Patents by Inventor Kenneth Barrett

Kenneth Barrett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11634698
    Abstract: Disclosed herein are polypeptides having nuclease activity. Some of the polypeptides having nuclease activity were generated by an improved gene site mutagenesis (“GSSM”) method or the tailored multi-site combinatorial assembly (“TMCA”) method. Also disclosed are compositions and kits comprising the polypeptides having nuclease activity, and methods for making and using these polypeptides, compositions and kits.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: April 25, 2023
    Assignee: BASF SE
    Inventors: Xuqiu Tan, Kenneth Barrett, Jared Dennis, Dongmei Ren, Corey Dodge, Bin Zhang
  • Patent number: 11286621
    Abstract: Embodiments disclosed herein provide enzymatic formulations comprising a polypeptide having amylase activity for producing a paper product. Also provided are aqueous surface treatment compositions for paper and board comprising degraded starch. Further provided are methods for producing paper and board using the aqueous surface treatment composition, and to corrugated boards produced from this paper.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: March 29, 2022
    Assignee: BASF SE
    Inventors: Christoph Hamers, Konstantino Karanikas, Kenneth Barrett, Zheng Tan
  • Patent number: 11198881
    Abstract: The present disclosure concerns recombinant yeast host cell for saccharification of a biomass. The recombinant yeast host cell has a genetic modification for expressing a heterologous polypeptide having glucoamylase activity (Rasamsonia emersonii glucoamylase). In some embodiments, the heterologous polypeptide comprises the signal sequence associated with the alpha-mating 1 factor. The present disclosure also concerns a process for saccharification of a biomass using the recombinant yeast host cell as well as a process for fermenting the saccharified biomass into a fermentation product.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: December 14, 2021
    Assignees: Lallemand Hungary Liquidity Management LLC, BASF SE
    Inventors: Aaron Argyros, Alexandra Panaitiu, Charles Rice, Kenneth Barrett
  • Publication number: 20210163967
    Abstract: The present disclosure concerns recombinant yeast host cell for saccharification of a biomass. The recombinant yeast host cell has a genetic modification for expressing a heterologous polypeptide having glucoamylase activity (Rasamsonia emersonii glucoamylase). In some embodiments, the heterologous polypeptide comprises the signal sequence associated with the alpha-mating 1 factor. The present disclosure also concerns a process for saccharification of a biomass using the recombinant yeast host cell as well as a process for fermenting the saccharified biomass into a fermentation product.
    Type: Application
    Filed: November 25, 2020
    Publication date: June 3, 2021
    Inventors: Aaron Argyros, Alexandra Panaitiu, Charles Rice, Kenneth Barrett
  • Publication number: 20210163995
    Abstract: The present disclosure concerns a process for fermenting a biomass with a reduced dose of a purified exogenous enzyme (which can be, for example a purified exogenous glucoamylase). The process comprises contacting a biomass (which may comprise starch) with a recombinant yeast host cell. The recombinant yeast host cell has a genetic modification for expressing a heterologous polypeptide having starch or dextrin hydrolase activity (which may be, for example, from a glucoamylase). The nucleic acid molecule encoding the heterologous polypeptide having starch or dextrin hydrolase activity comprises allowing the secretion of the heterologous polypeptide.
    Type: Application
    Filed: November 25, 2020
    Publication date: June 3, 2021
    Inventors: Aaron Argyros, Alexandra Panaitiu, Charles Rice, Matthew B. Richards, Tera Stoughtenger, Kenneth Barrett
  • Publication number: 20210139871
    Abstract: Disclosed herein are polypeptides having nuclease activity. Some of the polypeptides having nuclease activity were generated by an improved gene site mutagenesis (“GSSM”) method or the tailored multi-site combinatorial assembly (“TMCA”) method. Also disclosed are compositions and kits comprising the polypeptides having nuclease activity, and methods for making and using these polypeptides, compositions and kits.
