Patents by Inventor Kenneth Borow

Kenneth Borow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF TREATING PROGRESSIVE HEART FAILURE IN SUBJECTS AT HIGH RISK OF POOR OUTCOMES
    Publication number: 20250090589
    Abstract: The present disclosure relates to methods for treating and/or preventing progressive heart failure in subjects at high risk of poor outcomes. Such methods may be used for treating or preventing progressive heart failure in subjects with micro-vascular disease and/or macro-vascular disease.
    Type: Application
    Filed: November 17, 2022
    Publication date: March 20, 2025
    Inventors: Silviu ITESCU, Kenneth BOROW
  • METHOD OF TREATING PROGRESSIVE HEART FAILURE IN SUBJECTS WITH CLASS II HEART FAILURE
    Publication number: 20240041934
    Abstract: The present disclosure relates to methods for treating and/or preventing progressive heart failure in subjects with earlier stages of heart failure. Such method may be used for treating or preventing progressive heart failure in subjects with Class II heart failure according to the New York Heart Association (NYHA) classification scale.
    Type: Application
    Filed: December 15, 2021
    Publication date: February 8, 2024
    Inventors: Silviu ITESCU, Kenneth BOROW, Jack HAYES
  • METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE
    Publication number: 20220280593
    Abstract: The invention provides methods of treating an obstructive coronary artery disease in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof and performing a coronary artery bypass graft procedure on the subject.
    Type: Application
    Filed: October 29, 2021
    Publication date: September 8, 2022
    Applicant: Stealth BioTherapeutics Inc.
    Inventors: Kenneth Borow, D. Travis Wilson
  • METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE
    Publication number: 20210046146
    Abstract: The invention provides methods of treating an obstructive coronary artery disease in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof and performing a coronary artery bypass graft procedure on the subject.
    Type: Application
    Filed: March 24, 2020
    Publication date: February 18, 2021
    Applicant: Stealth BioTherapeutics Corp
    Inventors: Kenneth Borow, D. Travis Wilson
  • METHODS FOR THE PREVENTION OR TREATMENT OF VESSEL OCCLUSION INJURY
    Publication number: 20210023160
    Abstract: This invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to a subject in need thereof, wherein the peptide is D-Arg-2 6-Dmt-Lys-Phe-NH2 (SS-31).
    Type: Application
    Filed: February 28, 2020
    Publication date: January 28, 2021
    Applicant: Stealth Biotherapeutics Corp
    Inventors: Kenneth Borow, D. Travis Wilson
  • METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE
    Publication number: 20190365845
    Abstract: The invention provides methods of treating an obstructive coronary artery disease in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof and performing a coronary artery bypass graft procedure on the subject.
    Type: Application
    Filed: October 23, 2018
    Publication date: December 5, 2019
    Inventors: Kenneth Borow, D. Travis Wilson
  • METHODS FOR THE PREVENTION OR TREATMENT OF VESSEL OCCLUSION INJURY
    Publication number: 20190336566
    Abstract: This invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to a subject in need thereof, wherein the peptide is D-Arg-2 6-Dmt-Lys-Phe-NH2 (SS-31).
    Type: Application
    Filed: December 5, 2018
    Publication date: November 7, 2019
    Inventors: Kenneth Borow, D. Travis Wilson
  • Methods for the prevention or treatment of no-reflow following ischemia/reperfusion injury
    Patent number: 10322159
    Abstract: The invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods provide administering aromatic-cationic peptides in effective amounts to prevent or treat an anatomic zone of no re-flow in mammalian subjects. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof.
    Type: Grant
    Filed: May 18, 2016
    Date of Patent: June 18, 2019
    Assignees: STEALTH BIOTHERAPEUTICS CORP, GOOD SAMARITAN INSTITUTE FOR RESEARCH AND EDUCATION
    Inventors: D. Travis Wilson, Kenneth Borow, Robert A. Kloner, Sharon Hale
  • METHODS FOR THE PREVENTION OR TREATMENT OF VESSEL OCCLUSION INJURY
    Publication number: 20180228864
    Abstract: This invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to a subject in need thereof, wherein the peptide is D-Arg-2 6-Dmt-Lys-Phe-NH2 (SS-31).
    Type: Application
    Filed: September 27, 2017
    Publication date: August 16, 2018
    Inventors: Kenneth Borow, D. Travis Wilson
  • METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE
    Publication number: 20180117112
    Abstract: The invention provides methods of treating an obstructive coronary artery disease in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof and performing a coronary artery bypass graft procedure on the subject.
