, Kenneth A. Kramer, Ashok V. Katdare
  • Effervescent bisphosphonate formulation
    Publication number: 20010041165
    Abstract: An effervescent formulation of alendronate contains an acid source, a carbonate source, a binder, a lubricant and optionally, flavoring agents, colorants and sweeteners.
    Type: Application
    Filed: June 11, 2001
    Publication date: November 15, 2001
    Applicant: MERCK & CO., Inc.
    Inventors: Ashok V. Katdare, Colin R. Gardner, Kenneth A. Kramer
  • Wet granulation formulation for bisphosphonic acids
    Publication number: 20010007863
    Abstract: Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by wet granulation tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease. These compositions are prepared without the addition of binder; instead, the drug itself acts as a binder.
    Type: Application
    Filed: February 15, 2001
    Publication date: July 12, 2001
    Applicant: MERCK & CO., Inc.
    Inventors: Ashok V. Katdare, Kenneth A. Kramer
  • Dry mix formulation for bisphosphonic acids
    Patent number: 6194004
    Abstract: Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by direct compression/dry mix tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease.
    Type: Grant
    Filed: November 2, 1999
    Date of Patent: February 27, 2001
    Assignee: Merck & Co., Inc.
    Inventors: Simon R. Bechard, Kenneth A. Kramer, Ashok V. Katdare
  • Dry mix formulation for bisphosphonic acids
    Patent number: 6090410
    Abstract: Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by direct compression/dry mix tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease.
    Type: Grant
    Filed: August 28, 1998
    Date of Patent: July 18, 2000
    Assignee: Merck & Co., Inc.
    Inventors: Simon R. Bechard, Kenneth A. Kramer, Ashok V. Katdare
  • Dry mix formulation for bisphosphonic acids
    Patent number: 5882656
    Abstract: Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by direct compression/dry mix tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease.
    Type: Grant
    Filed: October 8, 1997
    Date of Patent: March 16, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Simon R. Bechard, Kenneth A. Kramer, Ashok V. Katdare
  • Effervescent alendronate formulation
    Patent number: 5853759
    Abstract: An effervescent formulation of alendronate contains an acid source, a carbonate source, a binder, a lubricant and optionally, flavoring agents, colorants and sweeteners.
    Type: Grant
    Filed: May 8, 1997
    Date of Patent: December 29, 1998
    Assignee: Merck & Co.. Inc.
    Inventors: Ashok V. Katdare, Kenneth A. Kramer, Colin R. Gardner
  • Dry mix formulation for bisphosphonic acids
    Patent number: 5681590
    Abstract: Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by direct compression/dry mix tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease.
    Type: Grant
    Filed: July 26, 1995
    Date of Patent: October 28, 1997
    Assignee: Merck & Co., Inc.
    Inventors: Simon R. Bechard, Kenneth A. Kramer, Ashok V. Katdare
  • Tablet
    Patent number: D375157
    Type: Grant
    Filed: December 22, 1992
    Date of Patent: October 29, 1996
    Assignee: Merck & Co., Inc.
    Inventors: Kenneth A. Kramer, Ashok V. Katdare
  • Pharmaceutical tablet
    Patent number: D379223
    Type: Grant
    Filed: September 13, 1995
    Date of Patent: May 13, 1997
    Assignee: Merck & Co., Inc.
    Inventors: Kenneth A. Kramer, Ashok V. Katdare
  • Pharmaceutical tablet
    Patent number: D380825
    Type: Grant
    Filed: October 31, 1994
    Date of Patent: July 8, 1997
    Assignee: Merck & Co., Inc.
    Inventors: Kenneth A. Kramer, Ashok Katdare
  • Pharmaceutical tablet
    Patent number: D400672
    Type: Grant
    Filed: March 21, 1996
    Date of Patent: November 3, 1998
    Assignee: Merck & Co., Inc.
    Inventors: Kenneth A. Kramer, Ashok V. Katdare