Abstract: A cartridge holding unit includes a cartridge container forming an outer surface of the cartridge holding unit and having an inner space, and a cartridge holder forming a tube-shaped holding section arranged in the inner space of the cartridge container, the cartridge holder configured to firmly hold a cartridge in parallel with the cartridge holder and the cartridge holder and the cartridge container are firmly coupled to each other regarding their axial orientations.

Abstract: A dose delivery mechanism includes a housing, a piston rod that acts on a plunger sealing a fluid compartment and moves in an axial direction relative to the housing to deliver a set dose, and a dose setting member that is movable relative to the housing during dose setting. A position of the dose setting member relative to the housing defines the set dose, and in an as-delivered condition the dose setting member is preset to a position that corresponds to a set dose higher than zero.

Abstract: A set includes a medicament delivery device with a dose delivery activation mechanism that is configured to adjust the medicament delivery device from an inactive state to an active state in which a dose is deliverable, and a cover. The cover is mechanically attached to the medicament delivery device prior to use of the medicament delivery device, and is configured to cover at least a part of the dose delivery activation mechanism so that a user is restrained from prematurely activating the medicament delivery device. The cover is configured to be movable in a distal direction to uncover the part of the dose delivery activation mechanism to activate the medicament delivery device during use of the medicament delivery device.

Abstract: A dose setting mechanism configured to set a desired dose for an injection device, the dose setting mechanism includes a housing, a dose setting knob, a dose setting device and a coupling element. The dose setting knob is configured to set the desired dose by a compulsory guided combined axial and rotational movement of the dose setting knob relative to the housing. Upon drug delivery, the dose setting knob is moved axially relative to the dose setting device or the housing and the coupling element is configured to engage at least one of the dose setting device and the housing to thereby permanently axially lock the dose setting knob to the respective one of the dose setting device and the housing.

Abstract: A dose delivery mechanism includes a piston rod and a nut. The piston rod forms an outer thread meshing with an inner thread of the nut, and during dose setting, the nut is rotated relative to the piston rod to advance the nut with respect to the piston rod by a first distance into a distal direction, an actuation member that is movable by a user to effect delivery of a set dose, and a housing. A second threaded connection is configured to cause the actuation member to travel a second distance into the distal direction during dose setting. The actuation member is coupled via the nut to the piston rod during dose delivery to advance the piston rod by the first distance into a proximal direction upon proximal movement of the actuation member by the second distance, and the second distance is less than 1.5 times the first distance.

Abstract: A dose delivery mechanism for a medicament delivery device includes a housing, a piston rod, and an adjusting element. The housing is configured to connect to a medicament container sealed by a plunger. In the assembled state, the dose delivery mechanism is configured to move the piston rod axially in a proximal direction with respect to the housing during dose delivery such that the piston rod exerts an axial force in the proximal direction on the plunger of the medicament container to expel a medicament from the medicament container.

Abstract: The present invention relates to a automated spraying device for spraying an enclosure with a liquid cleanser, the device having,—a reservoir (16) for containing the liquid cleanser,—a pump (14) in fluid communication with the reservoir, and—a movable spray head (15) having an outlet orifice through which cleanser from the reservoir can be expelled during operation of the pump if there is such liquid cleanser in the reservoir. Said spraying device also contains an electrical motor drive mechanism (12) for sequentially operating th pump (14) and moving the spray head (15) to modify the direction of the spray there from, such that the spray head is not simultaneously spraying and moving. Furthermore, the spray head is suitable for producing an aerosol whereby the Dv50 of the aerosol is in the range of from 30 to 70 micron.

Abstract: This document relates to delivery devices for dispensing fluid materials, including high viscosity fluids such as high viscosity surgical adhesives. For example, methods and materials for an integrated system of containing and permitting point of use delivery of a high viscosity adhesive fluid onto a planar surface of tissue during a surgical procedure are provided.