    Type: Application
    Filed: June 14, 2017
    Publication date: May 3, 2018
    Inventors: Kenneth Borow, D. Travis Wilson
  • METHODS FOR THE PREVENTION OR TREATMENT OF VESSEL OCCLUSION INJURY
    Publication number: 20170100451
    Abstract: This invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to a subject in need thereof, wherein the peptide is D-Arg-2 6-Dmt-Lys-Phe-NH2 (SS-31).
    Type: Application
    Filed: May 26, 2016
    Publication date: April 13, 2017
    Inventors: Kenneth Borow, D. Travis Wilson
  • METHODS FOR THE PREVENTION OR TREATMENT OF NO-REFLOW FOLLOWING ISCHEMIA/REPERFUSION INJURY
    Publication number: 20170087204
    Abstract: The invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods provide administering aromatic-cationic peptides in effective amounts to prevent or treat an anatomic zone of no re-flow in mammalian subjects. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof.
    Type: Application
    Filed: May 18, 2016
    Publication date: March 30, 2017
    Inventors: D. Travis WILSON, Kenneth BOROW, Robert A. KLONER, Sharon HALE
  • METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE
    Publication number: 20170028015
    Abstract: The invention provides methods of treating an obstructive coronary artery disease in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof and performing a coronary artery bypass graft procedure on the subject.
    Type: Application
    Filed: February 11, 2016
    Publication date: February 2, 2017
    Applicant: Stealth BioTherapeutics Corp.
    Inventors: Kenneth Borow, D. Travis Wilson
  • METHODS FOR THE PREVENTION OR TREATMENT OF VESSEL OCCLUSION INJURY
    Publication number: 20160151444
    Abstract: The invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof.
    Type: Application
    Filed: July 6, 2015
    Publication date: June 2, 2016
    Inventors: Kenneth Borow, D. Travis Wilson
  • Methods for the prevention or treatment of no-reflow following ischemia/reperfusion injury
    Patent number: 9345738
    Abstract: The invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods provide administering aromatic-cationic peptides in effective amounts to prevent or treat an anatomic zone of no re-flow in mammalian subjects. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: May 24, 2016
    Assignees: Stealth BioTherapeutics Corp., Heart Institute Good Samaritan Hospital
    Inventors: D. Travis Wilson, Kenneth Borow, Robert A. Kloner, Sharon Hale
  • METHODS FOR THE PREVENTION OR TREATMENT OF VESSEL OCCLUSION INJURY
    Publication number: 20160030501
    Abstract: This invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to a subject in need thereof, wherein the peptide is D-Arg-2 6-Dmt-Lys-Phe-NH2 (SS-31).
    Type: Application
    Filed: March 6, 2015
    Publication date: February 4, 2016
    Inventors: Kenneth Borow, D. Travis Wilson
  • METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE
    Publication number: 20150320824
    Abstract: The invention provides methods of treating an obstructive coronary artery disease in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof, and performing a coronary artery bypass graft procedure on the subject.
    Type: Application
    Filed: April 4, 2014
    Publication date: November 12, 2015
    Applicant: Stealth Peptides International, Inc.
    Inventors: Kenneth Borow, D. Travis Wilson
  • METHODS FOR THE PREVENTION OR TREATMENT OF VESSEL OCCLUSION INJURY
    Publication number: 20140341879
    Abstract: This invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to a subject in need thereof wherein the peptide is D-Arg-26-Dmt-Lys-Phe-NH2 (SS-31).
    Type: Application
    Filed: January 7, 2014
    Publication date: November 20, 2014
    Applicant: Stealth Peptides International, Inc.
    Inventors: Kenneth Borow, D. Travis Wilson
  • METHODS FOR THE PREVENTION OR TREATMENT OF NO-REFLOW FOLLOWING ISCHEMIA/REPERFUSION INJURY
    Publication number: 20130196921
    Abstract: The invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods provide administering aromatic-cationic peptides in effective amounts to prevent or treat an anatomic zone of no re-flow in mammalian subjects. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof.
    Type: Application
    Filed: July 8, 2011
    Publication date: August 1, 2013
    Inventors: D. Travis Wilson, Kenneth Borow, Robert A. Kloner, Sharon Hale
  • METHODS FOR THE PREVENTION OR TREATMENT OF VESSEL OCCLUSION INJURY
    Publication number: 20130195837
    Abstract: This invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to a subject in need thereof, wherein the peptide is D-Arg-2 6-Dmt-Lys-Phe-NH2 (SS-31).
    Type: Application
    Filed: December 30, 2010
    Publication date: August 1, 2013
    Inventors: Kenneth Borow, D. Travis Wilson