    Type: Application
    Filed: December 10, 2018
    Publication date: May 13, 2021
    Inventors: Xuqiu TAN, Kenneth BARRETT, Jared DENNIS, Dongmei REN, Corey DODGE, Bin ZHANG
  • Publication number: 20190376052
    Abstract: The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta-D-glucan 4-glucano hydrolase activity) and comprises hydrolysis of 1,4-beta-D-glycosidic linkages in cellulose, cellulose derivatives (e.g., carboxy methyl cellulose and hydroxy ethyl cellulose) lichenin, beta-1,4 bonds in mixed beta-1,3 glucans, such as cereal beta-D-glucans or xyloglucans and other plant material containing cellulosic parts. In addition, methods of designing new enzymes and methods of use thereof are also provided. In alternative aspects, the new glucanases e.g., endoglucanases, mannanases, xylanases have increased activity and stability, including thermotolerance or thermostability, at increased or decreased pHs and temperatures.
    Type: Application
    Filed: May 28, 2019
    Publication date: December 12, 2019
    Inventors: Brian Steer, Shaun Healey, Alireza Esteghlalian, Stacy Marie Miles, Kenneth Barrett, Rene Quadt
  • Publication number: 20190271115
    Abstract: Embodiments disclosed herein provide enzymatic formulations comprising a polypeptide having amylase activity for producing a paper product. Also provided are aqueous surface treatment compositions for paper and board comprising degraded starch. Further provided are methods for producing paper and board using the aqueous surface treatment composition, and to corrugated boards produced from this paper.
    Type: Application
    Filed: August 12, 2016
    Publication date: September 5, 2019
    Applicant: BASF SE
    Inventors: Christoph HAMERS, Konstantino KARANIKAS, Kenneth BARRETT, Zheng TAN
  • Patent number: 10329549
    Abstract: The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta-D-glucan 4-glucano hydrolase activity) and comprises hydrolysis of 1,4-beta-D-glycosidic linkages in cellulose, cellulose derivatives (e.g., carboxy methyl cellulose and hydroxy ethyl cellulose) lichenin, beta-1,4 bonds in mixed beta-1,3 glucans, such as cereal beta-D-glucans or xyloglucans and other plant material containing cellulosic parts. In addition, methods of designing new enzymes and methods of use thereof are also provided. In alternative aspects, the new glucanases e.g., endoglucanases, mannanases, xylanases have increased activity and stability, including thermotolerance or thermostability, at increased or decreased pHs and temperatures.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: June 25, 2019
    Assignee: BP Corporation North America Inc.
    Inventors: Brian Steer, Shaun Healey, Alireza Esteghlalian, Stacy Marie Miles, Kenneth Barrett, Rene Quadt
  • Publication number: 20140295523
    Abstract: The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta-D-glucan 4-glucano hydrolase activity) and comprises hydrolysis of 1,4-beta-D-glycosidic linkages in cellulose, cellulose derivatives (e.g., carboxy methyl cellulose and hydroxy ethyl cellulose) lichenin, beta-1,4 bonds in mixed beta-1,3 glucans, such as cereal beta-D-glucans or xyloglucans and other plant material containing cellulosic parts. In addition, methods of designing new enzymes and methods of use thereof are also provided. In alternative aspects, the new glucanases e.g., endoglucanases, mannanases, xylanases have increased activity and stability, including thermotolerance or thermostability, at increased or decreased pHs and temperatures.
    Type: Application
    Filed: March 28, 2014
    Publication date: October 2, 2014
    Applicant: BP Corporation North America Inc.
    Inventors: Brian Steer, Shaun Healey, Alireza Esteghlalian, Stacy Marie Miles, Kenneth Barrett, Rene Quadt
  • Publication number: 20110117067
    Abstract: The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta-D-glucan 4-glucano hydrolase activity) and comprises hydrolysis of 1,4-beta-D-glycosidic linkages in cellulose, cellulose derivatives (e.g., carboxy methyl cellulose and hydroxy ethyl cellulose) lichenin, beta-1,4 bonds in mixed beta-1,3 glucans, such as cereal beta-D-glucans or xyloglucans and other plant material containing cellulosic parts. In addition, methods of designing new enzymes and methods of use thereof are also provided. In alternative aspects, the new glucanases e.g., endoglucanases, mannanases, xylanases have increased activity and stability, including thermotolerance or thermostability, at increased or decreased pHs and temperatures.
    Type: Application
    Filed: August 4, 2007
    Publication date: May 19, 2011
    Inventors: Alireza Esteghlalian, Kenneth Barrett, Shaun Healey, Stacy M. Miles, Rene Quadt