Abstract: The present invention relates to a automated spraying device for spraying an enclosure with a liquid cleanser, the device having, a reservoir (16) for containing the liquid cleanser, a pump (14) in fluid communication with the reservoir, and a movable spray head (15) having an outlet orifice through which cleanser from the reservoir can be expelled during operation of the pump if there is such liquid cleanser in the reservoir. Said spraying device also contains an electrical motor drive mechanism (12) for sequentially operating th pump (14) and moving the spray head (15) to modify the direction of the spray there from, such that the spray head is not simultaneously spraying and moving. Furthermore, the spray head is suitable for producing an aerosol whereby the Dv50 of the aerosol is in the range of from 30 to 70 micron.

Abstract: A ribbed seal for use in endoscopic surgery is intended to be incorporated into a cannula assembly to limit the escape of insufflation gasses from a body cavity by forming a fluid-tight seal around an instrument inserted through the cannula assembly. The ribbed seal includes a relatively flat, disk shaped elastomeric overmold portion having a central aperture sized slightly smaller than the instrument such that the aperture must expand to accommodate the instrument. Molded together with the elastomeric overmold is an array of slender ribs disposed about the aperture. The ribs are designed to be relatively flexible under lateral loads. This allows the seal to bend easily as the surgical instrument is inserted through the aperture thereby maintaining a low insertion and glide force. On the other hand, the ribs are designed to be relatively rigid when loaded axially. This rigidity provides robust radial support for the instrument inserted through the center of the array of ribs.

Abstract: A surgical portal apparatus includes a portal housing, an elongated portal member connected to the portal housing and an armature assembly. The portal housing and the portal member have an axial bore for reception and passage of a surgical object. The armature assembly includes at least two arms disposed within the portal housing and an outer mount. The at least two arms extend at least radially inwardly and are adapted to move relative to the longitudinal axis from a rest position to an activated position during passage of the surgical object. The at least two arms are operatively connected whereby movement of a first arm causes corresponding movement of a second arm. The outer mount comprises a resilient material and is mounted to the at least two arms, and imparts a biasing force thereto toward the rest position.

Abstract: A surgical portal apparatus includes a portal housing, an elongated portal member connected to the portal housing and an armature assembly. The portal housing and the portal member have an axial bore for reception and passage of a surgical object. The armature assembly includes at least two arms disposed within the portal housing and an outer mount. The at least two arms extend at least radially inwardly and are adapted to move relative to the longitudinal axis from a rest position to an activated position during passage of the surgical object. The at least two arms are operatively connected whereby movement of a first arm causes corresponding movement of a second arm. The outer mount comprises a resilient material and is mounted to the at least two arms, and imparts a biasing force thereto toward the rest position.

Abstract: A surgical access apparatus includes a housing, an access member extending from the housing and having a longitudinal passageway for passage of an object and defining trailing and leading ends and an elongated seal mechanism mounted relative to the housing. The elongated seal mechanism includes a trailing hub and a leading hub longitudinally spaced from the trailing hub, and being adapted for relative rotational movement about the longitudinal axis, a plurality of spokes extending between and connected to the trailing hub and the leading hub, and an elongated seal member disposed within the spokes and adapted to establish a sealing relation about the object. The spokes define a first minimum internal dimension in a first condition thereof in the absence of an object and defining a second minimum internal dimension in a second condition thereof upon insertion of the object and relative rotation of the trailing hub and the leading hub.

Abstract: A surgical access apparatus includes a housing member, a portal member extending from the housing member and defining a central longitudinal axis, and defining a longitudinal passage therethrough dimensioned to permit passage of an surgical object and a constraining mechanism associated with at least one of the housing member and the portal member. The constraining mechanism includes a constraining member dimensioned and positioned to intersect the longitudinal passage. The constraining member is adapted to engage the surgical object and bias the surgical object toward a position radially displaced relative to the central longitudinal axis. The constraining member is adapted to transition from an initial condition in the absence of the surgical object to a stressed condition in the presence of the surgical object. The constraining member may be normally biased toward the initial condition.

Abstract: A ribbed seal for use in endoscopic surgery is intended to be incorporated into a cannula assembly to limit the escape of insufflation gasses from a body cavity by forming a fluid-tight seal around an instrument inserted through the cannula assembly. The ribbed seal includes a relatively flat, disk shaped elastomeric overmold portion having a central aperture sized slightly smaller than the instrument such that the aperture must expand to accommodate the instrument. Molded together with the elastomeric overmold is an array of slender ribs disposed about the aperture. The ribs are designed to be relatively flexible under lateral loads. This allows the seal to bend easily as the surgical instrument is inserted through the aperture thereby maintaining a low insertion and glide force. On the other hand, the ribs are designed to be relatively rigid when loaded axially. This rigidity provides robust radial support for the instrument inserted through the center of the array of ribs.

Abstract: A ribbed seal for use in endoscopic surgery is intended to be incorporated into a cannula assembly to limit the escape of insufflation gasses from a body cavity by forming a fluid-tight seal around an instrument inserted through the cannula assembly. The ribbed seal includes a relatively flat, disk shaped elastomeric overmold portion having a central aperture sized slightly smaller than the instrument such that the aperture must expand to accommodate the instrument. Molded together with the elastomeric overmold is an array of slender ribs disposed about the aperture. The ribs are designed to be relatively flexible under lateral loads. This allows the seal to bend easily as the surgical instrument is inserted through the aperture thereby maintaining a low insertion and glide force. On the other hand, the ribs are designed to be relatively rigid when loaded axially. This rigidity provides robust radial support for the instrument inserted through the center of the array of ribs.

Abstract: This document relates to delivery devices for dispensing fluid materials, including high viscosity fluids such as high viscosity surgical adhesives. For example, methods and materials for an integrated system of containing and permitting point of use delivery of a high viscosity adhesive fluid onto a planar surface of tissue during a surgical procedure are provided.

Abstract: A surgical access apparatus includes a housing member and a portal member extending from the housing member and defining a longitudinal axis. The housing member and the portal member define a longitudinal passage therethrough dimensioned to permit passage of an elongated object. A centering mechanism is mounted relative to the housing member. The centering mechanism includes an annular element mounted for rotational movement within the housing member and about the longitudinal axis and first and second arm elements mounted to the annular element and extending radially inwardly relative to the longitudinal axis. The first and second arm elements are each positioned to intersect the longitudinal passage and are adapted to pivot relative to the housing member.

Abstract: A surgical access apparatus includes a housing member and a portal member extending from the housing member and defining a longitudinal axis. The housing member and the portal member define a longitudinal passage therethrough dimensioned to permit passage of an elongated object. A centering mechanism is mounted relative to the housing member. The centering mechanism includes an annular element mounted for rotational movement within the housing member and about the longitudinal axis and first and second arm elements mounted to the annular element and extending radially inwardly relative to the longitudinal axis. The first and second arm elements are each positioned to intersect the longitudinal passage and are adapted to pivot relative to the housing member.

Abstract: A surgical access apparatus includes a housing, an access member extending from the housing and having a longitudinal passageway for passage of an object and defining trailing and leading ends and an elongated seal mechanism mounted relative to the housing. The elongated seal mechanism includes a trailing hub and a leading hub longitudinally spaced from the trailing hub, and being adapted for relative rotational movement about the longitudinal axis, a plurality of spokes extending between and connected to the trailing hub and the leading hub, and an elongated seal member disposed within the spokes and adapted to establish a sealing relation about the object. The spokes define a first minimum internal dimension in a first condition thereof in the absence of an object and defining a second minimum internal dimension in a second condition thereof upon insertion of the object and relative rotation of the trailing hub and the leading hub.